Acute Pain Clinical Trials

A listing of Acute Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 23 clinical trials
Opioid Prescription After Cesarean Trial

Non-inferiority randomized trial of 5,500 women with a cesarean delivery randomized prior to discharge to either an individualized opioid prescription protocol (IOPP) that includes shared decision making or to a fixed opioid prescription of 20 tablets of oxycodone 5mg.

cesarean section
oxycodone
opioid
  • 97 views
  • 16 Jun, 2021
  • 10 locations
Standard of Care Therapy With or Without Stereotactic Radiosurgery and/or Surgery in Treating Patients With Limited Metastatic Breast Cancer

This randomized phase II/III trial studies how well standard of care therapy with stereotactic radiosurgery and/or surgery works and compares it to standard of care therapy alone in treating patients with breast cancer that has spread to one or two locations in the body (limited metastatic) that are previously untreated. …

epinephrine
neutrophil count
computed tomography
absolute neutrophil count
ct scan
  • 574 views
  • 09 Jun, 2021
  • 84 locations
Paracetamol UNIFLASH for Buccal Use Phase III Trial in Acute Pain Due to a Tooth Extraction

This study aims to evaluate the analgesic efficacy of single dose of a new paracetamol formulation (paracetamol UNIFLASH) for buccal use in comparison to two different doses of an oral paracetamol form controlled versus placebo.

acute pain
moderate pain
  • 0 views
  • 11 Jun, 2021
  • 13 locations
Erector Spinae Block Versus Surgeon Infiltration in VATS Procedures

The study is comparing the difference between erector spinae block and surgeon infiltration after VATS (Video Assisted Thoracoscopic Surgery). The outcomes measured are pain scores, opioid usage, opioid side effects, and patient satisfaction.We are also also studying the effectiveness of liposomal bupivacaine (EXPAREL) in a block by randomizing patients to …

opioid
anesthesia
thoracoscopic surgery
exparel
bupivacaine
  • 240 views
  • 13 Jun, 2021
  • 1 location
Dexmedetomidine in TAP Block for Inguinal Hernia Repair

This prospective double-blind randomized study will aim at evaluating the short- and long-term postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane (TAP) block with a combination of local anesthetic and dexmedetomidine in inguinal hernia repair under general anesthesia

elective surgery
dexmedetomidine
local anesthetic
anesthesia
local anesthetics
  • 0 views
  • 16 Jun, 2021
  • 1 location
Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

To determine whether the addition of erector spinae plane (ESP) catheters to existing multimodal analgesic regimen with intrathecal morphine provides superior postoperative analgesia in patients undergoing hepatic resection compared with patients not receiving ESP catheters.

morphine
analgesia
pain relieving
ropivacaine
  • 0 views
  • 05 Jun, 2021
  • 1 location
Adjunct VR Pain Management in Acute Brain Injury

Severe and refractory pain after acute injury is a known-risk factor for chronic opioid use disorder. In this study, the investigators will use Virtual Reality (VR) immersion as a non-pharmacological adjunct to treat pain associated with acute traumatic injuries, including traumatic brain injury. The investigators hypothesize that VR therapy will …

traumatic brain injury
injuries
moderate pain
coma
opioid use
  • 0 views
  • 16 Jun, 2021
  • 2 locations
Enhancing Medication-based Analgesia in Humans- STUDY 2

This research is being done to evaluate whether combining medications that are FDA approved but have not yet been approved for combination treatment, can be an effective way to reduce pain. This is study 2 is a series of studies.

analgesia
pain relieving
opioid
  • 67 views
  • 16 Jun, 2021
  • 1 location
Pilot Investigation to Evaluate FlowOx2.0 for Experimental Treatment of Spasticity

This is a descriptive, prospective, non-controlled clinical investigation to be conducted on approximately 10 enrolled subjects at one site at Haukeland University Hospital in Bergen, Norway. The target subjects are male or female, 18-70 years, diagnosed with MS according to revised McDonald criteria (9) with spasticity and pain associated with …

spasticity
  • 0 views
  • 05 Jun, 2021
  • 1 location
Intravenous Gammaglobulin for Sickle Cell Pain Crises

The purpose of this study is to determine whether intravenous immune globulin is safe and effective in the acute treatment of pain crises in sickle cell disease. Funding Source: Food and Drug Administration (FDA), Office of Orphan Products Development (OOPD)

narcotics
acute pain
thalassemia
  • 21 views
  • 16 Jun, 2021
  • 1 location