Tic Disorders Clinical Trials

We are conducting a treatment study to examine the use of Comprehensive Behavior Intervention for Tics (CBIT). CBIT is the current gold standard first-line behavioral treatment for children and adolescents with tic disorders.  The treatment includes three main components: (1) it helps patients become more aware of their tics, (2) ...

Dr. Kevin Black is conducting a study that looks at children between the ages of 5 and 10 who are experiencing a recent onset of tics. Tics are repetitive, involuntary sounds or movements like eye blinking, sniffing, abdominal tensing or making small noises. The purpose of this research is to ...

We invite boys and girls aged 6 to 17 who have a diagnosis of Tourette syndrome to see if they may qualify for the T-Force Platinum Research Study. The primary purpose of this research study is to evaluate the safety and effectiveness of an investigational medication, that is not an ...

This is a study to evaluate the efficacy and safety of deutetrabenazine (TEV-50717) tablets for the reduction of motor and phonic tics associated with TS in children and adolescents 6 through 16 years of age.

This is an open-label Phase 3 study with a 2-week, double-blind, placebo-controlled, randomized drug withdrawal period to evaluate the safety and efficacy of TEV-50717 tablets in patients who have previously completed participation in Study SD-809-C-17, Study TV50717-CNS-30046, or Study TV50717-CNS-30060.

This is a Phase 2, double-blind, placebo-controlled, randomized withdrawal study to evaluate the safety and maintenance of efficacy of an optimized once-daily (qd) dose of NBI-98854 in pediatric subjects with TS.

Pediatric Subjects are asked to participate in a research study to evaluate the effectiveness, safety, and tolerability of an investigational study drug for the treatment of Tourette Syndrome.  This research study is being conducted by Montefiore Medical Center.

For many individuals with Tourette syndrome (TS), available medications do not help with their symptoms, or cause significant side effects. Two small controlled trials have investigated the effect of oral delta-9-tetrahydrocannabinol (THC), a principal psychoactive ingredient of cannabis, in TS patients. While these trials have shown promising results, the effect ...

Double-blind randomized, sham-controlled clinical trial of 1 mA bilateral supplementary motor area in adolescents/adults with Tourette syndrome (TS). The primary objectives are to assess and quantify the safety and efficacy on tic severity of 5 inhibitory sessions of active vs. sham tDCS sessions during active tic suppression, and to explore ...

Many individuals with Persistent Tic Disorders (PTDs), including Tourette's Disorder (TD) fail to significantly benefit from existing tic treatments. Case studies have shown morning exposure to light therapy, known to advance circadian phase is associated with modest to large tic reductions (Coles & Strauss, 2013; Niederhofer, 2003) suggesting the presence ...