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Precocious Puberty Clinical Trials

A listing of Precocious Puberty medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (13) clinical trials

Pharmacokinetic Study of Leuprolide Acetate Injectable Suspension in the Treatment of Central Precocious Puberty

Primary Objectives Determine the effectiveness of leuprolide acetate 45 mg for injectable suspension for treatment of children with CPP. Secondary Objectives - Evaluate the safety and tolerability of leuprolide acetate 45 mg for injectable suspension in children with CPP - Characterize the burst kinetics of leuprolide acetate 45 mg after ...


Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome

Polyostotic fibrous dysplasia (PFD) is a sporadic disorder which affects multiple sites in the skeleton. The bone at these sites is rapidly resorbed and replaced by abnormal fibrous tissue or mechanically abnormal bone. PFD may occur alone or as part of the McCune-Albright Syndrome (MAS), a syndrome originally defined by ...

Phase N/A

Histamine Responsiveness in McCune-Albright Syndrome

Objectives of this study are to determine if: 1. Patients with McCune-Albright syndrome differ from unaffected controls in wheal and flare response to histamine and codeine. 2. Affected skin will differ from unaffected skin in wheal and flare response to histamine and codeine. 3. IgE and IL-4 levels in MAS ...

Phase N/A

Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Children

The goal of CPP-EDG 01 study is to assess possible genetic and/or environmental parameters which may influence the growth rate of children affected by precocious puberty. In this view, we are collecting clinical data and biological samples of children attended as outpatients at the Pediatric Endocrine Center of Pisa from ...


Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders

Overview Our work is divided into two main areas of investigation: the discovery of new, yet-undiscovered genes for conditions of early (i.e. precocious) puberty, delayed puberty, absence of pubertal development (i.e. Kallmann syndrome) as well as normal puberty that is accompanied by an altered reproductive system later in life (i.e. ...

Phase N/A

The Genetic Investigation of Reproductive Disorders (Including Kallmann Syndrome)

The World Health Organization estimates approximately 10% of couples experience some sort of infertility problem. In humans, puberty is the process through which we develop reproductive capacity. Disorders of puberty have provided insight into the biology of reproduction and genetic technologies have enabled us to deepen understanding in this field. ...

Phase N/A

Clinical Trial of Experienced Chinese Herbal Formulas on Different Types of Precocious Puberty

In the research, 138 precocious puberty children are randomly divided into the Ziyinxiehuo granules group (69 cases) and Zishenqinggan granules group(69 cases). Patients in Ziyinxiehuo granules group are treated with a series of experienced chinese herbal formulas, whereas the Zishenqinggan granules group received with different series of experienced chinese herbal ...

Phase N/A

A Study to Assess the Safety and Efficacy of Leuprorelin in Central Precocious Puberty (CPP) Among Chinese Participants

The drug being evaluated in this study is called leuprorelin. Leuprorelin is used to treat children who have CPP. This study will look at long term safety and efficacy of leuprorelin in the treatment of Chinese participants with CPP. The study will enroll approximately 300 participants. All participants who have ...

Phase N/A

Effect of a GnRH Injection on Ghrelin Concentrations in Girls With Suspected Premature Puberty

Patients with clinically suspected central premature puberty undergo a GnRH stimulation test to have an appropriate diagnosis. 20 such girls will be recruited to this study and a modified GnRH stimulation test will be done. The modification includes prolonged blood sampling time (0, 30, 60, 90, 120, and 150 min ...

Phase N/A

The Effect of Medical Clown on the Pain and Anxiety Perception During LRH Analog Treatment or GH Provocation Test

80 children from the endocrine clinic who are referred for treatment with LRH analog or directed to growth hormone tests, will take part in the study: 1.40 children who are referred to decapeptyl treatment will receive the injection once with a medical clown, and the next time with out the ...

Phase N/A