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Chordoma Clinical Trials

A listing of Chordoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (8) clinical trials

Randomized Carbon Ions vs Standard Radiotherapy for Radioresistant Tumors

This is a transnational prospective randomized trial comparing definitive carbon ion therapy versus photon or combined photon and protontherapy as standard treatment for unresectable or macroscopically uncompleted resected radioresistant tumors. Eligible tumors are axial chordoma (except of base of skull), adenoid cystic carcinoma of head and neck (except of trachea) ...

Phase N/A

A Study of IMRT in Primary Bone and Soft Tissue Sarcoma

IMRiS is a prospective multicentre phase II trial of Intensity Modulated Radiotherapy (IMRT). The trial is aiming to evaluate the role of intensity modulated radiotherapy (IMRT) in soft tissue and bone sarcomas. Three separate sarcoma cohorts will be studied and will be analysed separately. Patients will be enrolled in one ...

Phase N/A

Study of Individuals and Families at High Risk for Cancer

OBJECTIVES: - Identify individuals at high risk of cancer, especially due to personal or family medical history. - Evaluate and define clinical spectrum of disease in syndromes predisposing to cancer. - Quantify risks of tumors in family members. - Map, clone, and determine function of tumor susceptibility genes. - Identify ...

Phase N/A

Natural History Study of Patients With Central Nervous System Tumors Being Evaluated at the National Institutes of Health

OBJECTIVES: - Evaluate patients with CNS tumors who are probable future candidates for NCI phase I and II protocols. - Follow patients with CNS tumors that are representative of important scientific and/or clinical principles. - Attain a steady flow of patients with CNS tumors at the NIH, which will help ...

Phase N/A

Identifying New Families With Multiple Members Affected by Chordoma

OBJECTIVES: - To determine the feasibility of conducting a larger study encompassing the remaining English-speaking patients at Massachusetts General Hospital with chordoma. - To identify new families with multiple members affected by chordoma to participate in clinical and gene mapping studies. OUTLINE: Patients complete a questionnaire about demographics (education, marital ...

Phase N/A

Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes

Background Chordoma is a rare, slow growing, often fatal bone cancer derived from notochord remnants. It occurs in the axial skeleton (skull base, vertebrae, sacrum, coccyx), is more frequent in males, and has a median age at diagnosis of 58.5 years, with a wide age range. This typically sporadic tumor ...

Phase N/A

Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease

International, multicenter, comparative, open-label, parallel-group, mixed Observational-Randomized Controlled Trial. All the patients, who are candidate for the study will receive full information on the characteristics, potential effectiveness and side effects of the two alternatives treatments: radiotherapy (RT) and surgical treatment Eligible patients will be asked to be randomized in order ...

Phase N/A

Children and Adults With Chordoma

Background Chordomas are a rare tumor with an incidence of 325 new cases per year in the United States. Pediatric chordomas are very rare and comprise only 5% of all chordoma cases. The standard therapy for localized primary or recurrent chordomas is surgical resection. However, complete surgical resection is often ...

Phase N/A