Bone Diseases Clinical Trials

A listing of Bone Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 36 clinical trials
None
MBCP Safety and Performance in the Osteonecrosis of Femur Head

The aim of this pilot study is to evaluate MBCP performance in bone regeneration after osteonecrosis biopsy of the femur head. This technic may prevent the neck of the femur bone weakness following the healthy area drilling, thanks to a bone reconstruction at the expense of the biomaterial.

arco
  • 1 views
  • 07 Nov, 2020
  • 1 location
None
Osteonecrosis of the Hip and Bisphosphonate Treatment

Osteonecrosis of the hip is an important cause of musculoskeletal disability and finding therapeutic solutions has proven to be challenging. Osteonecrosis means death of bone which can occur from the loss of the blood supply or some other means. Although any age group may develop osteonecrosis, most patients are between …

zoledronic acid
core decompression
arco
hypertension
steroid treatment
  • 17 views
  • 07 Nov, 2020
  • 5 locations
None
Osteosarcoma Maintenance Therapy With OST31-164

Up to 45 Patients aged 12 to 39 with osteosarcoma (bone cancer) that had recurred in the lungs and has recently been surgically removed will be enrolled. Patients will receive OST31-164 infusions every 3 weeks over 48 weeks and be followed after that for 3 years.

  • 0 views
  • 22 Oct, 2021
  • 1 location
None
KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion

The purpose of this study is to evaluate the safety and efficacy of KUR-113 Bone Graft (TGplPTH1-34 in fibrin) compared to local autograft for the treatment of Degenerative Disk Disease (DDD).

spondylolisthesis
autograft
osteophyte
bed rest
scarring
  • 0 views
  • 15 Jul, 2021
  • 14 locations
None
A Study Extension Period of PEG-somatropin (Pegylated-somatropin) in the Treatment of Children With Idiopathic Short Stature

After the first stage (52 weeks) of Phase II clinical trial, Pegylated recombinant human growth hormone (PEG-rhGH) injection of appropriate dose in compliance with ISS clinical treatment strategy is used to treat children with ISS (Idiopathic Short Stature). The long-term efficacy and safety of the investigational product are evaluated, which …

somatotropin
growth hormone
igf-i
somatropin
  • 36 views
  • 21 Jan, 2021
  • 2 locations
None
A Study to Assess the Safety Tolerability and Efficacy of IONIS-GHR-LRx Administered in Patients With Acromegaly

The purpose of this study is to determine the safety, tolerability, and efficacy of IONIS-GHR-LRx subcutaneous (SC) injection as monotherapy in patients with acromegaly.

pegvisomant
ionis-ghr-lrx
bromocriptine
pituitary
insulin-like growth factor
  • 0 views
  • 14 Oct, 2021
  • 22 locations
None
Jaktinib Hydrochloride Tablets In The Treatment of Active Ankylosing Spondylitis

This trial uses a multi-center, randomized, double-blind, placebo, parallel-controlled design, and it is expected that about 105 cases will be enrolled in about 10 sites.

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Multicohort Trial of Trabectedin and Low-dose Radiation Therapy in Advanced/Metastatic Sarcomas

Phase II, multicohort, single arm, open-label, multicenter, international clinical trial with three cohorts (cohort A: Soft tissue sarcoma, cohort B: Bone tumors (osteosarcoma, chondrosarcoma and cohort C: Small round-cell sarcomas (Ewing's sarcoma, rhabdomyosarcoma, desmoplastic small round-cell tumors and other small round cell sarcomas)) with 7 sites in Spain. Main objective: …

systemic therapy
neutrophil count
trabectedin
ewing's sarcoma
soft tissue sarcoma
  • 0 views
  • 29 Nov, 2021
  • 7 locations
None
The Role of 5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Cancers: a Pilot Trial

This study allows head and neck cancer surgeons to specifically visualize cancerous cells apart from normal healthy tissue. 5-aminolevulinic acid (5-ALA) is a safe and effective FDA-approved agent successfully used by neurosurgeons for FGS of different brain tumors is given to the patients preoperatively. Using specific wavelengths of light as …

primary cancer
neutrophil count
  • 0 views
  • 10 Nov, 2021
  • 3 locations
None
Vosoritide for Selected Genetic Causes of Short Stature

Short stature can be caused by a number of genetic etiologies, many of which directly affect the growth plate. The FGFR3/CNP pathway is central to growth of the chondrocyte. The study team hypothesizes that patients with selected genetic causes of short stature that interact with this pathway will benefit from …

regulatory region
hormone deficiency
shox deficiency
KRAS
somatotropin
  • 8 views
  • 10 May, 2021
  • 1 location