High Blood Pressure (Hypertension) Clinical Trials

A listing of High Blood Pressure (Hypertension) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 20 clinical trials
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

antihypertensive therapy
angiography
antihypertensive drugs
renal angiogram
hypertensive medication
  • 877 views
  • 28 Jul, 2021
  • 83 locations
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

beta-blocker
beta blockers
diuretics
calcium channel blockers
ralinepag
  • 5462 views
  • 26 Jul, 2021
  • 297 locations
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

cardiopulmonary exercise testing
stress test
exercise stress test
ralinepag
endothelin receptor antagonist
  • 0 views
  • 29 Jul, 2021
  • 31 locations
Mindfulness and Neural Cardiovascular Control in Humans

This study evaluates the impact of mindfulness-based stress reduction (MBSR) on sympathetic nerve activity and arterial stiffness. The investigator's central hypothesis is that MBSR will reduce sympathetic activity and arterial stiffness.

blood pressure diastolic
systolic blood pressure
  • 2 views
  • 31 Jul, 2021
  • 1 location
A Study to Evaluate ALN-AGT01 in Patients With Hypertension

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) effects of subcutaneous (SC) ALN-AGT01 in participants with hypertension. The study will be conducted in 4 parts: Part A will be a single ascending dose (SAD) phase in hypertensive participants, Part B will be …

hypertensive medication
electrocardiogram
body mass index
hypertension
irbesartan
  • 370 views
  • 23 Jul, 2021
  • 4 locations
A Pharmacist Intervention for Monitoring and Treating Hypertension Using Bidirectional Texting

Bidirectional texting is an effective way to collect home blood pressure (BP) measurements from subjects, but collecting BP measurements and sending them to physicians does not necessarily lead to decreased BP. Pharmacist interventions have been successful in decreasing subject BP. However, pharmacists are expensive, and in successful interventions, spent a …

hypertension
  • 49 views
  • 18 Jul, 2021
  • 1 location
A Study to Assess the Safety Tolerability and Efficacy of IONIS-AGT-LRx in Hypertensive Participants With Uncontrolled Blood Pressure

The purpose of this study is to evaluate the effect of IONIS-AGT-LRx compared to placebo on systolic blood pressure (SBP) from baseline to Study Day 85 in uncontrolled hypertensive participants on 3 antihypertensive medications and to evaluate the effect of IONIS-AGT-LRx on SBP, diastolic blood pressure (DBP) and plasma angiotensinogen …

angiotensin
beta blockers
body mass index
blood pressure diastolic
potassium
  • 0 views
  • 31 Jul, 2021
  • 35 locations
Resveratrol and Cardiovascular Health in the Elderly

Background Resveratrol is a compound found in the skin of red grapes. It is being tested to see if it can have positive effects on human health. Lab studies show that it may help lower blood sugar, improve heart and blood vessel health, and prevent cancer. Researchers want to test …

stress test
cancer
  • 291 views
  • 31 Jul, 2021
  • 1 location
Hypertension Intervention to Reduce Osteonecrosis in Children With Acute Lymphoblastic Leukemia/Lymphoma

This is a randomized unblinded Phase II clinical trial evaluating the impact of intensive antihypertensive control (targeted to the 50-75th percentile for age, sex, and height) compared to conventional antihypertensive control (targeted to the 90-95th percentile for age, sex, and height) on the incidence of radiographically extensive osteonecrosis in children …

lymphoblastic leukemia
antihypertensive therapy
antihypertensive drugs
lisinopril
hypertension
  • 0 views
  • 28 Jul, 2021
  • 1 location
Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans

Experimental data have shown that timing of sodium intake impacts diurnal patterns of sodium excretion. The purpose of this study is to test the hypothesis that the time of day for salt intake impacts (1) blood pressure rhythms and urinary sodium excretion and (2) circadian timing of factors responsible for …

hypertension
  • 0 views
  • 30 Jul, 2021
  • 1 location