Acute Pain Clinical Trials

A listing of Acute Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 43 clinical trials
Intravenous (IV) Hydrocortisone for TKA (Total Knee Arthroplasty)

In this study, total knee replacement patients will be determined to be stiff or non-stiff preoperatively. Stiffness designation is determined by preoperative range of motion (if flexion is < 100 degrees, or extension lag is > 10 degrees). The stiff and non-stiff groups will both be randomized to two groups …

range of motion
stiffness
postoperative pain
anesthesia
osteoarthritis
  • 34 views
  • 18 Jan, 2022
  • 1 location
Efficacy and Safety of Dexmedetomidine in the Analgesic Prophylaxis in Patients Undergoing Cardiovascular Surgery

Acute pain is one of the complications after cardiothoracic surgeries . It can delay patientsrecovery and may increase patientsmorbity and mortality. This study intends to evaluate

sedative
analgesia
pain relieving
anesthesia
cardiopulmonary bypass
  • 0 views
  • 28 Oct, 2021
  • 2 locations
Regional Blocks for Lateral Condyle Fractures

The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning. Patients will be randomized into one of two groups. Group 1 will receive an infraclavicular nerve block to the affected extremity by a …

ropivacaine
postoperative pain
analgesia
nerve block
pain relieving
  • 14 views
  • 08 May, 2021
  • 1 location
Intranasal Dexmedetomidine Sedation and Analgesia During Pediatric Emergency Room Procedures

The study objective is to determine if intranasal dexmedetomidine is a safe and effective sedative drug during small painful procedures in the pediatric emergency room. Patients of the pediatric emergency room at Oulu university hospital with any medical condition requiring a small painful procedure like i.v. cannulation or lumbar puncture …

sedative
analgesia
pain relieving
dexmedetomidine
  • 20 views
  • 21 May, 2021
  • 1 location
Betamethasone (Betapred ) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy

Betamethasone is currently given routinely in conjunction with tonsillectomy surgery at the majority of Ear, Nose & Throat clinics in Sweden. The scientific evidence regarding the effects of betamethasone in adults is limited when it comes to postoperative nausea (PONV), pain and postoperative bleeding.

tonsillectomy
vomiting
nausea
postoperative nausea
betamethason sodium phosphate
  • 0 views
  • 24 Jan, 2021
  • 1 location
Predicting, Understanding and Speeding Recovery After TKA

The objective of this research study is to better understand patterns of recovery after Total Knee Arthroplasty (TKA). The study will evaluate how pain, activity and cognitive (i.e., thinking style) responses determine patterns of recovery, and the study will evaluate the efficacy of gabapentin versus placebo for improving recovery after …

total knee replacement
gabapentin
  • 65 views
  • 27 Jan, 2022
  • 1 location
Pregabalin vs. Gabapentin on Reducing Opioid Usage

This is a single-center, randomized, open-label, Phase 4 clinical trial investigating the efficacy of multiple-dose administrations of Pregabalin or Gabapentin in combination with traditional opioid pain medications to decrease the amount of opioid pain medication usage in single-system orthopedic trauma patients.

pregabalin
opioid
gabapentin
  • 4 views
  • 13 Aug, 2021
  • 1 location
Simultaneous RZV and aIIV4 Vaccination

The overall aim of the study is to compare the safety of simultaneous RZV (SHINGRIX) and inactivated adjuvanted influenza vaccine aIIV4 (FLUAD) versus simultaneous RZV (SHINGRIX) and inactivated influenza HD-IIV4 (Fluzone HD) vaccine in persons 65 years. A prospective, randomized, blinded clinical trial that will be conducted during the 2021/2022 …

  • 0 views
  • 30 Sep, 2021
  • 1 location
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study

This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID vaccine either simultaneously or sequentially, 14 days apart. A second dose of mRNA COVID vaccine will be administered either 3 or 4 weeks following …

Accepts healthy volunteers
  • 0 views
  • 29 Nov, 2021
  • 3 locations
EUS-Coeliac Plexus Block Versus Radiofrequency Ablation in Pain Relief of Patients With Malignancy

Many cancer patients suffer from intractable pain and which is often suboptimally controlled by even strong opioid analgesics. Coeliac plexus neurolysis (CPN) is procedure which intended to permanently destroy the nociceptive pathway that transmits the pain caused by the tumour. It can be with different approaches, such as percutaneously guided …

  • 0 views
  • 01 Apr, 2021
  • 1 location