Birth Defects Clinical Trials

A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 184 clinical trials
Live Birth After Additional Tubal Flushing With Oil-based Contrast Versus no Additional Flushing:

congenital anomaly, neonatal outcomes and thyroid function, pregnancy complications, number of complications during or immediately after the intervention, pain score of the Hyfosy and additional flush

  • 0 views
  • 19 Jul, 2021
  • 12 locations
Gastroschisis Outcomes of Delivery (GOOD) Study

The objective of this study is to investigate the hypothesis that delivery at 35 0/7- 35 6/7 weeks in stable patients with gastroschisis is superior to observation and expectant management with a goal of delivery at 38 0/7 - 38 6/7 weeks. To test this hypothesis, we will complete a …

  • 228 views
  • 22 Jul, 2021
  • 20 locations
Post-Authorization Safety Study (PASS) of LysaKare in Adult Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) Patients

The purpose of the study is to evaluate the effect of arginine/lysine solution administration on serum potassium levels. A systematic assessment of serum potassium levels will be performed during infusion and up to 24 hours post start of infusion compared to baseline.

  • 0 views
  • 01 Aug, 2021
  • 10 locations
South-seq: Deoxyribonucleic Acid (DNA) Sequencing for Newborn Nurseries in the South

2,000 infants with signs suggestive of a genetic disorder being treated at a neonatal intensive care unit (NICU) in which African-American and rural populations are highly represented will be enrolled. Whole genome sequencing (WGS) will be used to identify pathogenic variation in DNA from these infants. Stakeholders, including parents, clinicians, …

  • 0 views
  • 25 Jul, 2021
  • 3 locations
Correction of Fixed Knee Flexion Deformity in Children Using Eight-plate Hemiepiphysiodesis

The study aims to assess the effectiveness of hemiephysiodesis using eight plates in correction of fixed knee flexion deformities in children.

  • 0 views
  • 28 Jul, 2021
  • 1 location
Daytime Bright Light Circadian Abnormalities and Delirium in Medical ICU Patients

To determine if daytime bright light will promote circadian alignment and shorten or prevent delirium.

  • 0 views
  • 24 Jul, 2021
  • 1 location
Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

The ApiFix MID-C System is a unidirectional expandable rod, designed to be connected unilaterally to the spine via 2 anchor points on the concave side of a scoliotic deformity above and below

x-rays
  • 5 views
  • 31 Jul, 2021
  • 21 locations
rAAV-Olig001-ASPA Gene Therapy for Treatment of Children With Typical Canavan Disease

result in loss of ASPA catabolic activity result in a typically severe phenotype characterized by chronically elevated brain NAA, gross motor abnormalities, hypomyelination, progressive spongiform

  • 0 views
  • 02 Aug, 2021
  • 1 location
Target Therapy With GEMOX in Recectable Gallbladder Carcinoma Patients Monitored by ctDNA

The purpose of this study is to evaluate the feasibility, efficacy and safety of target therapy according to genomic and proteomic profiling combined with GEMOX in recectable gallbladder carcinoma patients monitored by ctDNA.

  • 0 views
  • 01 Aug, 2021
  • 1 location
Phenylalanine and Its Impact on Cognition

The PICO-Study is a randomized, placebo-controlled, crossover, non-inferiority trial conducted to add evidence to the current European treatment guidelines for adult patients with phenylketonuria.

phenylalanine
neonatal screening
  • 8 views
  • 20 Jul, 2021
  • 1 location