Home » Clinical Trials »  Search Clinical Trials

Therapeutic Areas:  |  Endocrinology

Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters
 

Metabolic Disorders Clinical Trials

A listing of Metabolic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (18) clinical trials

Doctors at Albert Einstein College of Medicine are seeking healthy volunteers, aged 21-60, to participate in a medical research study to better understand glucose metabolism and brain function. Inclusion Criteria: BP < 130/90 (+-2 meds) BMI < 35 Normal screening labs (CBC, chemistry, lft's PT/PTT) No CAD No first degree ...

Phase

MGTA-456 in Patients With Inherited Metabolic Disorders Undergoing Hematopoietic Stem Cell Transplantation (HSCT)

This phase 2 study is designed to evaluate the safety and efficacy of MGTA-456 after myeloablative conditioning to induce rapid and sustained hematopoietic engraftment with replacement of the specific protein product missing or defective in the patient with an IMD. The study aims to enhance the efficacy of umbilical cord ...

Phase

Metformin in Kidney Disease

Chronic kidney disease (CKD) is a major global health problem associated with substantial costs and resource utilization. Currently, CKD affects more than 500 million people worldwide. Patients with CKD have unacceptably high mortality rates due to cardiovascular (CV) causes, which are not entirely explained by traditional CV risk factors. The ...

Phase

To Investigate the Traditional Chinese Medicine Formula Powder Product in the Treatment of Osteopenia

Osteoporosis is a major public health problem, resulting in potentially pain and increasing risk of fracture. Treatment of osteoporosis consists of pharmacotherapy, lifestyle measures, dietary changes, mineral supplementation. Traditional Chinese medicine is a major component of health care in Taiwan and provides one treatment alternative for osteoporosis. Investigators investigate the ...

Phase

Comparison of A New Technique of Measure of the Insulin Resistance By Scintigraphy With the Reference Technique

Currently, type II diabetes mellitus, has reached epidemic levels in the world. Moreover, the prediction for the year 2030 is even more alarming. Insulin resistance, characterized by a depressed cellular sensitivity to insulin in insulin-sensitive organs, is a central feature of the metabolic syndrome and a risk factor for type ...

Phase

Study to Evaluate the Efficacy of HepaStem in Urea Cycle Disorders Paediatric Patients (HEP002)

The aim of the study is to assess the efficacy of HepaStem treatment in paediatric patients suffering from urea cycle disorders.

Phase

Treosulfan-based Versus Busulfan-based Conditioning in Paediatric Patients With Non-malignant Diseases

The prospective clinical phase II protocol MC-FludT.16/NM is to be conducted to verify safety and efficacy of Treosulfan-based conditioning compared to Busulfan-based conditioning in paediatric patients. Based on the given clinical experience with either Treosulfan-based or Busulfan-based conditioning in combination with Fludarabine no increased risk for graft failure is expected ...

Phase

MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis

This single-institution, phase II study is designed to test the ability to achieve donor hematopoietic engraftment while maintaining low rates of transplant-related mortality (TRM) using busulfan- and fludarabine-based conditioning regimens with busulfan therapeutic drug monitoring (TDM) for patients with various inherited metabolic disorders (IMD) and severe osteopetrosis (OP).

Phase

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT BMT or PBSCT

For some non-malignant diseases (NMD; i.e., thalassemia, sickle cell disease, most immune deficiencies) a hematopoietic stem cell transplant may be curative by healthy donor stem cell engraftment alone. HSCT in patients with NMD differs from that in malignant disorders for two important reasons: 1) these patients are typically nave to ...

Phase

Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide

In this study, the investigators will use functional magnetic resonance imaging (fMRI), a method of imaging the blood flow to parts of the brain, to observe the activity of metabolically-relevant areas of the brain by activating Katp channels in healthy participants and in participants with type 2 diabetes (T2D). All ...

Phase