High Blood Pressure (Hypertension) Clinical Trials

A listing of High Blood Pressure (Hypertension) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 220 clinical trials
Detection of Subclinical Cerebral Suffering Related to Hypertension Using Multimodal MRI

Investigators propose here to study the brain consequences of hypertension in patients without cognitive complaints and neurological signs. The evaluation of brain suffering requires considering various possible brain damage. The team developed a multimodal MRI approach capable of detecting and quantifying numerous indices (e.g. morphometric, microstructural) to evaluate possible brain …

  • 0 views
  • 11 Feb, 2021
  • 1 location
Blood Pressure-Improving Control Among Alaska Native People" (BP-ICAN) (CHAR2)

The investigators have designed a group randomized, multi-level, sustainable stroke and cardiovascular disease (CVD) prevention trial - "Blood Pressure: Improving Control among Alaska Native People" (BP-ICAN) - that targets blood pressure control among Alaska Native and American Indian people diagnosed with hypertension. Washington State University will assist with design, provides …

diabetes
stroke
cardiovascular disease
hbpm
atrial fibrillation
  • 0 views
  • 24 May, 2022
  • 2 locations
mGlide RCT: A Clinical Glide Path To Close the Guideline-to-Practice Gap In HTN Management

Hypertension (HTN) is the most important stroke and cardiovascular disease (CVD) risk factor. Unfortunately, there is substantial under-treatment of HTN. Of the 86 million adults with prevalent

hypertension
systolic blood pressure
cardiovascular disease
stroke
  • 5 views
  • 03 Feb, 2022
  • 1 location
Nesiritide in Hypertension

Hypertension remains a global burden in cardiovascular disease leading to stroke, myocardial infarction, and heart failure. Its myocardial complications result from increased mechanical load on the heart. Under physiological conditions of increased myocardial load and resulting myocardial stretch, atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) synthesis and secretion …

renin
systolic blood pressure
myocardial infarction
stroke
cardiovascular disease
  • 6 views
  • 22 Jan, 2021
  • 3 locations
Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Chlorthalidone (CTD) may produce various metabolic disturbances, including hypokalemia, activation of Renin-Angiotensin- Aldosterone (RAA) system, oxidative stress, dyslipidemia, Fibroblast growth factor 23 (FGF23) synthesis, and magnesium depletion. These factors may interact with each other to contribute to the development of insulin resistances and metabolic syndrome. Smaller studies have suggested that …

insulin
renin
dyslipidemia
thiazide
diuretics
  • 24 views
  • 21 Mar, 2022
  • 3 locations
Study 1: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients

Hypertension (HTN) is the single most prevalent risk factor for cardiovascular disease, diabetes, obesity and metabolic syndrome. Recent American Heart Association (AHA) statistics indicate that

metabolic syndrome
diabetes
cardiovascular disease
diuretics
systolic blood pressure
  • 41 views
  • 08 Jun, 2022
  • 1 location
Neural Mechanism of Aldosterone-induced Insulin Resistance

Patients with high aldosterone hormone have higher blood glucose than normal people. This study is being done to understand how aldosterone hormone affects the nerve activity that controls blood flow in the muscles and blood glucose. The information may be helpful in selecting blood pressure medications which can improve not …

insulin
aldosterone
essential hypertension
hypertension
insulin resistance
  • 70 views
  • 06 Apr, 2022
  • 1 location
Efficacy and Safety of a Single-pill Fixed Combination of Sufficient Losartan/Hydrochlorothiazide in Chinese Hypertensive Patients

Study name: Efficacy and safety of a single-pill fixed combination of sufficient losartan/hydrochlorothiazide in Chinese hypertensive patients (FOCUS) Medicine: Losartan 100 mg/hydrochlorothiazide 25 mg single-pill fixed combination; amlodipine besylate tablet (5 mg/tablet); hydrochlorothiazide tablets (25 mg/tablet) Rationale: Angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) combined with thiazide diuretic …

hydrochlorothiazide
angiotensin converting enzyme
thiazide
systolic blood pressure
diuretics
  • 0 views
  • 06 Feb, 2022
  • 1 location
Effect of a Probiotic on Blood Pressure in Low-to-moderate Risk Grade 1 Hypertension - a Randomized Study (HYPRO)

High blood pressure is a major risk factor for cardiovascular events, including stroke, heart and kidney failure. Typical anti-hypertensive drugs target vessels, the kidneys or the heart. Here we propose a randomized, placebo-controlled study to test the blood pressure-lowering effect of a probiotic in 110 patients with grade 1 hypertension. …

renal failure
hypertension
stroke
antihypertensive drugs
  • 3 views
  • 18 Oct, 2022
  • 1 location
Nicotinamide Riboside as an Enhancer of Exercise Therapy in Hypertensive Older Adults (The NEET Trial)

More than 80% of older adults have hypertension, with higher prevalence of high systolic blood pressure (SBP) putting them at high risk for cardiovascular (CV) disease and death. Novel compound, nicotinamide riboside may enhance the effects of exercise therapy in hypertensive older adults.

systolic blood pressure
hypertension
hypertensive medication
  • 0 views
  • 14 Oct, 2022
  • 1 location