Low Blood Pressure (Hypotension) Clinical Trials

A listing of Low Blood Pressure (Hypotension) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 30 clinical trials
Norepinephrine vs Phenylephrine During General Anesthesia

50 million patients undergo surgery each year in the United States. Postoperative mortality is considered the third leading cause of death worldwide. Hypotension during surgery have been linked to increased postoperative morbidity and mortality. Episodes of hypotension during surgery are associated with an increased risk of acute kidney injury, stroke, …

stroke
vasopressor
  • 0 views
  • 19 Jul, 2021
  • 5 locations
Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia

Hypotension is frequently encountered after induction of general anesthesia. It can be pronounced in elderly patients and can require administration of vasopressor agents including ephedrine and phenylephrine. Intraoperative hypotension, especially prolonged episodes, can contribute to an increase in morbidity and mortality in the postoperative period as suggested by some former …

ephedrine
intraoperative hypotension
vasoconstrictor
anesthesia
  • 392 views
  • 23 Jan, 2021
  • 1 location
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV

The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased blood pressure in the pediatric population, 12 to 16 year old patients undergoing general and neuraxial anesthesia. The secondary objectives are to describe changes in blood pressure …

anesthesia
diabetes
  • 118 views
  • 25 Jul, 2021
  • 10 locations
Title: Effects of Ephedrine Phenylephrine and Norepinephrine on Contractility of Human Myometrium and Umbilical Arteries: An In-vitro Study

Hypotension is one of the most common adverse effects of spinal anesthesia for cesarean deliveries, affecting as many as 55-90% of mothers. Hypotension during cesarean deliveries can have detrimental effects on the mother and neonate. Various vasopressors, such as ephedrine, phenylephrine and more recently norepinephrine, have been used for the …

cesarean section
anesthesia
ephedrine
norepinephrine
vasoconstrictor
  • 6 views
  • 12 Mar, 2021
  • 1 location
The Effect of Ondansetron on Spinal Anesthesia in Caesarean Section

The purpose of this study is to compare the administration of two different doses of ondansetron to placebo to prevent hypotension and bradycardia following spinal anaesthesia. Apart from haemodynamic parameters (blood pressure and heart rate),characters of the spinal blockage (time of onset and regression) will be recorded too.

ondansetron
cesarean section
anesthesia
  • 1 views
  • 30 Jan, 2021
  • 1 location
Control Mean Arterial Pressure in the Intensive Care Unit

The goal of this randomized controlled trial is to compare two different strategies of postoperative mean arterial pressure (MAP) management (manual versus automated) in patients who underwent a major surgery and admitted in the intensive care unit or post-anesthesia care unit for postoperative care. The investigators hypothesis is that the …

  • 0 views
  • 28 Jan, 2021
  • 2 locations
Noninvasive Continuous Blood Pressure Monitoring for Cesarean Delivery

Noninvasive continuous blood pressure monitoring for preventing post-spinal hypotension during cesarean delivery: A randomized controlled trial

  • 0 views
  • 15 May, 2021
  • 1 location
The Hemodynamic Effects of Vasopressin in Patients With Fontan Physiology

The goal of this study is to evaluate if vasopressin can elevate systemic arterial blood pressures without having a significant effect on pulmonary arterial pressures. Because patients who have undergone Fontan procedures rely on low pressures across the pulmonary vascular bed to maintain cardiac output, vasoactive agents that concomitantly increase …

vasopressin
  • 0 views
  • 25 Jan, 2021
  • 2 locations
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

Compression garments have been shown to be effective in the treatment of orthostatic hypotension in autonomic failure patients. The purpose of this study is to determine the hemodynamic mechanisms by which abdominal compression (up to 40 mm Hg) improve the standing blood pressure and orthostatic tolerance in these patients, and …

parkinson's disease
atrophy
multiple system atrophy
pure autonomic failure
midodrine
  • 99 views
  • 03 Feb, 2021
  • 1 location
Development of Advanced Double Intravenous Vasopressor Automated (ADIVA) System

Maternal hypotension during spinal anaesthesia for Caesarean delivery may bring various adverse effects. It is therefore important to closely monitor hypotension during spinal anaesthesia, however current technology does not allow the blood pressure monitoring to respond in timely manner should there be any occurrence of hypotension. The investigators developed an …

elective cesarean delivery
ephedrine
vasopressor
vasoconstrictor
maternal hypotension
  • 28 views
  • 27 Jan, 2021
  • 1 location