Herpes Simplex Infections Clinical Trials

A listing of Herpes Simplex Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 6 clinical trials
Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

Background -DOCK8 deficiency is a genetic disorder that affects the immune system and can lead to severe recurrent infections and possible death from infections or certain types of cancers, including blood cancers. A stem cell transplant is a life-saving treatment for this condition. In this study we are evaluating the …

  • 1 views
  • 22 Jul, 2021
  • 1 location
HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

This study is a clinical trial to determine the safety of inoculating G207 (an experimental virus therapy) into a recurrent or refractory cerebellar brain tumor. The safety of combining G207 with a single low dose of radiation, designed to enhance virus replication, tumor cell killing, and an anti-tumor immune response, …

mg++
neutrophil count
germ cell tumor
absolute neutrophil count
cancer
  • 18 views
  • 18 Jul, 2021
  • 1 location
OH2 Oncolytic Viral Therapy in Solid Tumors

cancers, head and neck cancers, soft tissue sarcomas). OH2 is an oncolytic virus developed upon genetic modifications of the herpes simplex virus type 2 strain HG52, allowing the virus to

measurable disease
colony stimulating factor
cancer
solid tumour
sarcoma
  • 15 views
  • 28 Jul, 2021
  • 1 location
OH2 Injection in Solid Tumors

is an oncolytic virus developed upon genetic modifications of the herpes simplex virus type 2 strain HG52, allowing the virus to selectively replicate in tumors. Meanwhile, the delivery of the gene

mitomycin
breast cancer
measurable disease
colony stimulating factor
cancer
  • 0 views
  • 31 Jul, 2021
  • 1 location
Study of RP1 Monotherapy and RP1 in Combination With Nivolumab

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.

bladder cancer
BRAF
measurable disease
cancer
solid neoplasm
  • 101 views
  • 24 Jul, 2021
  • 34 locations
The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

Background Infections caused by viruses are common causes of illnesses: the common cold, many ear infections, sore throats, chicken pox, and the flu are caused by different viruses. Usually, these illnesses last only few days or, at most, a few weeks. Some virus infections like influenza are cleared from the …

common cold
warts
colitis
human papillomavirus
adenovirus infection
  • 1033 views
  • 28 Jul, 2021
  • 1 location