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Pacemaker (ICD) Clinical Trials

A listing of Pacemaker (ICD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (14) clinical trials

Medtronic, Inc. is sponsoring the World-wide Randomized Antibiotic EnveloPe Infection PrevenTion Trial (WRAP-IT), a randomized, prospective, multi-center, single blinded, post market, interventional clinical study. The study has three purposes. First, the WRAP-IT study will serve as a post-approval study for those geographies requiring a post-approval study to facilitate collection of ...

Phase N/A

Studies have shown that patients who have large areas of cardiac muscle damage also have a clear correlation in the ST shifts in their ECGs. St. Jude Medical has developed a device that will perform continuous monitoring of the ST segment. This device is attached to the right ventricular tip ...

Phase N/A

Identification of NICM patients who are likely to develop ventricular tachyarrhythmias is challenging.   In the light of MADIT-RIT and ADVANCE III trials, modern programming of ICDs is targeting faster (188-200 bpm) and longer (>30 beats) episodes of ventricular tachyarrhythmias, that might serve as the endpoint related to a reduction ...

Phase N/A

Prospective Database for Prediction of Atrial Fibrillation in Pacemaker and ICD Patients

Atrial fibrillation (AF) is associated with a five-fold increased risk of cerebrovascular stroke. While the risk of stroke in patients with known AF can be calculated via AF stroke prediction risk scores, the prediction of AF occurrence per se in individual patients remains difficult. We will recruit 250 patients with ...

Phase N/A

Prognosis of Patients With Compete Left Bundle Branch Block

The effect of cardiac resynchronization therapy (CRT) for heart failure patients was heterogeneous. Candidate selection was important before intervention. The underlying mechanical dyssynchrony of left ventricular bundle branch block was insufficiently descripted. Earlier study of investigators found novel imaging methods such as cardiovascular magnetic resonance imaging including T1 Mapping and ...

Phase N/A

Multi-centre Observational Registry on Patients With Implantable Devices Remotely Monitored

Multicentric, observational, retrospective registry including patients underwent implantable device implantation (pacemaker or ICD) for any indication in the period from 2009 to 2016, followed by remote monitoring. The aims of the registry are to evaluate the occurrence of atrial arrhythmias, of hospitalizations, and the mortality during a long-term follow-up.

Phase N/A

Safety of Magnetic Resonance Imaging in Non-MRI Conditional Pacemakers and ICD Devices

The primary objective of the study is to determine the safety of MRI in patients with non-MRI conditional pacemakers. The secondary objective is to determine if there are clinically relevant parameter changes in the devices.

Phase N/A

Dasatinib and Bevacizumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot be Removed by Surgery

OBJECTIVES: Primary - To describe the safety and toxicity of the combination of dasatinib and bevacizumab in patients with advanced solid tumors that have progressed on standard therapy. - To find the maximum tolerated dose or recommended phase II dose of this combination. - To describe the biochemical changes in ...


11C-Acetate PET/CT Non-FDG-Avid Tumors

Recent publications have suggested the use of 11C-acetate as another PET tracer for tumor imaging. The accumulation of 11C-acetate in tumor cells is related to the highly active lipid metabolism in the cell membrane associated with tumor growth. 11C-acetate is channeled into the tricarboxylic acid cycle via acetyl coenzyme A ...

Phase N/A

Long Term Effects of Tyrosine Kinase Inhibitor Therapy on Ovarian Reserve and Fertility in Patients With Chronic Myeloid Leukemia or Gastrointestinal Stromal Tumor

PRIMARY OBJECTIVES: I. To collect preliminary information to help design a study to look at longitudinal changes in markers of ovarian reserve and menstruation in premenopausal women undergoing tyrosine kinase inhibitors (TKI) therapy. SECONDARY OBJECTIVES: I. Evaluate ovarian response to controlled ovarian hyperstimulation in patients who elect to undergo in ...

Phase N/A