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Birth Defects Clinical Trials

A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (27) clinical trials

Pregnancy Environment and Newborn Malformations

Population based case-control study: 2 controls per case will be included, corresponding to the first 2 births without congenital anomalies, with same sex and same birth place, following the case. INVESTIGATION METHODOLOGY : All maternity in Brittany were proposed to participate. In each maternity, the referent practitioner informs the parents ...

Phase N/A

Renal Agenesis Fetal Therapy

In fetal life, urine production by the kidneys is responsible for sustaining amniotic fluid in the uterus. This fluid is critical for fetal lung development during gestation. Complete lack of amniotic fluid, known as anhydramnios, leads to lethal pulmonary hypoplasia in 100% of patients. A common cause of complete anhydramnios ...

Phase N/A

Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission

This is a multicenter, prospective, randomized, open-label and parallel two arm study starting from week 14-16 of pregnancy to post-partum week 28. The enrollment from approximately 7 centers will be in blocks for sample balance. By using the randomized table, 280 HBeAg-positive pregnant women with chronic hepatitis B (CHB) will ...

Phase

Personalized Genomic Research

Recent advances in genomic techniques are making possible a new wave of genetic discovery. We hope to couple genomic techniques with more traditional methods involved in genetic discovery in order to investigate a broad range of conditions for which there is strong evidence that genetic factors are involved. To accomplish ...

Phase N/A

A clinical research study for the treatment of Hepatitis C virus, CONGENITAL ANOMALY NOS, Pregnancy Complications, Atresia, Hepatitis C

Ribavirin, a nucleoside analog with antiviral activity, is used in combination with interferons or pegylated interferons for the treatment of chronic hepatitis C (HCV). Extensive clinical studies have demonstrated that combination therapy with ribavirin and interferons or pegylated interferons are efficacious treatments for HCV. However, ribavirin has been assigned a ...

Phase N/A

Flucelvax (TIVc or QIVc) Pregnancy Registry

The study is a population based prospective cohort study designed to collect data on pregnancy outcomes and events of interest among women immunized with the TIVc or QIVc vaccine during pregnancy.

Phase N/A

Afluria Pregnancy Registry

The study is a population based prospective cohort study designed to collect data on pregnancy outcomes and events of interest among women immunized with Afluria during pregnancy.

Phase N/A

Genomic Sequencing and Personalized Treatment for Birth Defects in Neonatal Intensive Care Units

Neonatal congenital malformation is one of the most frequent cause of infant death in the western world and major cities of China. There are many different types of congenital malformations, and some of these can be caused by changes in gene mutation. Next generation sequencing (NGS) is a high-throughput parallel ...

Phase N/A

'TOTAL' (Tracheal Occlusion To Accelerate Lung Growth) Trial

This is a multi-center, non-blinded randomized controlled trial in fetuses with isolated moderate CDH, i.e. moderate lung hypoplasia (as determined by prenatal assessment of lung development). It essentially compares fetal therapy added to conventional postnatal care, versus expectant prenatal management during pregnancy followed by conventional postnatal care. Enrollment Following completion ...

Phase

BioThrax (Anthrax) Vaccine in Pregnancy Registry

This study will use a convenience sample and passive referral to enroll participants. For the maternal outcome portion of the study, pregnant active duty women who consent to join the registry are expected to complete several surveys over the course of their pregnancy, including an initial enrollment survey, a follow-up ...

Phase N/A