Metabolic Disorders Clinical Trials

A listing of Metabolic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 114 clinical trials
Delirium Reduction by Volatile Anesthesia in Cardiac Surgery (DELICATE)

Parallel group, prospective, randomized, controlled, single-blinded trial. The aim of our study is to test the hypothesis that volatile anesthesia would reduce the incidence of early postoperative delirium in patients undergoing cardiac surgery with CPB as compared to TIVA.

postoperative delirium
propofol
anesthesia
heart surgery
  • 18 views
  • 07 Oct, 2022
  • 4 locations
Italian Digital Primary Cardiovascular Prevention Study (CV-PREVITAL)

The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular (CV) risk factors (in the short term) and the occurrence of vascular events (in the long term). Promoted …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 29 locations
Evaluating the Metabolic Effects of Dietary NItrate Supplementation for Improving Skeletal Muscle Mitochondrial Function, Insulin Sensitivity, Insulin Secretion, Body Fat Composition and Overall Health (NIMMI)

Dietary nitrate is found to enhance muscle fatty acid oxidation/glucose uptake and increase mitochondrial biogenesis, which in turn, aid in the prevention and management of metabolic diseases

Accepts healthy volunteers
  • 0 views
  • 21 Oct, 2022
  • 1 location
Novel Approaches to Enhance Insulin-sensitizing Effects of Exercise: Targeting PAHSA Metabolism (ETAPA)

Exercise represents an important tool in the prevention and treatment of metabolic disorders associated with obesity and aging, such as type 2 diabetes and cardiovascular disease. Besides

Accepts healthy volunteers
  • 0 views
  • 25 Oct, 2022
  • 1 location
The Effect of Suppression of Adipose Lipolysis on GLP-1 and Energy Intake in Men and Women

Obesity is the outcome of chronic excessive energy intake and reduced energy expenditure leading to energy imbalance. It is a risk factor for many preventable diseases such as metabolic disease

Accepts healthy volunteers
  • 0 views
  • 27 Oct, 2022
  • 1 location
Modulation of Microbiota Metabolism in Cardiac Surgery Patients With at High Risk of Postoperative Multiple Organ Dysfunctions (MMMMODCS)

is a proven risk factor for the development of metabolic disorders of the intestinal flora and bacterial translocation. Previously, it was shown that the change in serum concentrations of phenolic

  • 0 views
  • 14 Oct, 2022
  • 1 location
Time-restricted Eating to Improve Body Fat Mass in Overweight and Obese Individuals With Morning Chronotype: A Randomized, Open-label, Multi-arm Trial

mismatch between the individual chronotype and the social/work life can lead to metabolic disorders. Time-restricted eating (TRE), i.e. energy intake limited to certain windows of time without

  • 0 views
  • 27 Oct, 2022
  • 1 location
Health Benefits of Whole-body Vibration (VIBE-Rx)

The overall goals of this pilot investigation are to determine 1) the feasibility of conducting home based WBV studies, and 2) to determine if sub-acute home based WBV can improve a) exercise capacity, b) conduit- and micro- vascular function, and c) skeletal muscle function.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of LY3561774 in Adults With Mixed Dyslipidemia (PROLONG-ANG3)

This a multicenter, Phase 2b, double-blind, placebo-controlled, parallel group study to provide data on efficacy and safety of LY3561774 administered subcutaneously at various doses in participants with mixed dyslipidemia and on a stable dose of a statin.

fasting
body mass index
hmg-coa reductase inhibitors
  • 0 views
  • 20 Oct, 2022
  • 38 locations
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study With an Open-Label Extension Assessing the Efficacy, Safety, and Pharmacokinetics/Pharmacodynamics of Tirzepatide in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin, or Basal Insulin, or Both (SURPASS-PEDS)

The purpose of this study is to learn more about the safety and efficacy of tirzepatide compared to placebo in children or teenagers with type 2 diabetes taking metformin, or basal insulin, or both. The overall study will last about 60 weeks with up to 14 clinic visits and 6 …

metformin
insulin
type 2 diabetes mellitus
hemoglobin a1c
  • 3 views
  • 20 Oct, 2022
  • 35 locations