Lymphoproliferative disorders Clinical Trials

A listing of Lymphoproliferative disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 17 clinical trials
LCCC1841: A Phase 2 Trial of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas

The purpose of this study is to see if acalabrutinib is effective in treating a type of cancer call central nervous system (CNS) lymphoma. Acalabrutinib has not been approved by the Food and Drug Administration (FDA) for the treatment of CNS lymphoma. However, FDA has approved its use for treatment …

ibrutinib
mantle cell lymphoma
cancer
lymphoma
anticancer agents
  • 0 views
  • 23 Jul, 2021
  • 3 locations
Double Filtration Plasmapheresis Combined With Chemotherapy

Evaluation of double filtration plasmapheresis combined with chemotherapy for the treatment of abnormalities of M protein or renal function due to the multiple myeloma.

chemotherapy regimen
bone marrow procedure
  • 0 views
  • 24 Jul, 2021
  • 1 location
A Study of Pembrolizumab Added to the Standard First-Line Therapy of Cyclophosphamide Bortezomib and Dexamethasone (CyBorD) for NDMM NTE

This is a phase 2A multi-centre, open label, pilot study of pembrolizumab added to the standard first-line therapy of cyclophosphamide, bortezomib and dexamethasone (CyBorD) in newly diagnosed patients with multiple myeloma that are not eligible for autologous stem cell transplantation.

bortezomib
dexamethasone
  • 0 views
  • 31 Jul, 2021
  • 4 locations
Phase II Study of Daratumumab Pre-Mobilization and Post-ASCT in Multiple Myeloma

This study will use the drug daratumumab in patients who did not achieve at least a very good partial response (VGPR) and are already planned to have an Autologous Stem Cell Transplant (ASCT). Daratumumab will be given before the stem cell collection to attempt to get rid of any multiple …

measurable disease
platelet count
white blood cells
human chorionic gonadotropin
bone marrow procedure
  • 0 views
  • 01 Aug, 2021
  • 1 location
Steroid Sparing Treatment With in Newly Diagnosed Transplant Ineligible Patients With Multiple Myeloma

The purpose of this study is to determine the effects of daratumumab and lenalidomide without steroids for treating patients with multiple myeloma.

chemotherapy regimen
dexamethasone
lenalidomide
  • 0 views
  • 01 Aug, 2021
  • 1 location
Physical Activity for Myeloma Autograft Longitudinal Study

Physical exercises program is known to improve quality of life, chronical fatigue and appears to be a behavioural recommendation against cancer as primary and tertiary prevention. Nutritional status is also important in cancer patients: a loss of 5% of weight increases the complication risks and decreases survival and the quality …

chemotherapy regimen
melphalan
cell transplantation
cancer
  • 0 views
  • 31 Jul, 2021
  • 1 location
Isatuximab Lenalidomide Bortezomib and Dexamethasone in NDMM

This research is testing whether the investigational drug isatuximab is safe and effective when used in combination with standard agents for the treatment of newly diagnosed multiple myeloma.

measurable disease
dexamethasone
platelet count
bortezomib
lenalidomide
  • 0 views
  • 01 Aug, 2021
  • 1 location
Venetoclax Ibrutinib Prednisone Obinutuzumab and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

Background Aggressive B-cell lymphomas can be cured but people with disease that resists treatment or that returns after treatment have poor outcomes with standard therapies. Indolent B-cell lymphomas are generally incurable with standard therapy and treatment is aimed at controlling symptoms and achieving a durable remissions. Researchers want to see …

venetoclax
filgrastim
cancer
flow cytometry
ibrutinib
  • 0 views
  • 24 Jul, 2021
  • 1 location
Study to Evaluate t(11;14) Status and BCL2 Expression in Adult Participants With Multiple Myeloma (MM)

Multiple myeloma (MM) is a rare cancer caused by abnormal survival of plasma cells (blood cells). Most trial participants with MM relapse (cancer has come back) or become nonresponsive to treatment and remission gets shorter after each line of treatment. This is a study to assess t(11;14) and BCL2 expression …

bone marrow procedure
cancer
  • 0 views
  • 30 Jul, 2021
  • 40 locations
DOLPHIN-VIVO: Diagnosis Of LymPHoma IN Vivo (Ex Vivo Phase)

Lymphoma diagnosis often involves removal and biopsy of one or more lymph nodes. Many (around half) of these diagnostic procedures show that no cancer is present, hence unnecessary removal results in numerous side effects and complications. The procedure is also highly invasive. The investigators have already shown that it is …

  • 0 views
  • 01 Aug, 2021
  • 1 location