Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 751 clinical trials
A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma

The purpose of this study is to evaluate the effectiveness and safety of the combination of Pembrolizumab (KEYTRUDA®) and the investigational drug, Metformin.

measurable disease
pembrolizumab
aptt
hba1c
brain metastases
  • 0 views
  • 22 Mar, 2022
  • 1 location
Nab-PCE vs PC for MM After Failure of Anti-PD-1

This is a randomized controlled clinical trial of nab-paclitaxel + carboplatin Endostatin for advanced melanoma after failure of PD-1 therapy. The aim was to evaluate the efficacy

measurable disease
brain metastases
metastasis
renal function
  • 0 views
  • 03 Feb, 2022
  • 1 location
Postoperative Adjuvant Treatment of Completely Resected Mucosal Melanoma Phase II Study

A mucosal melanoma postoperative adjuvant treatment of multicenter, randomized, double-blind, placebo-controlled phase II study, evaluation of mucosal melanoma patients accept completely

  • 0 views
  • 24 Mar, 2022
  • 1 location
  • 0 views
  • 22 Jan, 2021
  • 7 locations
Study of PAC-1 and Entrectinib for Patients With Metastatic Uveal Melanoma

Single arm study with dose escalation Phase Ib cohort followed by a Phase II cohort. PAC-1 (PO) will be given daily on Days 1 through 21 of each cycle (28-day cycle). Entrectinib (PO) will be given daily on Days 1 through 28 of each cycle. Response will be evaluated after …

  • 0 views
  • 25 Mar, 2022
  • 1 location
Early Integration of Supportive Care for Metastatic Uveal Melanoma Patients (EarlyTogether)

of care in patients with metastatic UM. Supportive care in patients with metastatic Uveal Melanoma (UM)

  • 0 views
  • 02 Feb, 2021
  • 2 locations
Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma

Tumor Treating Fields targeted to liver metastases may improve outcomes for patients with metastatic uveal melanoma treated with immune checkpoint inhibitors.

  • 0 views
  • 22 Apr, 2022
  • 1 location
A Study of Concurrent Stereotactic Body Radiotherapy With Ipi and Nivo in Metastatic Uveal Melanoma

This is a phase 2 trial of concurrent stereotactic radiation therapy (SBRT) with immunotherapy with ipilimumab and nivolumab for up to two years. SBRT will be given in three doses of 15Gy each to 1-5 separate metastases. Ipilimumab will be given at 1mg/kg q 6 weeks for 12 doses, and …

  • 0 views
  • 29 Oct, 2021
  • 1 location
Neoadjuvant SHR-1210 Plus Apatinib for Resectable Stage III-IV Acral Melanoma

Acral melanoma is a melanoma that affects acral areas of the skin, which is the most prevalent site of melanoma in non-Caucasians.Data in this subgroup is scarce.This study is to evalueate the

  • 0 views
  • 03 Jun, 2021
  • 1 location
Stereotactic Body Radiation Therapy and Aflibercept in Treating Patients With Uveal Melanoma

This phase II trial studies how well stereotactic body radiation therapy and aflibercept work in treating patients with uveal melanoma. Stereotactic body radiation therapy is a specialized

  • 0 views
  • 22 Aug, 2021
  • 1 location