Bone Diseases Clinical Trials

A listing of Bone Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 37 clinical trials
Osteosarcoma Maintenance Therapy With OST31-164 (OST-164-01)

Up to 45 Patients aged 12 to 39 with osteosarcoma (bone cancer) that had recurred in the lungs and has recently been surgically removed will be enrolled. Patients will receive OST31-164 infusions every 3 weeks over 48 weeks and be followed after that for 3 years.

  • 5 views
  • 06 Apr, 2022
  • 3 locations
Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis

This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.

debridement
diabetes
diabetic foot
  • 0 views
  • 24 May, 2022
  • 1 location
A Study Extension Period of PEG-somatropin (Pegylated-somatropin) in the Treatment of Children With Idiopathic Short Stature

After the first stage (52 weeks) of Phase II clinical trial, Pegylated recombinant human growth hormone (PEG-rhGH) injection of appropriate dose in compliance with ISS clinical treatment strategy is used to treat children with ISS (Idiopathic Short Stature). The long-term efficacy and safety of the investigational product are evaluated, which …

somatotropin
igf-i
growth hormone
somatropin
  • 42 views
  • 25 Feb, 2022
  • 6 locations
Vosoritide for Selected Genetic Causes of Short Stature

Short stature can be caused by a number of genetic etiologies, many of which directly affect the growth plate. The FGFR3/CNP pathway is central to growth of the chondrocyte. The study team hypothesizes that patients with selected genetic causes of short stature that interact with this pathway will benefit from …

igf-i
malnutrition
cardiofaciocutaneous syndrome
stimulation test
testicular
  • 62 views
  • 10 May, 2021
  • 1 location
ABY-035 in the Treatment of Subjects With Ankylosing Spondylitis

ABY-035-204 is a clinical study to assess the efficacy of IL-17 blocker ABY-035 in ankylosing spondylitis(AS). The primary objective is to estimate the relationship between different dose regimens of ABY-035 and clinical response as assessed by Assessment of Spondyloarthritis International Society 40 (ASAS40) response at Week 16 in subjects with …

x-rays
NSAID
  • 0 views
  • 05 Apr, 2022
The Role of 5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Cancers: a Pilot Trial

This study allows head and neck cancer surgeons to specifically visualize cancerous cells apart from normal healthy tissue. 5-aminolevulinic acid (5-ALA) is a safe and effective FDA-approved agent successfully used by neurosurgeons for FGS of different brain tumors is given to the patients preoperatively. Using specific wavelengths of light as …

primary cancer
neutrophil count
  • 0 views
  • 10 Nov, 2021
  • 3 locations
Multicohort Trial of Trabectedin and Low-dose Radiation Therapy in Advanced/Metastatic Sarcomas

Phase II, multicohort, single arm, open-label, multicenter, international clinical trial with three cohorts (cohort A: Soft tissue sarcoma, cohort B: Bone tumors (osteosarcoma, chondrosarcoma and cohort C: Small round-cell sarcomas (Ewing's sarcoma, rhabdomyosarcoma, desmoplastic small round-cell tumors and other small round cell sarcomas)) with 7 sites in Spain. Main objective: …

metastasis
ewing's sarcoma
soft tissue sarcoma
desmoplastic
anthracyclines
  • 0 views
  • 13 Dec, 2021
  • 11 locations
A Study of CC-99677 in Participants With Active Ankylosing Spondylitis (AS SpA axSpA)

This study is designed to learn about response to CC-99677 treatment by measuring signs and symptoms of Ankylosing Spondylitis (AS), objective measures of disease activity, quality of life assessments, pharmacokinetics, safety, and tolerability over a 12-week double-blind period.

tumour necrosis
back pain
tumor necrosis factor
  • 0 views
  • 22 Mar, 2022
  • 34 locations
Jaktinib Hydrochloride Tablets In The Treatment of Active Ankylosing Spondylitis

This trial uses a multi-center, randomized, double-blind, placebo, parallel-controlled design, and it is expected that about 105 cases will be enrolled in about 10 sites.

  • 4 views
  • 26 Jan, 2021
  • 1 location
Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis Imperfecta

The primary objective of the study is to evaluate bone mineral density (BMD) after 12 months of retreatment with monthly setrusumab in adults with osteogenesis imperfecta (OI).

  • 0 views
  • 15 May, 2022
  • 1 location