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Urticaria Clinical Trials

A listing of Urticaria medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (19) clinical trials

Molecular Mechanisms and Diagnosis of Mastocytosis

Mastocytosis is a disorder characterized by presence of excessive numbers of mast cells in skin, bone marrow and internal organs. It can affect both children and adults, males and females and individuals from all ethnic backgrounds, although precise demographic information about the affected populations is not available as it is ...

Phase N/A

The Efficacy and Safety of Desloratadine With Levocetirizine in Treatment of Chronic Idiopathic Urticaria

Objective: To compare the efficacy of desloratadine 5mg (Denosin®) and levocetirizine 5mg (Xyzal®) once daily in the treatment of patients with CIU over 6 weeks. Trial design: Randomized, Double-Blind, Active-Controlled, Parallel-Group Study. Primary endpoint: To evaluate the change in average AM/PM reflective pruritus score from baseline recorded in the subjects’ ...

Phase

Dietary Treatment for Chronic Urticaria

A double blinded parallel randomized control study over 4 weeks will be conducted to assess the effectiveness of a histamine-restricted diet. Neither the subjects nor the medical investigator will know which diet is being prescribed. The study will only be conducted after ethical approval has been granted and with informed ...

Phase N/A

Cold Contact Urticaria Treatment With Rilonacept

Cold contact urticaria (CCU) is a frequent form of physical urticaria that is characterized by the development of wheal and flare type skin reactions due to the release of histamine and other proinflammatory mast cell mediators following exposure of the skin to cold. Typically, symptoms occur within minutes after cold ...

Phase

Kineret CAPS Post Authorisation Study

A non-interventional, post authorization safety study to evaluate the safety of Kineret in the treatment of Cryopyrin Associated Periodic Syndromes (CAPS) in routine clinical care with regard to serious infections, malignancies, injection site reactions, allergic reactions and medication errors, including re-use of syringe.

Phase N/A

Study to Investigate Safety Tolerability Pharmacodynamics and Pharmacokinetics of GSK2646264

This First Time in Human (FTIH) study, which will be performed in three parts, is designed to investigate the safety, local tolerability, pharmacokinetics and pharmacodynamics after single and repeat topical applications of up to 2 strengths of GSK2646264 and corresponding placebo within the same subject, in healthy adult subjects (Part ...

Phase

AWARE - Chronic Urticaria

Non interventional study collecting patient reported outcomes. The study aims to assess the disease burden of chronic urticaria patients and to record the therapies used in daily clinical practice in the UK and the impact they have on the quality of life and work productivity of individual patients.

Phase N/A

Mast Cell Connect: A Registry for Patients With Mastocytosis

Mastocytosis is an extremely rare and heterogeneous spectrum of diseases characterized by the buildup of genetically altered mast cells. Patients experience a wide range of symptoms and in some cases, mast cell buildup can lead to organ dysfunction and failure. Current treatments address disease symptoms and not the underlying cause. ...

Phase N/A

A Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of AK002

This is a Phase 1 study to investigate the safety and tolerability of AK002 in patients with indolent systemic mastocytosis (ISM).

Phase

Screening Protocol for Genetic Diseases of Allergic Inflammation

This protocol is designed to screen subjects (and some family members) with suspected or identified genetic diseases of allergic inflammation or mast cell homeostasis and activation. Patients determined by clinical history and initial outside evaluation by their referring physician to be of interest will be consented and enrolled into this ...

Phase N/A