Intrauterine Device Clinical Trials

The Clinical Research Center at EVMS is conducting a clinical trial looking at two intrauterine devices, one approved and one experimental, for contraception. 

The intrauterine device (IUD) is a long-term birth control method that has demonstrated high contraceptive efficacy and effectiveness due to its high compliance, adherence and persistence of use. The IUD has a global prevalence rate around 14% in women of reproductive age. Side effects are the main reason for IUD ...

Stage 1 Study Visits: The Levonorgestrel IUD: This study will have 2 stages. If you are found to be eligible to take part in this study, in Stage 1, you will receive the levonorgestrel IUD. The levonorgestrel IUD is a T-shaped birth control device that is made of flexible plastic. ...

A cross-sectional, observational multicenter study to assess the reasons for choosing the 3-year hormonal IUD and level of IUDs knowledge among women aged 18 to 29 years. The study will be conducted in standard clinical practice conditions at public and private gynecology clinics and during a single study visit. Approximately ...

Women seeking emergency contraception (EC) frequently report multiple recent episodes of unprotected sex. Although high sensitivity urine pregnancy tests effectively rule-out pregnancy resulting from sex that occurred more than 14 days ago, clinicians are frequently concerned that pregnancy may result from unprotected sex that occurred <14 days prior to IUD ...

A randomized clinical controlled trial of women undergoing IUD insertion. Participants in the study groups will be randomly assigned by labeled opaque envelopes to either1% lidocaine (Xylocaine 1%, Astra Zeneca, Egypt), misoprostol (Sigma, Egypt), naproxen (Naprosyn, Syntax, Egypt) or placebo tablets.

Intrauterine balloon and IUD are both effective in the therapy for intrauterine adhesion. The IUD is usually inserted into the uterine after a hysteroscopic adhesiolysis and removed after two or three month later. Several investigators demonstrated its favorable effect in the recurrence of adhesion after the treatment of intrauterine adhesion. ...

New users of the LNG IUS will be eligible. Subjects will be randomized to receive tamoxifen 10 mg BID for 7 days or placebo. Study drug will be started 3 weeks after placement of the IUS. Subjects will maintain a record of daily bleeding and spotting using an electronic text ...

This study will be a prospective randomized controlled trial comparing cold compression to no intervention immediately prior to and during intrauterine device insertion. Inclusion criteria include all non-pregnant women, 18 years of age or older, presenting to the VCU Women's Health clinics with desired IUD placement. Subjects will be identified ...

The optimal interval between pregnancies is debated, but a duration greater than 11-18 months has been suggested as reducing complications in the subsequent pregnancy. Improved birth spacing can be a key benefit use of long-acting reversible contraception, but delay to initiation can still be problematic.So women who have recently given ...