Hypercalcemia Clinical Trials

A listing of Hypercalcemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 17 clinical trials
Pomalidomide Ixazomib and Dexamethasone With or Without Intensification by Cyclophosphamide in Relapsed or Refractory Multiple Myeloma

The study is designed as a multicenter, non-randomized, Phase II trial with one treatment arm. A total of 82 patients of both genders and older than 18 years with relapsed/refractory multiple myeloma are planned to be included in the study. After the first 6 patients will have finished the first …

alkylating agents
neutrophil count
dexamethasone
bortezomib
cell transplantation
  • 2 views
  • 18 Sep, 2021
  • 18 locations
PTH Analog Type II Odontoid Fracture

This is a prospective cohort study with a historical control group involving patients >=50 years-old with an acute (<3 weeks) Anderson & D'Alonzo type II dens fractures identified on cervical spine CT scan. This will be a pilot efficacy trial to compare treatment of odontoid fractures with 8 weeks of …

  • 0 views
  • 12 Jul, 2022
  • 1 location
A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

The purpose of this study is to evaluate the efficacy of talquetamab in participants with relapsed or refractory multiple myeloma at the recommended Phase 2 dose(s) (RP2Ds) (Part 3).

multiple myeloma
measurable disease
  • 0 views
  • 23 Jul, 2022
  • 63 locations
A Study of Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma

The purpose of this study is to identify recommended Phase 2 doses (RP2Ds) for each treatment combination (between daratumumab plus talquetamab and teclistamab plus daratumumab with or without pomalidomide) and to characterize the safety of each RP2D for selected treatment combinations.

daratumumab
immunomodulatory imide drug
measurable disease
immunoglobulins
human chorionic gonadotropin
  • 114 views
  • 27 Jul, 2022
  • 22 locations
Rapid Normalization of Vitamin D Deficiency in PICU (VITdALIZE-KIDS)

Vitamin D plays an important role in calcium balance, heart and lung health, inflammation, infection prevention, and muscle strength. Due to these roles, it has been suggested that critically ill patients with low vitamin D levels might have higher rates of death and worse long-term health. We believe that identifying …

malnutrition
calcium
cholecalciferol
vitamins
  • 51 views
  • 16 Jun, 2022
  • 10 locations
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria (RICHH)

This study evaluates the efficacy of rifampin in the treatment of hypercalcemia and/or hypercalciuria in participants with biallelic inactivating mutations of the CYP24A1 gene. Eligible subjects

calcium
rifampin
  • 57 views
  • 10 Mar, 2022
  • 1 location
Surgery for Primary Hyperparathyroidism (pHPT) in Patients Older Than 65 Years Compared With Follow-up

General consensus and contemporary guidelines, recommend surgery for primary hyperparathyroidism (pHPT)for all patients below the age of 50, for patients with pronounced hypercalcemia and for

bone mineral density
parathyroid surgery
parathyroid hormones
osteoporosis
renal function
  • 276 views
  • 12 Mar, 2022
  • 1 location
Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma

This phase I trial studies the side effects and best dose of MDM2 Inhibitor KRT-232 when given together with carfilzomib, lenalidomide, and dexamethasone in treating patient with multiple myeloma that has come back (relapsed) or has not responded to previous treatment (refractory). KRT-232 (AMG 232) may stop the growth of …

gilbert's syndrome
monoclonal antibodies
corticosteroids
graft versus host disease
plasmacytoma
  • 27 views
  • 11 Jul, 2022
  • 4 locations
Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy

This study will see if the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during parathyroidectomy (PTx) procedures is better than a surgeon's detection alone. It compares risk-benefits and outcomes in PTx patients where NIRAF detection with PTeye for …

parathyroid
parathyroid hormones
parathyroidectomy
primary hyperparathyroidism
hyperparathyroidism
  • 0 views
  • 21 Mar, 2022
  • 1 location
Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy (NIRAF)

This study describes a single center, randomized, single-blinded clinical trial to assess the clinical benefits of the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during parathyroidectomy (PTx) procedures. It compares risk-benefits and outcomes in PTx patients where NIRAF …

parathyroid
parathyroid hormones
parathyroidectomy
primary hyperparathyroidism
hyperparathyroidism
  • 50 views
  • 19 Apr, 2022
  • 1 location