Hematologic Neoplasms Clinical Trials

A listing of Hematologic Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 7 clinical trials
Combination of Baricitinib and Adalimumab in Rheumatoid Arthritis

As stated by the European League Against Rheumatism (EULAR) and the Societe Francaise de Rhumatologie (SFR), treatment of patients with rheumatoid arthritis (RA) should target sustained remission or at least low disease activity. However, despite significant advances based on various combinations of conventional synthetic disease-modifying antirheumatic drugs (DMARDs) and biologic …

adalimumab
abatacept
anakinra
tofacitinib
methotrexate
  • 0 views
  • 21 Jul, 2021
  • 20 locations
Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

This early phase I trial is to find out the effect of adding cord blood tissue-derived mesenchymal stromal cells (cb-MSCs) to ruxolitinib in treating patients with acute graft versus host disease that does not respond to steroid therapy (steroid-refractory). Ruxolitinib may stop the growth of cancer cells by blocking some …

donor lymphocyte infusion
cell transplantation
graft versus host disease
acute graft versus host disease
cancer
  • 0 views
  • 26 Jul, 2021
  • 1 location
Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback

-HSCT in children and young adults with hematologic malignancies. A Phase 1b extension will occur after dose escalation, enrolling at the RP2D for the T-allo10 cells determined in the Phase 1

leukemia
cell transplantation
  • 0 views
  • 26 Jul, 2021
  • 1 location
Cooking Education and Adapted Physical Activity in Allografted Patients

Majority of patients after allo stem cell transplantation have malnutrition and decrease of physical activities. This state impacts on quality of life and on outcome of some complications like infections, graft versus host disease and could decrease the overall survival. In this study, the investigators propose cooking education and adapted …

  • 0 views
  • 23 Jul, 2021
  • 1 location
Protocol For Genomically Profiling Collecting Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

This research study is a genomic profiling and repository study for children and young adults who have leukemia, myelodysplastic syndrome (MDS) or myeloproliferative syndrome (MPS). Genes are the part of cells that contain the instructions which tell cells how to make the right proteins to grow and work. Genes are …

chronic leukemia
hematologic malignancy
leukemia
acute leukemia
  • 0 views
  • 26 Jul, 2021
  • 2 locations
Is There an Association Between Innate CD8+ T Cells and the Evolution of Tyrosine Kinase Inhibitor Resistance Mutations in Phi+ Hematological Malignancies.

The aim of this project is to test whether low levels of BcrAbl1, despite the presence of resistance mutations, are related to high levels of innate CD8+ T cells, in the hypothesis that these cells have an anti-tumor role. This research aims to investigate: An association between the rate of …

philadelphia chromosome
chronic myeloid leukemia
myeloid leukemia
kinase inhibitor
flow cytometry
  • 0 views
  • 30 Jul, 2021
  • 1 location
A Non-Interventional National Study in Pediatric Patients With Unexplained Enlarged Spleen

(e.g. portal hypertension, haematological malignancy, hemolytic anemia, infection) based on clinical examination and routine biological tests (full blood count, reticulocytes, liver tests, abdominal

  • 0 views
  • 29 Jul, 2021
  • 1 location