Proteinuria Clinical Trials

A listing of Proteinuria medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 88 clinical trials
The Use of Acthar (ACTH) in Patients With Focal Segmental Glomerulosclerosis (FSGS) Who Have Developed Chronic Kidney Disease Stage V (CKD) or End Stage Renal Disease (ESRD) and Are Undergoing a Renal Transplant

This study will evaluate the use of Acthar in patients to undergo renal transplantation and will measure the rate of FSGS recurrence.

kidney transplant
acthar
  • 35 views
  • 13 Oct, 2022
  • 1 location
Improving Post Discharge Care After Acute Kidney Injury (AFTER AKI)

The purpose of this trial is to test the clinical benefit and feasibility of structured risk based post discharge care for hospital acquired Acute kidney injury survivors.This is a Pragmatic randomized controlled trial. It will be conducted at 2 hospitals in Alberta. 166 participants will be enrolled in this Randomized …

dialysis
renal injury
  • 25 views
  • 04 Oct, 2022
  • 2 locations
A Study of the Safety and Activity of Sparsentan for the Treatment of Incident Patients With Immunoglobulin A Nephropathy (SPARTAN)

To determine the nephroprotective potential of treatment with sparsentan in patients newly-diagnosed with immunoglobulin A nephropathy (IgAN) (ie, incident patients) who have not received prior angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) therapy.

nephropathy
proteinuria
angiotensin
enzyme inhibitor
immunoglobulin a
  • 4 views
  • 03 Jun, 2022
  • 1 location
Rituximab Versus Mycophenolate Mofetil in Children With Steroid-dependent Idiopathic Nephrotic Syndrome.

Anti-CD20 monoclonal antibodies are emerging as the steroid-sparing therapy of choice for nephrotic syndrome.This Randomized Clinical Trial seeks to evaluate whether Rituximab biosimilar maintains drug-free disease remission in patients with steroid-dependent nephrotic syndrome for 12-24 months and verify its superiority vs. mycophenolate mofetil (1,200 mg/m2 orally in 2 daily doses). …

  • 0 views
  • 13 May, 2021
  • 1 location
Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis

Prospective, randomized, parallel-group controlled, open-label, international (Asian) multicenter, comparison of corticosteroids combined with TAC and corticosteroids combined with MMF.

corticosteroids
proteinuria
hematuria
nephritis
tacrolimus
  • 67 views
  • 26 May, 2022
  • 1 location
Daratumumab and Pomalidomide in Previously Treated Patients With AL Amyloidosis (DarPAL)

This study aims at establishing a new powerful combination of daratumumab and pomalidomide as rescue treatment for patients with R/R AL amyloidosis.

bone marrow procedure
daratumumab
alkylating agent
dexamethasone
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Urine CXCL10 Monitoring Trial in Kidney Transplant

This is a Phase II-III multi-center prospective randomized controlled clinical trial of incident adult renal transplant patients. The primary objective of this study is to determine if the early treatment of rejection, as detected by urinary CXCL10, will improve renal allograft outcomes.

kidney transplant
cxcl10
  • 29 views
  • 03 Jun, 2022
  • 7 locations
Metformin as RenoProtector of Progressive Kidney Disease (RenoMet)

A multi-center, practice-oriented, repurposing, double-blinded, placebo-controlled, randomized clinical trial. The RenoMet trial is repurposing an already approved agent (Metformin , Glucophage SR ) in a new indication (renoprotection ) in a new class of patients (chronic kidney disease patients CKD 2, 3A, 3B and including patients with renal transplant for …

nephropathy
proteinuria
glomerular filtration rate
  • 2 views
  • 02 Mar, 2022
  • 9 locations
Lipid Management in Renal Transplant Recipients Using Evolocumab.

Cardiovascular disease is the leading cause of mortality after renal transplantation, accounting for more than 30% of deaths. Elevated lipid levels (hyperlipidemia) are a frequent finding following transplantation and the immunosuppressive medications play a central role in the development or worsening of hyperlipidemia. In the general population, the correlation between …

crestor
simvastatin
cholesterol level
cholesterol measurement
hyperlipidemia
  • 0 views
  • 04 Oct, 2022
  • 1 location
PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

This is a phase III, multicenter, randomized, open label, clinical trial to test that hypothesis that plasmapheresis plus rituximab prior to kidney transplantation can prevent recurrent FSGS in children and adults.

monoclonal antibodies
antibiotics
proteinuria
hepatitis c
cancer
  • 102 views
  • 12 Feb, 2022
  • 14 locations