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Low Blood Pressure (Hypotension) Clinical Trials

A listing of Low Blood Pressure (Hypotension) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (37) clinical trials

Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV

This is a Phase 4 multi-center, randomized open-label study in 100 subjects aged 12 to 16 years who experience a decrease in blood pressure during a procedure requiring general or neuraxial anesthesia. At least 300 subjects will be enrolled in this study. It is anticipated that up to 33% of ...


Fluid Responsiveness Evaluation in Sepsis-associated Hypotension

Multi-center randomized study comparing dynamic assessment of fluid responsiveness utilizing Starling SV monitor compared to a control group. Subjects will be randomized in a 2:1 treatment to control group ratio to increase power for sub-analysis by patient population. Patients randomized to the Starling SV arm will have treatment guided by ...


A Randomized Double-Blind Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis

Anaphylaxis is a severe systemic reaction caused by release of mediators from mast cells and basophils. Manifestations include cutaneous, respiratory, cardiovascular, or gastrointestinal signs and symptoms. Although anaphylaxis is frequently attributed to exposure to specific foods, drugs, and insect venoms in sensitive individuals, a causative factor is not identified in ...


Pharmacokinetic and Pharmacodynamic Effects of MTR107 in End-Stage Renal Disease (ESRD) Patients

The present clinical trial aims to investigate and provide a more precise characterization of the pharmacokinetic and pharmacodynamic profile of MTR107 in a population of ESRD patients predisposed to developing intradialytic hypotension. The study is also designed as a dose esclating study aiming to assess MTR107 safety.


Phenylephrine in Spinal Anesthesia in Preeclamptic Patients

The study will be approved by the Northwestern University Institutional Review Board. Eligible women admitted to the Labor and Delivery Unit of Prentice Women's Hospital will be approached for study participation immediately after the routine preanesthetic evaluation. This usually occurs shortly after admission to the Labor and Delivery Unit. Women ...

Phase N/A

Effects of Transitional Circulation in ELBW Infants

Screening Phase: The subject's parents/guardians/LAR will be approached if the infant's birth weight makes them eligible for this research study. Study Phase: During this study, we will use the monitoring methods normally used in the Neonatal Intensive Care Unit (NICU) and some new monitoring methods to find out all the ...

Phase N/A

Preventive Effect of Leg Wrapping Combined With Trendelenburg Position on Hypotension Induced by Propofol

** Study procedure check baseline blood pressure ( systolic, diastolic, mean) and heart rate. apply pre-defined measures to each group(arm) ( summarized in arms and interventions section ) induction using propofol 2mg/kg After bispectral index (BIS) goes below 60 & patient become unconsciousness, inject rocuronium 0.6mg/kg intubate patient between 3 ...

Phase N/A

Point of Care Ultrasonography In The Management of Undifferentiated Shock: A Pilot Randomized Controlled Trial

This project aims to determine the feasibility of conducting a randomized controlled trial investigating point of care ultrasound guided resuscitation compared with usual care in the management of undifferentiated shock at the Critical Care Trauma Centre (CCTC) in London Health Science Centre (LHSC).

Phase N/A

Midodrine for the Treatment of Refractory Hypotension

Persistent hypotension in critically ill patients remains a major barrier to discharging patients from the intensive care unit (ICU). In our hospital, in patients with adequate tissue perfusion, midodrine has been observed to treat hypotension in order to wean continuous intravenous (IV) vasopressors and therefore promote ICU discharge. There are ...


Vasopressor SAT Study

This observational study will compare mean arterial pressure and vasoactive drug dose recorded at two time points: prior to awakening from sedation during the awakening from sedation trial The vasoactive infusion will be titrated to a mean arterial pressure as determined by the medical team prior to study enrollment. Each ...

Phase N/A