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Acute Pain Clinical Trials

A listing of Acute Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (75) clinical trials

Is PECS Block Equivalent to Paravertebral Block in Preventing Postoperative Pain After Breast Surgery?

Aim of the study is to compare paravertebral block and PECS block success rate in patients undergoing elective breast surgery (mastectomy or quadrantectomy) with a combined anesthesia technique. Primary outcome is block success rate defined as a VAS score of 30 or less in PACU and at 6, 12 and ...

Phase

Liposome Bupivacaine in Interscalene Block for Rotator Cuff Repair

All patients will receive preoperative oral multimodal medications consisting of acetaminophen 975 mg, gabapentin 300 mg, and Celebrex 400 mg. After completion of the preoperative process the patient will be placed in the supine position with the head of the bed elevated 30 degrees with standard ASA monitors applied. Sedation ...

Phase

Intranasal Dexmedetomidine Sedation and Analgesia During Pediatric Emergency Room Procedures

The study objective is to determine if intranasal dexmedetomidine is a safe and effective sedative drug during small painful procedures in the pediatric emergency room. Patients of the pediatric emergency room at Oulu university hospital with any medical condition requiring a small painful procedure like i.v. cannulation or lumbar puncture ...

Phase

Procedural Pain Treatment With Transmucosal Sublingual Fentanyl Tablet in Colonoscopy Patients

The purpose of this study is to evaluate the efficacy of fentanyl transmucosal tablet to placebo in patients having colonoscopy. Fentanyl is a highly lipophilic drug absorbed very rapidly through the oral mucosa and more slowly through the gastrointestinal tract. Orally administered fentanyl undergoes pronounced hepatic and intestinal first pass ...

Phase

Randomized Double-blind Placebo Controlled Cross Over Design Topical Morphine for Analgesia in Pediatric Procedures

The use of an opioid such as morphine topical gel 30 minutes before a procedure would be effective in reducing pain in children. It has proven effective analgesic with minimal adverse effects, especially in children older than 6 months, and even its use is authorized in young children.

Phase

Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

Study Design: Prospective study of 58 subjects undergoing elective Lumbar Spinal Fusion (1-3 levels- posterior approach) at UTSW Zale Lipshy University Hospital with: Continuous Lumbar Epidural Analgesia (Patient-Controlled Epidural Analgesia- PCEA groups) Intravenous Patient-Controlled Analgesia (IV PCA) Study Interventions - The intervention to be evaluated in this study is epidural ...

Phase

Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium

Delirium is a state of acutely occurred and transient cerebral dysfunction. It is a common complication in elderly patients after surgery. A systematic review showed that an average of 36.8% (range 0 to 73.5%) of surgical patients developed postoperative delirium, and its occurrence increased with age. According to our previous ...

Phase

Lidocaine vs Ketorolac for Management of Renal Colic in the Emergency Department

The hypothesis of the study is that lidocaine will be as effective as ketorolac in decreasing patient's perception of pain as measured by the 10 point Visual Analogue Scale (VAS). The aim of the study is to compare the safety & efficacy of lidocaine versus ketorolac for acute pain secondary ...

Phase

Pre-emptive Opioid Treatment to Prevent Rebound Pain After Arthroscopic Rotator Cuff Repair and/or Acromioplasty Under General Anesthesia and Interscalene Block

Arthroscopic shoulder rotator cuff repair and acromioplasty are associated with severe postoperative pain. The interscalene block (ISB) is commonly used for this type of surgery, providing analgesia by anesthetizing the nerves that supply the shoulder. Although the nerve block provides extremely effective analgesia for the first 6-8 hours, patients experience ...

Phase

Methadone and Interscalene Block for Shoulder Surgery

Shoulder surgery is one of the most common orthopedic operations, with 1.4 million procedures performed worldwide. Advances in surgical technology now allow the majority of these procedures to be performed arthroscopically. A growing number of shoulder arthroscopic procedures are now conducted on an outpatient basis. Effective pain control is therefore ...

Phase