Inflammation Clinical Trials

A listing of Inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 809 clinical trials
Featured trial
A Randomized Double-blind Placebo-controlled Parallel Group Study Assessing the Efficacy and Safety of Dupilumab in Patients With Allergic Fungal Rhinosinusitis (AFRS)  

Primary Objective: To evaluate the ability of dupilumab to reduce the need for rescue therapy with systemic corticosteroids (SCS) or surgery of AFRS in patients with AFRS who previously have had sino-nasal surgery Secondary Objectives: To evaluate the efficacy of treatment with dupilumab to reduce sinus opacification in a population …

  • 60 views
  • 09 Nov, 2022
  • 5 locations
Featured trial
Dupilumab in CRSsNP (Liberty CRSsNP ORION)  

To evaluate the effects of dupilumab on transcriptomic signatures associated with CRSsNP and type 2 inflammation To evaluate the effect of dupilumab in the subgroup of participants

congestion
sinus surgery
asthma
nasal congestion
obstruction
  • 20 views
  • 09 Nov, 2022
  • 9 locations
  • 113 views
  • 24 Oct, 2022
  • 98 locations
Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis

clinical safety and efficacy related to improved mucociliary clearance with reduced bacterial colonization as potential drivers of airway obstruction, reduced airway inflammation, exacerbations and mucus

fibrosis
pulmonary function test
macrolides
chest physiotherapy
spirometry
  • 6 views
  • 07 Oct, 2022
  • 16 locations
Safety, Tolerability, and Efficacy of AXA1125 in NASH With Fibrosis

This study will compare the effects of AXA1125, an orally active mixture of amino acids, compared to placebo, on improving fat and inflammation (steatohepatitis) as well as fibrosis in subjects

  • 67 views
  • 07 Oct, 2022
  • 75 locations
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC)

Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe ulcerative colitis will be treated

mercaptopurine
immunomodulators
azathioprine
pancolitis
methotrexate
  • 0 views
  • 07 Oct, 2022
  • 62 locations
A Phase 3 Clinical Trial to Evaluate Efficacy and Safety of Twice-daily Applications of Delgocitinib Cream 20 mg/g Compared With Cream Vehicle for a 16-week Treatment Period in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema (DELTA TEEN)

CHE, such as inflammation. The trial will last up to 22 weeks and has a 1-4 week screening period, a 16 week treatment period and a 2 week follow up period. During the treatment period each

  • 0 views
  • 25 Oct, 2022
  • 11 locations
YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC)

body's immune response to fight cancer and increase the anti-tumor activity of sorafenib and protect and repair the gastrointestinal tract by reducing inflammation and promoting tissue regeneration.

  • 3 views
  • 04 Oct, 2022
  • 20 locations
A Randomized, Double-Blind, Single-Dose, Parallel, Placebo-Controlled Pivotal Trial to Confirm the Efficacy of a Fixed Dose Combination Tablet of Naproxen Sodium and Caffeine to Effectively Alleviate Postsurgical Dental Pain

subsequently have moderate to severe tooth pain. The study treatment naproxen sodium suppresses inflammatory pain by reducing inflammation. In the US, naproxen has been marketed since 1976, and

Accepts healthy volunteers
  • 0 views
  • 24 Oct, 2022
  • 1 location
An Open-Label Rollover Extension Phase 2 Clinical Trial To Evaluate The Long-Term Safety And Efficacy Of KT-301 (Formerly US-APR2020) In Subjects With CKD IV Completing The US-APR2020-01 Study

This is an Open-Label Rollover Extension Clinical Trial to Evaluate the Long-Term Safety and Efficacy of KT-301 (formerly US-APR2020) in Subjects With CKD IV Who Completed the US-APR2020-01 Study

  • 0 views
  • 27 Oct, 2022
  • 5 locations