Acute Pain Clinical Trials

A listing of Acute Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 46 clinical trials
The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement

. Neuropathic pain medications, such as venlafaxine are effective in managing nerve pain. Recent studies also support its potential role in acute pain management. Here, we propose a prospective randomized

total knee replacement
anesthesia
nerve block
opioid
acute pain
  • 0 views
  • 25 Jul, 2022
  • 1 location
Sufentanil Intranasal

Study of the effects of intranasal sufentanil on patients presenting to the emergency department with acute post-traumatic pain.

sufentanil
  • 0 views
  • 25 Feb, 2022
  • 1 location
Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKA

In this study we wish to investigate the analgesic effect 3 different nerve block regimes in patients following primary total knee arthroplasty (TKA). All nerve blocks were performed as single shot blocks with the administration of Marcain 5 mg/ml. Regime A: proximal Femoral Triangle Block (FTB) with 10 ml including …

  • 0 views
  • 15 May, 2022
Pharmacokinetic Analysis of Bupivacaine in the Presence and Absence of Perineural Dexamethasone in Axillary Blockade

The investigators will conduct a prospective, randomized, double-blinded study using an axillary brachial plexus block in patients undergoing elective surgery of the distal forearm and hand to characterize and describe the pharmacokinetics of bupivacaine associated with perineural dexamethasone. The pharmacokinetic analysis will be performed by measuring bupivacaine plasma levels at …

  • 0 views
  • 29 Jul, 2022
  • 1 location
Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED

In the situation when intravenous access is not readily available or unobtainable, sub-dissociative dose ketamine can be administered via intranasal route (IN). The data supporting intranasal route in pediatric patients is somewhat conflicting with regards to the optimum intranasal dose (range 0.75-1 mg/kg) and frequencies of administration. Hence, another non-invasive …

ketamine
analgesics
back pain
acute pain
analgesia
  • 8 views
  • 23 Apr, 2022
  • 1 location
Improving Pain Management and Decreasing LOS After Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA)

This two arm, patient blinded, randomized, post market clinical trial in a single orthopedic hospital will determine whether there is improved pain management and decreased length of stay when comparing standard of care pain management with and without sufentanil.

sufentanil
diabetes
pain relieving
  • 0 views
  • 08 Apr, 2022
  • 1 location
The Effect of Pretreatment With Intravenous Lidocaine for Intravenous Contrast:

Intravenous contrast media is commonly used for CT scans for improved image clarity in pediatric emergency medicine. Children who feel discomfort during the administration of IV contrast media may not remain still during the CT scan, which affects the overall study quality and reliability. Therefore, many young patients often undergo …

lidocaine
pain assessment
premedication
discomfort
  • 0 views
  • 23 Mar, 2022
  • 1 location
Comparison of Nebulized Ketamine to Intravenous Sub-Dissociative Dose Ketamine for Pain

double-blind trial of 120 adult patients that evaluated analgesic efficacy and safety of nebulized ketamine at three different dosing regimens for acute pain in the ED. Currently, we are conducting two

ketamine
hyperalgesia
anesthesia
cancer pain
pain relief
  • 56 views
  • 01 Nov, 2021
  • 1 location
Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures

I. Background: Patients with multiple rib fractures are challenging from both pulmonary and analgesia perspectives. Adequate pain management is essential in prevention of complications secondary to decreased inspiratory volume. Significant morbidity and mortality of rib fractures is secondary to severe pain that limits ribcage movement, decreases inspiratory volumes and causes …

opiates
ketamine
analgesia
pain relieving
  • 0 views
  • 28 Nov, 2021
  • 1 location
Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain

Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for more than 6 months will be enrolled in this clinical trial. Aim: Define the attributable pain relief and functional improvement in participants with PLP/RLP after contralateral limb sciatic nerve block. Also, contribute to the basic science …

amputation of the lower limb
transcutaneous electrical nerve stimulation
limb pain
nerve block
lidocaine
  • 0 views
  • 11 Dec, 2021
  • 1 location