Viral Infections Clinical Trials

The Primary Objective if this study is to evaluate the efficacy of SHP640 based on clinical resolution (Defined as absence of bulbar conjunctival injection and ocular conjunctival discharge) compared with placebo in the treatment of subject with Adenoviral Conjunctivitis in the study at Visit 3(Day5).

Washington University seeks participants for a research study to look at the effects of viral/bacterial infection before or during pregnancy. There is one 30 minute study visit which includes a blood draw, stool collection and nose swab and questionnaire. Study visit will occur after 26 weeks of pregnancy. Possible risks ...

This research is being done to try to test whether a drug called Furosemide Topical Gel (CLS006) is safe and can help people with common warts. The doctor is also doing this study to compare Furosemide Topical Gel with placebo, a gel that looks like Furosemide Topical Gel but doesn’t ...

PRIMARY OBJECTIVES: I. To determine whether substituting adjuvant concurrent high dose cisplatin (CDDP) and fluorouracil (5-FU) with gemcitabine (gemcitabine hydrochloride) and paclitaxel will result in superior progression-free survival. (Detectable Plasma Epstein Barr Virus [EBV] Deoxyribonucleic Acid [DNA] Cohort randomized Phase II) II. To determine whether omitting adjuvant CDDP and 5-FU ...

This study investigates the effects of valaciclovir treatment to individuals with Alzheimer's disease (AD) or Mild Cognitive Impairment of Alzheimer's Disease Type. It is an open pilot trial where 36 participants will receive 4 weeks of oral valaciclovir treatment. To find 36 persons fulfilling inclusion criteria, up to 120 persons ...

In Canada, the most common chronic disease of childhood is asthma. Childhood asthma places a significant burden on the health care system (refn). No objective preschool asthma diagnostic tools exist, and the current gold-standard, the Asthma Predictive Index, does not provide information about lung function and symptom management. In this ...

In France, the prevalence of infectious diseases such as tuberculosis, HIV/HBV/HCV is high amongst migrants originating from certain countries, hence the official guidelines recommending targeted testing. The rapid testing devices (TROD) give immediate results and reduce missed opportunities. However their use is not yet widespread and migrant populations remain insufficiently ...

Option B+ is an innovative strategy pioneered within Malawi that provides universal lifelong ART (tenofovir/lamivudine/efavirenz: TDF/3TC/EFV) for pregnant and breastfeeding women to promote maternal health and prevent HIV transmission to infants. The safety of a TDF/3TC/EFV based regimen used during pregnancy has not been systematically evaluated. Objective 1: To characterize ...

We propose a randomized controlled trial (RCT) of the Skin intervention, compared to an assessment-only condition (both groups receive rapid HIV testing, a review of testing results, and brief HIV prevention counseling) among 350 injection drug users recruited during an acute medical hospitalization at Boston Medical Center. In the general ...

All subjects will receive study drug containing 0.7% cantharidin topical film forming solution. Dermatologic exams, wart counts, measurement of diameter and height of each wart and Evaluation of Response to Treatment (ERT) will be conducted by a qualified member of the research team at Treatment Visits 1, 2, 3 and ...