Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 751 clinical trials
Nivolumab Plus Relatlimab in Patients With Metastatic Uveal Melanoma

The purpose of this research is to test if a combination treatment of nivolumab and relatlimab will result in tumor reduction in patients with metastatic uveal melanoma.

  • 09 Jan, 2022
  • 2 locations
Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma

This research study is investigating Binimetinib and Belinostat in participants with metastatic uveal melanoma. The research study will test the study drugs to see if the combination of

  • 07 Mar, 2022
  • 1 location
FHD-286 in Subjects With Metastatic Uveal Melanoma

activity of FHD-286 oral monotherapy in subjects with metastatic Uveal Melanoma (UM).

  • 14 Mar, 2022
  • 9 locations
FLX475 in Combination With Ipilimumab in Advanced Melanoma

This clinical trial is a Phase 2, open-label study to determine the anti-tumor activity of FLX475 in combination with ipilimumab in subjects with advanced melanoma previously treated with an

  • 22 Sep, 2021
  • 4 locations
Neoadjuvant/Adjuvant Trial of Darovasertib in Ocular Melanoma (NADOM)

The purpose of this study is to determine the feasibility and tolerability of neo-adjuvant/adjuvant Darovasertib on uveal melanoma patients. Who is it for? Patients may be eligible to

  • 10 May, 2022
  • 1 location
ECT-Pembrolizumab in Patients With Unresectable Melanoma With Superficial or Superficial and Visceral Metastases

This is a Phase 2 multicenter, open label, non-randomized, interventional study enrolling 53 patients.The objectives and purposes of the clinical study described herein are to determine if concomitant Pembrolizumab (Keytruda) and ECT treatments are safe and able to improve local and systemic response rates.ECT will be performed with the CLINIPORATOR …

ct scan
melanoma stage
advanced melanoma
measurable disease
  • 27 Feb, 2022
  • 1 location
ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells (MASE-T) to Patients With Metastatic Melanoma

With the introduction of checkpoint inhibitors substantial improvements have been made in the treatment of malignant melanoma (MM). Despite this still a a subset of patients, approximately 50

neutrophil count
direct bilirubin
metastatic melanoma
cytotoxic t-lymphocyte antigen 4
  • 25 Sep, 2021
  • 1 location
Adjuvant Nivolumab Treatment in Stage II (IIA, IIB, IIC) High-risk Melanoma

. However, to subdivide stage II melanoma patients into having a low or high risk for relapse further methods are needed. This clinical trial will evaluate whether adjuvant nivolumab treatment will

  • 21 Dec, 2021
  • 37 locations
Neoadjuvant Ipilimumab Plus Nivolumab Versus Standard Adjuvant Nivolumab in Macroscopic Stage III Melanoma (NADINA)

primary melanoma patients. Patients will be randomized 1:1 to receive either 2 cycles of neoadjuvant ipilimumab 80 mg + nivolumab 240 mg every 3 weeks followed by a total lymph node dissection (TLND) and

  • 28 Apr, 2022
  • 14 locations
Transarterial Radioembolisation in Comparison to Transarterial Chemoembolisation in Uveal Melanoma Liver Metastasis (SirTac)

Characterisation of effect of SIRT and DSM-TACE as local treatment options for liver metastases in patients with advanced uveal melanoma with respect to progression-free survival and exploratory

liver metastasis
advanced uveal melanoma
measurable disease
  • 23 Feb, 2022
  • 1 location