Idiopathic Thrombocytopenic Purpura (ITP) Clinical Trials

A listing of Idiopathic Thrombocytopenic Purpura (ITP) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 52 clinical trials
A Study to Assess Efficacy and Safety of Eltrombopag in Combination With a Short Course of Dexamethasone in Patients With Newly Diagnosed ITP

The purpose of this study is to compare the ability of eltrombopag in combination with a short course of high-dose dexamethasone to induce sustained response off treatment in patients with newly-diagnosed ITP versus 1-3 cycles of dexamethasone monotherapy. The unmet clinical need and the potential for eltrombopag when added to …

platelet count
dexamethasone
eltrombopag
  • 20 views
  • 02 Jul, 2021
  • 20 locations
The Safety Tolerability Pharmacokinetics and Preliminary Efficacy of HMPL-523 in Immune Thrombocytopenia Patients

This is a randomized, double blinded, placebo-controlled phase Ib clinical trial in adult patients with immune thrombocytopenia. Cross-over treatment will be allowed during the study.

anemia
treatment regimen
splenectomy
thrombocytopenia
  • 7 views
  • 26 Jan, 2021
  • 1 location
The Efficacy and Safety of Huaiqihuang Granule in Children With Chronic Primary Immune Thrombocytopenia

This is a multisite, double-blind, randomized, placebo-controlled, and parallel study designed to evaluate the clinical efficacy and safety of Huaiqihuang granule for treatment to children with chronic primary immune thrombocytopenia (Qi Yin deficiency).

anemia
huaiqihuang
initial diagnosis
aptt
thrombocytopenia
  • 0 views
  • 28 Jan, 2021
  • 1 location
Romiplostim Rituximab and Dexamethasone as Frontline Treatment for Immune Thrombocytopenia

The purpose of this study is to determine the response rate and response duration with the combination of low-dose rituximab, romiplostim and high-dose dexamethasone.

dexamethasone
romiplostim
thrombocytopenia
rituximab
platelet count
  • 0 views
  • 25 Jan, 2021
  • 1 location
Dietary Phytoestrogens as Risk Factors for Systemic Lupus Erythematosus

The study aims at determining if dietary phytoestrogens can be risk factors for Systemic Lupus Erythematosus (SLE). Dietary enquiry and phytoestrogens measurements will be performed in blood and urine of patients with SLE in an active phase of the disease, in patient with other autoimmune diseases and in healthy volunteers. …

lupus
autoimmune disease
  • 41 views
  • 26 Jan, 2021
  • 1 location
Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis

Immune thrombocytopenia (ITP) is an autoimmune disease but, paradoxically, and unlike other autoimmune diseases, antiplatelet antibodies are not used either for the diagnosis of the disease or

leukemia
acute leukemia
thrombocytopenia
immune globulin
monoclonal antibodies
  • 0 views
  • 02 Jun, 2021
  • 1 location
Safety and Efficacy of Fecal Microbiota Transplantation

, dysbiotic bowel syndrome, MRSA enteritis, Pseudomembranous enteritis, idiopathic thrombocytopenic purpura (ITP), and atopy. Despite FMT appears to be relatively safe and efficacious in treating a

colitis
vancomycin
crohn's disease
ulceration
encephalopathy
  • 313 views
  • 24 Jan, 2021
  • 1 location
Eltrombopag Combined With Low-dose Rituximab in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, nonrandomized, multicenter clinical trial aims at comparing the efficacy and safety of combined use of eltrombopag with low-dose rituximab vs. the best available therapyBATin adult immune thrombocytopenia with autoantibodies fail (due to intolerance or resistance) to first-line treatment.

immune tolerance
thrombocytopenia
mycophenolate
immunosuppressant
arthritis
  • 0 views
  • 14 Jun, 2021
  • 1 location
Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

Background Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

anemia
eltrombopag
horse anti-thymocyte globulin
neutrophil count
reticulocyte count
  • 114 views
  • 18 Jul, 2021
  • 1 location
Autoreactivity Threshold Analysis in Lupus and Immune Thrombocytopenia (Checkpoints ITP and SLE)

The aim of this proposal is to test if anti-BAFF antibody can restore a normal threshold of tolerance in patients in two auto-immune diseases along the RITUX-PLUS study in immune thrombocytopenia, and along the Believe study in SLE. This work would help to conclude whether or not the 'double hit' …

baff
immune tolerance
thrombocytopenia
lupus
immune globulin
  • 0 views
  • 30 May, 2021
  • 2 locations