Herpes Simplex Infections Clinical Trials

A listing of Herpes Simplex Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 23 clinical trials
A Study to Compare Sitavig (Acyclovir) Buccal Tablet With a Placebo in the Treatment of Herpes Labialis in Participants Whose Immune System Works Normally

mouth and lip and that recurs. Herpes labialis is caused by a virus called the herpes simplex virus (HSV). The infection is spread when a person comes into direct contact with someone else who

  • 0 views
  • 25 Jul, 2022
  • 1 location
A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Vaccine Against HSV-2 in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent HSV-2 Genital Herpes

The purpose of this first-time-in-human (FTiH) study is to evaluate the reactogenicity, safety, immune response, and efficacy of an investigational herpes simplex virus (HSV) vaccine. The study

western blot
genital herpes
Accepts healthy volunteers
  • 0 views
  • 03 May, 2022
  • 1 location
Study of 2LHERP® in Genital Herpes Infections (HEARTH-GEN)

Herpes simplex virus (HSV) infection is very common, as most people will experience herpetic infection during their lifetime. The most common manifestation of HSV infection is sores which may

antiviral therapy
antiviral
herpes simplex
  • 1054 views
  • 08 Jul, 2022
  • 12 locations
OH2 Oncolytic Viral Therapy in Non-Muscle-Invasive Bladder Cancer

> OH2 is an oncolytic virus developed upon genetic modifications of the herpes simplex virus type 2 strain HG52, allowing the virus to selectively replicate in tumors. Meanwhile, the delivery of the

  • 0 views
  • 22 Jul, 2022
  • 1 location
OH2 Oncolytic Viral Therapy in Advanced Bladder Cancer

modifications of the herpes simplex virus type 2 strain HG52, allowing the virus to selectively replicate in tumors. Meanwhile, the delivery of the gene encoding human granulocyte macrophage colony-stimulating

  • 0 views
  • 10 Aug, 2022
  • 1 location
Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

Background -DOCK8 deficiency is a genetic disorder that affects the immune system and can lead to severe recurrent infections and possible death from infections or certain types of cancers, including blood cancers. A stem cell transplant is a life-saving treatment for this condition. In this study we are evaluating the …

Accepts healthy volunteers
  • 16 views
  • 09 Aug, 2022
  • 1 location
Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects (PRIOH-1)

Randomized, open-label, multi-center, comparative trial to assess the efficacy and safety in immunocompromised subjects with acyclovir resistant or acyclovir susceptible mucocutaneous HSV

pritelivir
neutropenia
tingling
HIV Infection
diabetes
  • 16780 views
  • 26 Jul, 2022
  • 37 locations
Randomized, Placebo-controlled, Double-blind Study of 2LHERP® in Orofacial Herpes Infections. (HEARTH-OF)

Herpes simplex virus (HSV) infection is very common, as most people will experience herpetic infection during their lifetime. The most common manifestation of HSV infection is sores which may

antiviral agents
herpes infection
  • 633 views
  • 26 Apr, 2022
  • 13 locations
Should We Use Oral Valacyclovir in Acute Herpetic Gingivostomatitis in Children?

Primary herpetic gingivostomatitis is a frequent problem in pediatrics. Complications of this are dehydration, pain and hospitalisation. The objective of this randomized controlled trial is to assess the clinical efficacy of oral Valacyclovir to decrease the duration of symptoms associated with acute herpes gingivostomatitis in children. This study will involve …

valacyclovir
  • 0 views
  • 14 May, 2022
  • 1 location
OH2 Injection in Solid Tumors

is an oncolytic virus developed upon genetic modifications of the herpes simplex virus type 2 strain HG52, allowing the virus to selectively replicate in tumors. Meanwhile, the delivery of the gene

liver metastasis
breast cancer
mitomycin
solid tumour
targeted therapy
  • 0 views
  • 27 Apr, 2022
  • 1 location