Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 769 clinical trials
Evolution of Metabolic and Immune Dysfunction in In-transit Melanoma

Melanoma in-transit metastases (ITMs) continue to represent a therapeutic dilemma, in that no standard method of treatment has been uniformly adopted. The complexity and heterogeneity of patient

tumor cells
serum pregnancy test
systemic therapy
  • 0 views
  • 16 Mar, 2022
  • 1 location
Predicting Response to Immunotherapy for Melanoma With Gut Microbiome and Metabolomics (PRIMM)

This study will investigate the effects of gut microbiome diversity (richness in terms of many bacterial species in the gut) on responses and side effects of immunotherapy in advanced melanoma

advanced melanoma
cancer
  • 7 views
  • 13 Feb, 2022
  • 5 locations
The Impact of Melanoma and Drug Treatment in the Real World

An observational, non-interventional registry study to collect real-world data from people living with melanoma and its treatment, which will be available to researchers to further the knowledge

  • 7 views
  • 14 Oct, 2021
  • 1 location
Q-SAM (Using QPOP to Predict Treatment for Sarcomas and Melanomas)

This is a multi-cohort proof of concept study involving patients with sarcomas or melanomas. Patient models, both two- and three-dimensional, will be derived from tumour samples. These will then

  • 0 views
  • 18 Oct, 2022
  • 1 location
Peripheral T Cell Determinants of Response and Resistance to Pembrolizumab in Melanoma

This is a non-therapeutic study assessing peripheral T cell determinants of response and resistance to immunotherapy in patients with advanced melanoma.The hypothesis is that systemic T cells traffic into the tumor microenvironment (TME) can predict response and resistance to immunotherapy. These systemic tumor directed T cells can be defined by …

pembrolizumab
measurable disease
cancer
advanced melanoma
metastatic melanoma
  • 0 views
  • 24 Nov, 2021
  • 1 location
Cognitive Function in Patients Treated for Metastatic Melanoma With Immune Checkpoint Inhibitors

Immune checkpoint inhibitors (ICIs) are a group of novel immunotherapies that boost the body's own defense against the cancer by improving the immune system's ability to recognize and destroy cancer cells. While it is relatively well-documented that conventional cancer treatments (e.g., chemotherapy) are associated with cognitive impairment, virtually nothing is …

metastatic melanoma
cancer
Accepts healthy volunteers
  • 0 views
  • 13 Mar, 2022
  • 1 location
Biomarkers for the Activity of Immune Checkpoint Inhibitor Therapy in Patients With Advanced Melanoma

follow-up. Collection of blood samples will be aligned with the visits necessary for the administration of the ICI therapy. Collection of archival melanoma metastasis tissues will be performed

advanced melanoma
metastasis
  • 24 views
  • 27 Jan, 2021
  • 2 locations
GI Complications in Cancer Immunotherapy Patients

The purpose of this study is to establish a prospective observational cohort of cancer immunotherapy patients with GI side effects in order to identify biomarkers that predict GI complications due to treatment.

cancer
  • 9 views
  • 22 Apr, 2022
  • 1 location
A Prospective Observational Study on Targeted Therapy for Unresectable or Metastatic BRAFV600E Mutant Melanoma Patients (TavieSkin)

Background The purpose of this study is to describe the profile of patients with BRAF-mutated melanoma treated with BRAF/MEK inhibitors combination and using the Tavie Skin application

BRAF
metastatic melanoma
combinations
targeted therapy
  • 0 views
  • 19 Jun, 2022
  • 1 location
Adjuvant Dabrafenib and Trametinib Treatment in Patients With Completely Resected High-risk Stage III Melanoma. (LEAD Melanoma)

completely resected high-risk stage III (stage IIIA [lymph node > 1mm], IIIB, IIIC and IIID according to AJCC 8th edition) melanoma in Turkey.

stage iii melanoma
trametinib
dabrafenib
immunomodulators
melanoma skin
  • 0 views
  • 16 Mar, 2022
  • 8 locations