Bone Diseases Clinical Trials

A listing of Bone Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 35 clinical trials
Examination How the Administration Period of Teriparatide Affects Bone Metabolism and Bone Mineral Density Prior to Denosumab Therapy

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in osteoporosis patients: The administration period of teriparatide is less than 6 months and thereafter, denosumab for 24 months. The administration period of teriparatide is from 6 to 12 months and thereafter, …

osteoporosis
bone mineral density
denosumab therapy
teriparatide
denosumab
  • 130 views
  • 15 Feb, 2022
  • 1 location
Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents

The primary aim of this proposal is to determine the effects of soluble corn fiber (SCF) supplementation for 1 year on bone metabolism in growing adolescents compared to controls. For the proposed study, a randomized double-blinded placebo controlled clinical trial will be conducted in 236 healthy adolescents aged 10-13 years, …

bone mineral density
calcium
body mass index
Accepts healthy volunteers
  • 34 views
  • 30 May, 2022
  • 1 location
Examination of Efficacy and Safety of Other Anti-Resorption Drugs After 2-year-Denosumab Therapy in Japanese Osteoporosis Patients

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in Japanese osteoporosis patients after 2-year-denosumab therapy: SERM and eldecalcitol treatment for 24 months Bisphosphonates and eldecalcitol treatment for 24 months Eldecalcitol treatment for 24 months

denosumab therapy
osteoporosis
bisphosphonate
denosumab
  • 13 views
  • 01 Feb, 2022
  • 1 location
Theophylline Treatment for Pseudohypoparathyroidism

Pseudohypoparathyroidism is a genetic disorder with limited treatment options. Patients have early-onset obesity, short stature and increased risk of type 2 diabetes. This phase 2 clinical trial will test the efficacy of theophylline, a phosphodiesterase inhibitor, in pseudohypoparathyroidism. The investigators hypothesize that theophylline will cause weight loss, improve glucose tolerance …

diabetes
  • 51 views
  • 04 Mar, 2022
  • 1 location
Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old

Pseudohypoparathyroidism is a genetic disorder with limited treatment options, characterized by early-onset obesity, short stature and resistance to multiple hormones. This phase 2 clinical trial and open-label extension study will test the efficacy of theophylline, a phosphodiesterase inhibitor, in pseudohypoparathyroidism. We hypothesize that theophylline will cause weight loss, slow the …

  • 0 views
  • 07 Oct, 2021
  • 1 location
TXA in Spinal Fusion

Tranexamic acid and placebo will be given during surgery to patients who have elected to undergo lumber interbody fusion on 2 or more levels. Information regarding blood loss, transfusions needed, and duration of hospital stay will be collected.

conservative management
body mass index
spinal fusion
  • 0 views
  • 07 Apr, 2022
  • 1 location
Osteosarcoma Maintenance Therapy With OST31-164 (OST-164-01)

Up to 45 Patients aged 12 to 39 with osteosarcoma (bone cancer) that had recurred in the lungs and has recently been surgically removed will be enrolled. Patients will receive OST31-164 infusions every 3 weeks over 48 weeks and be followed after that for 3 years.

  • 5 views
  • 08 Jul, 2022
  • 4 locations
KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion (STRUCTURE)

The purpose of this study is to evaluate the safety and efficacy of KUR-113 Bone Graft (TGplPTH1-34 in fibrin) compared to local autograft for the treatment of Degenerative Disk Disease (DDD).

osteophyte
spondylolisthesis
conservative management
bed rest
autograft
  • 0 views
  • 20 Apr, 2022
  • 14 locations
Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis

This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.

diabetes
diabetic foot
debridement
  • 0 views
  • 09 Aug, 2022
  • 3 locations
The Role of 5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Cancers: a Pilot Trial

This study allows head and neck cancer surgeons to specifically visualize cancerous cells apart from normal healthy tissue. 5-aminolevulinic acid (5-ALA) is a safe and effective FDA-approved agent successfully used by neurosurgeons for FGS of different brain tumors is given to the patients preoperatively. Using specific wavelengths of light as …

neutrophil count
primary cancer
  • 0 views
  • 10 Nov, 2021
  • 3 locations