Huntington's Disease Clinical Trials

A listing of Huntington's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 18 clinical trials
Study Evaluating Abemaciclib + Aromatase Inhibitors in HR+ HER2- Advanced Breast Cancer Patients (HERMIONE-7)

The HERMIONE-7 trial is a phase II, single-arm, open-label, multicenter study in HR+, HER2- advanced breast cancer patients who have received HD-FUL as first-line endocrine treatment for their

progesterone receptor
measurable disease
abemaciclib
progesterone
metastasis
  • 0 views
  • 19 Jul, 2021
  • 49 locations
Investigating the Efficacy Safety and PK of Roxadustat (FG-4592) for Treatment of Anemia in Pediatric Patients With CKD

end-stage renal disease (ESRD) who are receiving either hemodialysis (HD) or peritoneal dialysis (PD). The study will enroll patients between the ages of 2 to <18 years in two sequential cohorts

  • 0 views
  • 24 Jul, 2021
  • 4 locations
PRidopidine's Outcome On Function in Huntington Disease PROOF- HD

This study will evaluate the efficacy and safety of pridopidine 45mg twice daily (BID) in patients with early stage manifest Huntington Disease (HD).

pridopidine
  • 0 views
  • 22 Jul, 2021
  • 49 locations
A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Dyskinesia in Cerebral Palsy in Children and Adolescents

hyperkinetic movement disorders, namely chorea in Huntington's disease (HD) and tardive dyskinesia (TD). Currently, there is no approved treatment available for Dyskinesia in cerebral palsy (DCP). The

  • 180 views
  • 28 Jul, 2021
  • 79 locations
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

This phase III trial studies response-based chemotherapy in treating newly diagnosed acute myeloid leukemia or myelodysplastic syndrome in younger patients with Down syndrome. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by …

blast cells
cancer
transient myeloproliferative disorder
cytopenia
daunorubicin
  • 153 views
  • 28 Jul, 2021
  • 142 locations
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL Mixed Phenotype Acute Leukemia and B-LLy

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab …

chemotherapy regimen
cancer
cns leukemia
cytarabine
flow cytometry
  • 42 views
  • 28 Jul, 2021
  • 114 locations
Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington Disease

This is the first study of AMT-130 in patients with early manifest HD and is designed to establish safety and proof-of-concept (PoC). CT-AMT-130-01 is a Phase I/II, randomized, multicenter, dose

htt gene
chorea
  • 150 views
  • 28 Jul, 2021
  • 11 locations
iMagemHTT: FIH Evaluation of Novel Mutant Huntingtin PET Radioligands [ C]CHDI-00485180-R and [ C]CHDI-00485626

subsequently in young HCs and Huntington's disease gene-expansion carriers (HDGECs) with Stage II HD (Phase 1b). Subsequent phases will continue to explore the radioligands' binding characteristics in HDGECs

  • 0 views
  • 28 Jul, 2021
Study of Apixaban in Patients Receiving Hemodiafiltration

Atrial fibrillation (AF) is a prevalent and serious disease in hemodialysis (HD) patients. Untreated AF increases the risk of deaths related to cardiovascular events and multiplies the risk of

anticoagulants
anticoagulation therapy
fibrillation
dabigatran
stroke
  • 0 views
  • 19 Jul, 2021
  • 1 location
Safety and Pharmacokinetics of MK-2060 in Older Participants With End-Stage Renal Disease on Hemodialysis (MK-2060-004)

in older adult participants with end-stage renal disease (ESRD) on hemodialysis (HD).

dialysis
nephropathy
body mass index
arteriovenous graft
renal failure
  • 65 views
  • 19 Jul, 2021
  • 3 locations