Tic Disorders Clinical Trials

We are conducting a treatment study to examine the use of Comprehensive Behavior Intervention for Tics (CBIT). CBIT is the current gold standard first-line behavioral treatment for children and adolescents with tic disorders.  The treatment includes three main components: (1) it helps patients become more aware of their tics, (2) ...

Dr. Kevin Black is conducting a study that looks at children between the ages of 5 and 10 who are experiencing a recent onset of tics. Tics are repetitive, involuntary sounds or movements like eye blinking, sniffing, abdominal tensing or making small noises. The purpose of this research is to ...

Pediatric Subjects are asked to participate in a research study to evaluate the effectiveness, safety, and tolerability of an investigational study drug for the treatment of Tourette Syndrome.  This research study is being conducted by Montefiore Medical Center.

This is a study to evaluate the efficacy and safety of deutetrabenazine (TEV-50717) tablets for the reduction of motor and phonic tics associated with TS in children and adolescents 6 through 16 years of age.

This is an open-label Phase 3 study with a 2-week, double-blind, placebo-controlled, randomized drug withdrawal period to evaluate the safety and efficacy of TEV-50717 tablets in patients who have previously completed participation in Study SD-809-C-17, Study TV50717-CNS-30046, or Study TV50717-CNS-30060.

This is a Phase 2, double-blind, placebo-controlled, randomized withdrawal study to evaluate the safety and maintenance of efficacy of an optimized once-daily (qd) dose of NBI-98854 in pediatric subjects with TS.

The study is a placebo-controlled double-blind randomized study, to determine the benefits of probiotic Lactobacillus plantarum PS128 vs placebo on symptoms for Tic disorders; and the symptoms, behavior, or cognition for Rett syndrome. Patients with the Rett syndrome and Tic disorders/Tourette syndrome will be recruited into our study.The study period ...

Objectives: This study will recruit youth with chronic tics. Chronic tics are the most common movement disorder in children. The goal of the study is to learn how the brain and environment influence children's ability to suppress tics. Specifically, we want to learn how tics are influenced by a certain ...

Gilles da la Tourette syndrome (TS)* is a common chronic neuropsychiatric disorder characterized by motor and vocal tics. In most adult patients, quality of life is significantly impaired. TS, therefore, is a cost-intensive disease (in Germany: mean total costs=3404/year). Despite significant adverse effects, dopamine receptor antagonists were recommended as first ...

This research is being performed to try to understand if the use of deep brain stimulation or DBS can treat the symptoms of Tourette syndrome that do not respond well to current medications. In order to do this the investigators will place small stimulation leads on both sides of the ...