Hematologic Neoplasms Clinical Trials

A listing of Hematologic Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 64 clinical trials
A Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants With Hematologic Malignancies and Various Regimens of Immunosuppression and in Participants With Solid Tumors on PD1/PDL1 Inhibitor Therapy

> Adults ages 18 and older who have a solid tumor or blood cancer and who may benefit from a vaccine that might prepare their immune system for fighting and preventing infection from COVID-19

cancer
acute leukemia
neutrophil count
multiple myeloma
lymphoma
  • 0 views
  • 12 Sep, 2021
  • 1 location
Donor Stem Cell Transplant With Treosulfan Fludarabine and Total-Body Irradiation for the Treatment of Hematological Malignancies

This phase II trial studies how well a donor stem cell transplant, treosulfan, fludarabine, and total-body irradiation work in treating patients with blood cancers (hematological malignancies

transplant conditioning
carbon monoxide
high grade lymphoma
remission
apheresis
  • 0 views
  • 17 Sep, 2021
  • 1 location
GVHD Prophylaxis With Methotrexate in Haploidentical HCT Using Posttransplant Cyclophosphamide

evaluating this drug in adult patients with hematologic malignancies undergoing haploidentical HCT with posttransplant cyclophosphamide.

mycophenolate
cyclophosphamide
leukemia
lymphoma
remission
  • 0 views
  • 23 Sep, 2021
  • 2 locations
A Study to Evaluate the Safety PK and PD of APG-2575 in Patients With Hematologic Malignancies

The purpose of this study is to assess the safety, tolerability, pharmacokinetic and pharmacodynamic properties of APG-2575 in patients with relapse or refractory chronic lymphocytic leukemia and non-hodgkin's lymphoma.

cancer
mantle cell lymphoma
lymphoid leukemia
neutrophil count
leukemia
  • 1 views
  • 18 Sep, 2021
  • 3 locations
Thrombosomes in Bleeding Thrombocytopenic Patients Study

This prospective, multicenter, randomized, open-label, Phase 2, parallel, dose ranging, multidose trial will enroll patients into 3 Thrombosomes dose groups and 1 control liquid stored platelets (LSP) group in order to evaluate, in a dose-escalation manner, the safety, and impact on bleeding, and the preliminary effect on coagulation measures of …

myeloproliferative disorder
myeloproliferative neoplasm
hematologic malignancy
platelet transfusion
  • 0 views
  • 17 Sep, 2021
  • 5 locations
Ustekinumab for the Prevention of Acute Graft Versus Host Disease After Unrelated Donor Hematopoietic Cell Transplant

This phase II trial studies how well ustekinumab works in preventing acute graft versus host disease after unrelated donor hematopoietic cell transplant. Sometimes the transplanted cells from a donor can attack the body's normal tissues (called graft-versus-host disease). Giving ustekinumab after the transplant may help prevent acute graft versus host …

carbon monoxide
ejection fraction
mobilized
hematologic malignancy
graft versus host disease
  • 0 views
  • 20 Sep, 2021
  • 4 locations
Symptom Management for YA Cancer Survivors

Symptom interference is common for survivors of young adult cancer (aged 18-39 at diagnosis) and impacts their abilities to achieve normative life goals (e.g., education, careers, independence, romantic/social relationships) as well as adhere to recommended follow-up care. Assistance with symptom management has been rated by young adult survivors as an …

cancer
germ cell tumors
primary cancer
endocrine cancers
  • 0 views
  • 24 Sep, 2021
  • 1 location
Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization

This phase Ib/II trial studies the side effects and best dose of ibrutinib and how well it works in treating patients with COVID-19 requiring hospitalization. Ibrutinib may help improve COVID-19 symptoms by lessening the inflammatory response in the lungs, while preserving overall immune function. This may reduce the need to …

cancer
growth factor
neutrophil count
absolute neutrophil count
ibrutinib
  • 0 views
  • 18 Sep, 2021
  • 1 location
(Apex) CGT9486 in Patients With Advanced Systemic Mastocytosis

with Associated Hematologic Neoplasm (SM-AHN), and Mast Cell Leukemia (MCL).

  • 0 views
  • 23 Sep, 2021
  • 5 locations
Selpercatinib for the Treatment of Advanced Solid Tumors Lymphomas or Histiocytic Disorders With Activating RET Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well selpercatinib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphomas, or histiocytic disorders that have activating RET gene alterations. Selpercatinib may block the growth of cancer cells that have specific genetic changes …

solid tumor
MRI
growth factor
pegfilgrastim
tumor markers
  • 18 views
  • 12 Sep, 2021
  • 90 locations