Friedreich's Ataxia Clinical Trials

A listing of Friedreich's Ataxia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 76 clinical trials
Study of a Latanoprost Ocular Implant for Treatment of Open Angle Glaucoma or Ocular Hypertension.

This is an open label, single dose (100 ng/day) study to assess the safety, tolerability and biodegradation of the PA5436 Latanoprost FA SR Ocular Implant in adults who have OAG or OHT.

corrected visual acuity
hypertension
retinopathy
glaucoma
prostaglandin
  • 0 views
  • 03 May, 2022
  • 2 locations
A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer. (NAUTICALCRC)

Encorafenib is currently being developed (with or without binimetinib), in combination with cetuximab, for the treatment of adult patients with B-RAF proto-oncogene, serine/threonine kinase V600E mutant (BRAF V600E) metastatic colorectal cancer (mCRC), who have received prior systemic therapy.

  • 0 views
  • 07 Oct, 2022
  • 31 locations
T Cell Receptor α/β TCD HCT in Patients With Fanconi Anemia

This is a phase II trial of T cell receptor alpha/beta depletion (/ TCD) hematopoietic cell transplantation (HCT) transplantation in patients with Fanconi anemia (FA) to eliminate the need for

total body irradiation
hla-a
rituximab
karnofsky performance status
busulfan
  • 26 views
  • 01 Feb, 2022
  • 1 location
HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

Fanconi Anemia (FA). Patients will undergo a transplant utilizing mis-matched related or matched unrelated donors following a preparative regimen of busulfan, fludarabine, anti-thymocyte globulin and

busulfan
rabbit atg
anemia
serum bilirubin level
fanca
  • 76 views
  • 21 Apr, 2022
  • 2 locations
Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients With Hospital-acquired Pneumonia. (SHARP)

FILMARRAY® Pneumonia Panel (FA-PP, bioMérieux) is an automated diagnostic device, allowing detection of multiple pathogens and resistance markers in one hour. Strategies combining rapid diagnostic testing

x ray
superinfections
fever
antibiotics
leukocytosis
  • 0 views
  • 07 Oct, 2022
  • 2 locations
Treatment of Class II Malocclusion With Excessive Overjet

performed with a removable functional appliance, Headgear Activator (HGA). Treatment starting in early adolescence is performed with fixed orthodontic appliance (FA). The hypotheses are:

  • 0 views
  • 21 Mar, 2021
  • 1 location
Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation

Palmitoylethanolamide (PEA), a non-psychoactive cannabis compound derived from peanuts, egg yolks, and soybeans, is an Endogenous FA Amide produced in the body as a biological response and a

fracture fixation
Accepts healthy volunteers
  • 0 views
  • 21 Apr, 2022
  • 1 location
Quercetin Chemoprevention for Squamous Cell Carcinoma in Patients With Fanconi Anemia

Fanconi anemia (FA) is an autosomal recessive disease characterized by progressive bone marrow failure, variable congenital abnormalities and a predisposition to malignancy, particularly acute

graft versus host disease
fanconi syndrome
quercetin
pancytopenia
cancer
  • 24 views
  • 25 Mar, 2022
  • 1 location
Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction

abstinence, participants will present to the inpatient CHPS the day prior to the scheduled scan and stay overnight. The 2-[18F]-FA PET/CT brain scans will consist of an injection followed by an 7-hour

Accepts healthy volunteers
  • 19 views
  • 22 Mar, 2022
  • 1 location
Assessment of the Link Between Monomeric Functional Form Plasma Level of Vasostatin-1 and Occurrence of New Onset Atrial Fibrillation in Severe Intensive Care Patients (TVASORYTHM)

ventricular filling in diastole time, on the other hand the FA is responsible for an over-risk of ischemic stroke. In fact, it has been shown that the occurrence of new onset AF in intensive care is

shock
arrhythmia
fibrillation
systemic inflammatory response syndrome
catecholamines
  • 48 views
  • 04 Oct, 2022
  • 1 location