Lymphoproliferative disorders Clinical Trials

A listing of Lymphoproliferative disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 176 clinical trials
Allogeneic Hematopoietic Stem Cell Transplant for People With Primary Immunodeficiency Diseases

Background During a transplant, blood stem cells from one person are given to someone else. The cells grow into the different cells that make up the immune system. This can cure people with certain immunodeficiencies. But transplant has many risks and complications. Objective To see if stem cell transplant can …

alemtuzumab
vaccination
therapeutic agents
immunodeficiency
stem cell transplantation
  • 0 views
  • 12 Sep, 2021
  • 1 location
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Background Allogeneic blood or marrow transplant is when stem cells are taken from one person s blood or bone marrow and given to another person. Researchers think this may help people with immune system problems. Objective To see if allogeneic blood or bone marrow transplant is safe and effective in …

urine test
therapeutic agents
bone marrow transplant
immunodeficiency
lymphoma
  • 439 views
  • 12 Sep, 2021
  • 2 locations
Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

Background Blood stem cells in the bone marrow make all the cells to normally defend a body against disease. Allogeneic blood or marrow transplant is when these stem cells are transferred from one person to another. Researchers think this treatment can provide a new, healthy immune system to correct T-cell …

urine test
therapeutic agents
bone marrow transplant
cell transplantation
neutropenia
  • 138 views
  • 12 Sep, 2021
  • 2 locations
Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma

The purpose of this study is to find out whether acupuncture treatments can reduce the need for opioid medication when managing pain caused by chemotherapy. The study will compare the effects of adding acupuncture to usual pain management with those of usual pain management alone, in reducing opioid use by …

pain management
high dose chemotherapy
lymphoma
multiple myeloma
cancer
  • 0 views
  • 23 Sep, 2021
  • 2 locations
Safety and Immunogenicity of an Epstein-Barr Virus (EBV) gp350-Ferritin Nanoparticle Vaccine in Healthy Adults With or Without EBV Infection

Background Epstein-Barr virus (EBV) causes most cases of infectious mononucleosis (mono). Up to 1 in 10 people who get mono can have fatigue that lasts more than 6 months. One out of 100 people can have severe complications. EBV is also associated with several types of cancer. Researchers want to …

cancer
  • 0 views
  • 23 Sep, 2021
  • 1 location
TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas

Background TRC102 is a new cancer treatment drug that may help improve the results of chemotherapy. It blocks tumor cells' attempts to repair damaged DNA, which may allow chemotherapy to kill the cells more easily. Researchers want to see how well it works with temozolomide, a chemotherapy drug that is …

bisphosphonate
chemotherapy regimen
liver metastasis
solid tumour
nitrosoureas
  • 11 views
  • 12 Sep, 2021
  • 1 location
ALPN-202 With PD-1 Inhibition in Advanced Malignancies

This is a cohort-based, open-label dose escalation and expansion study in adults with advanced solid tumors or lymphoma.

lymphoma
solid tumor
cancer
measurable disease
  • 0 views
  • 12 Sep, 2021
  • 4 locations
Venetoclax Ibrutinib Prednisone Obinutuzumab and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Background B-cell lymphoma is a cancer of white blood cells found in the lymph nodes. It affects the system that fights infections and disease. Researchers want to learn how certain drugs work together to treat B-cell lymphomas. The drugs are venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide (ViPOR). Objective To study …

g-csf
lenalidomide
mantle cell lymphoma
gilbert's syndrome
transformed lymphoma
  • 69 views
  • 12 Sep, 2021
  • 1 location
Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors

Background Researchers want to develop better ways to treat cancer. In this study, they will give people with cancer two drugs. These drugs have been used on their own to treat some blood cell cancers. Objectives To test the safety and efficacy of the drug combination of bortezomib and clofarabine. …

bortezomib
bisphosphonate
cancer
neuropathy
primary cancer
  • 25 views
  • 12 Sep, 2021
  • 1 location
Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

This study will gain information about a rare disorder called KSHV-associated multicentric Castleman s disease (MCD). KSHV, a virus, causes several kinds of cancer, including some forms of MCD. KSHV stands for the Kaposi s sarcoma herpes virus, also called human herpes virus-8, or HHV-8. Researchers want to understand the …

ganciclovir
bortezomib
cyclophosphamide
valganciclovir
filgrastim
  • 57 views
  • 22 Sep, 2021
  • 1 location