Tic Disorders Clinical Trials

We are conducting a treatment study to examine the use of Comprehensive Behavior Intervention for Tics (CBIT). CBIT is the current gold standard first-line behavioral treatment for children and adolescents with tic disorders.  The treatment includes three main components: (1) it helps patients become more aware of their tics, (2) ...

Dr. Kevin Black is conducting a study that looks at children between the ages of 5 and 10 who are experiencing a recent onset of tics. Tics are repetitive, involuntary sounds or movements like eye blinking, sniffing, abdominal tensing or making small noises. The purpose of this research is to ...

We are conducting a treatment study to examine the use of Comprehensive Behavior Intervention for Tics (CBIT). CBIT is the current gold standard first-line behavioral treatment for children and adolescents with tic disorders. The treatment includes three main components: (1) it helps patients become more aware of their tics, (2) ...

This is a study to evaluate the efficacy and safety of deutetrabenazine (TEV-50717) tablets for the reduction of motor and phonic tics associated with TS in children and adolescents 6 through 16 years of age.

This is an open-label Phase 3 study with a 2-week, double-blind, placebo-controlled, randomized drug withdrawal period to evaluate the safety and efficacy of TEV-50717 tablets in patients who have previously completed participation in Study SD-809-C-17, Study TV50717-CNS-30046, or Study TV50717-CNS-30060.

This is a Phase 2, double-blind, placebo-controlled, randomized withdrawal study to evaluate the safety and maintenance of efficacy of an optimized once-daily (qd) dose of NBI-98854 in pediatric subjects with TS.

The study is a placebo-controlled double-blind randomized study, to determine the benefits of probiotic Lactobacillus plantarum PS128 vs placebo on symptoms for Tic disorders; and the symptoms, behavior, or cognition for Rett syndrome. Patients with the Rett syndrome and Tic disorders/Tourette syndrome will be recruited into our study.The study period ...

Many individuals with Persistent Tic Disorders (PTDs), including Tourette's Disorder (TD) fail to significantly benefit from existing tic treatments. Case studies have shown morning exposure to light therapy, known to advance circadian phase is associated with modest to large tic reductions (Coles & Strauss, 2013; Niederhofer, 2003) suggesting the presence ...

This is a randomized, controlled trial with two parallel arms. A total of 60 patients will be randomly allocated into the plum-blossom needle group (n=30) and the habit reversal training (HRT) group (n=30). 12-week treatment will be given to all patients of each group, follow-up will be made at the ...

Tourette syndrome (TS) is characterized by the presence of multiple vocal and motor tics. Behavioral disorders associated with TS are common, particularly impulsivity, anti-sociality and socially inappropriate behavior. Specifically, cognitive impulsivity could be the source of these troubles. Its anatomical substrates is based on connections between frontal and striatal areas. ...