Friedreich's Ataxia Clinical Trials

A listing of Friedreich's Ataxia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 76 clinical trials
Prevention of Hypertensive Injury to the Brain by Intensive Treatment in IntraCerebral Haemorrhage (PROHIBIT-ICH) (PROHIBIT-ICH)

PROHIBIT-ICH will randomise participants to compare a strategy of intensive BP treatment (target <120/80 mm Hg) guided by telemetric home monitoring, versus standard primary care (current RCP guideline is 130/80 mm Hg), in 112 adult survivors of hypertension-related ICH. The investigators will establish the feasibility and safety of the intervention, …

brain mri
hypertension
prohibit
  • 0 views
  • 03 Feb, 2022
  • 13 locations
Establish a Concordance Between the Mismatch Negativity Amplitude and a Score of Logatoms Discrimination (EVODA-ICMN)

A cochlear implant is a device for the rehabilitation of severe to profound hearing loss. Despite the standardization of surgical procedures and rehabilitation, speech discrimination performance varied significantly in cochlear implant users and could be improved by early individualized cares. However, there is no objective method yet to evaluate phonemes …

  • 0 views
  • 25 Mar, 2022
  • 1 location
Assessment of the Efficacy of Lenvatinib Versus Sorafenib in the Management of Advanced Hepatocellular Carcinoma

Hepatocellular carcinoma is the most common type of liver cancer, which is the 3rd leading cause of cancer deaths worldwide. The incidence is expected to increase as a consequence of chronic liver disease with its multiple risk factors, including chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, …

tyrosine
cancer
TACE
erlotinib
  • 0 views
  • 02 Jun, 2022
  • 1 location
Cortical Network Modulation by Subthalamic Nucleus DBS

Deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson's disease (PD) can provide substantial motor benefit yet can also produce unwanted mood and cognitive side effects. Although the neural mechanisms underlying benefits and side effects are not well understood, current hypotheses center on the potentially measurable yet currently …

Accepts healthy volunteers
brain stimulation
  • 0 views
  • 15 Jun, 2022
  • 1 location
Characterization of the Cardiac Phenotype of Friedreich's Ataxia (FRDA)

Friedreich's ataxia (FRDA) is an autosomal recessive disease characterized by loss of coordination and cardiomyopathy. It is the most common form of inherited ataxia with an incidence in 1

stress test
heart disease
diabetes
Accepts healthy volunteers
ejection fraction
  • 0 views
  • 07 Oct, 2022
  • 2 locations
A Natural History Study to TRACK Brain and Spinal Cord Changes in Individuals With Friedreich Ataxia (TRACK-FA) ((TRACK-FA))

This is a natural history study prospectively investigating neuroimaging markers of disease progression in children and adults with Friedreich ataxia (FA). There will be three assessment periods

spinal cord
Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 5 locations
Imaging of Uveitis Patients Receiving Injectable Fluocinolone Acetonide Implant (PANTHER)

We will prospectively observe patients with uveitis who are either active or were recently active in the previous 6 months and are treated with the i-FA implant. All of the patients will have

fluocinolone
  • 7 views
  • 13 May, 2022
  • 1 location
FA Clinical Outcome Measures (FA-COMS)

study will lead to the development of valid yet sensitive clinical measures crucial to outcome assessment of patients with Friedreich's Ataxia. This study will support genetic modifier studies

genetic testing
Accepts healthy volunteers
  • 467 views
  • 11 May, 2022
  • 14 locations
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study

. Carriers of IBMFS pathogenic variant(s) are at increased risk of cancer. The prototype disorder is Fanconi's Anemia (FA); other IBMFS will also be studied. Objectives

dyskeratosis congenita
fanconi's syndrome
shwachman-diamond syndrome
fanca
pure red cell aplasia
  • 43 views
  • 24 Oct, 2022
  • 2 locations
Molecular Basis of Food Allergy

The Study examines the molecular basis of food allergy. It explores the interaction between T cells, InKT cells and cytokines in the development of food allergy. The study also explores these factors in development of tolerance "outgrowing" food allergy. It will also explore the genetic factors that lead to the …

atopy
eosinophilic esophagitis
cytokines
  • 49 views
  • 05 Jan, 2022
  • 1 location