Proteinuria Clinical Trials

Diabetics are at a higher risk for chronic kidney disease since high blood sugar levels caused by diabetes damage blood vessels in the kidneys. If the blood sugar level remains high over many years, this damage gradually reduces the function of the kidneys. Your kidneys filter wastes and excess fluids ...

The purpose of the study is to evaluate whether or not atrasentan is effective in delaying the worsening of kidney disease by comparing the time to serum creatinine doubling or the onset of end stage renal disease in patients with Type 2 diabetes and kidney disease.

NYU Winthrop Hospital Clinical Trials Center is seeking research participants who are 18 years old or older, who are pregnant and between 28 and 37 weeks gestation and are interested in participating in a clinical trial.  Participants will be asked to provide blood and urine sample(s) to be used to ...

Preeclampsia is a complication of pregnancy. Preeclampsia may occur from 20 weeks’ pregnancy through the delivery and postpartum period.  Preeclampsia does not occur in every pregnant woman. It is thought that preeclampsia occurs in about 3 to 5 out of a total of 100 pregnant women. A higher number of ...

The standard of care is expected to remain unchanged during this run-in period. Patients whose proteinuria level remains >1 g/24-hours within 2 weeks of the end of the run-in period, who continue to have hematuria, and who meet blood pressure and eGFR criteria will be eligible to enroll in the ...

Open-label, 24-week, multicenter, exploratory cohort study of VCS - To assess the efficacy of voclosporin (VCS) in achieving complete or partial remission of proteinuria after 24 weeks of therapy in subjects with focal segmental glomerulosclerosis (FSGS). - To assess the safety and tolerability of VCS over 24 weeks in subjects ...

Phenylephrine administration is associated with reductions in CO and SctO2 compared with ephedrine when used for blood pressure management in women with pre-eclampsia undergoing cesarean delivery under spinal anesthesia.

The investigators welcome anyone (with or without a family history) with unexplained, non syndromic FSGS, nephrotic syndrome, or proteinuria to join the study. Participation involves a saliva (or blood if it is preferable) sample and urine sample (if applicable). There is no cost to participate and the study can be ...

BUMP 1 will randomise 2262 women at higher risk of hypertension in pregnancy into usual care or self-monitoring. BUMP 2 will randomise 512 women with hypertension in pregnancy (including chronic hypertension) into usual care or self-monitoring. Women in BUMP 1 will move into BUMP 2 if they develop hypertension. Women ...

A morbidly obese [Body Mass Index (BMI) 45 kg/m2] pregnant woman is at singular risk for all the complications of pregnancy, most notably preeclampsia (PE). Furthermore a woman who is already chronically hypertensive is likely to develop superimposed PE . Uncontrolled systolic hypertension in pregnancy prompts placental abruption, hemorrhagic stroke, ...