Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 744 clinical trials
Quality of Life and Psychological Well-being in Patients With Malignant Melanoma

The purpose of this study is to analyse the physical and psychological side-effects in the course of treatment with IFN-alpha. The effectiveness of a specific intervention for the management of these side-effects is evaluated.

  • 12 views
  • 08 Nov, 2020
  • 1 location
Follow-up of Patients With Uveal Melanoma Adapted to the Risk of Relapse (SALOME)

Biomarkers search for early diagnosis of liver metastases in patients with uveal melanoma who benefit from a follow-up tailored to their personalized risk of relapse.

  • 0 views
  • 27 Jan, 2021
  • 1 location
A Study to Evaluate the Safety Pharmacokinetics Pharmacodynamics and Clinical Activity of JNJ-63723283 an Anti-PD-1 Monoclonal Antibody in Participants With Advanced Cancers

participants with selected advanced cancers including non-small-cell lung cancer (NSCLC), melanoma, renal, bladder, small-cell lung cancer (SCLC), gastric/esophageal cancer, and high-level microsatellite

primary cancer
lung cancer
monoclonal antibodies
  • 49 views
  • 15 Sep, 2021
  • 35 locations
Double Immune Checkpoint Inhibitors in PD-L1-positive Stage IV Non-small Lung CancEr

immunotherapy is not clear. Indeed, prolonged responses and long survivals have been described in patients having interrupted the treatment. In the melanoma, a treatment of 6 months of ipilimumab demonstrated

nivolumab
liver metastasis
cancer
pd-l1
tumor cells
  • 22 views
  • 25 Jan, 2021
  • 46 locations
Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)

This study will assess the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of escalating doses of quavonlimab when used in combination with pembrolizumab in participants with advanced solid tumors.

  • 774 views
  • 12 Sep, 2021
  • 56 locations
SentoClone Compared to Reference Treatment in Advanced Malignant Melanoma

The purpose of this study is to elucidate whether SentoClone® gives improved treatment responses in patients with advanced malignant melanoma in comparison to established reference

metastasis
dacarbazine
temozolomide
measurable disease
  • 14 views
  • 08 Nov, 2020
  • 5 locations
Intermittent Selumetinib for Uveal Melanoma

The purpose of this study is to find out what effects, good and/or bad, intermittent dosing of the drug Selumetinib will have on subjects with uveal melanoma. Selumetinib is a drug that blocks

neutrophil count
mek inhibitor
measurable disease
karnofsky performance status
spiral ct scan
  • 0 views
  • 27 Mar, 2021
  • 3 locations
Study of TQB2450 Combined With Anlotinib in Subjects With Advanced Acral Malignant Melanoma

TQB2450 is a humanized monoclonal antibody targeting programmed death ligand-1 (PD-L1), which prevents PD-L1 from binding to PD-1 and B7.1 receptors on T cell surface, restores T cell activity, thus enhancing immune response and has potential to treat various types of tumors.

  • 2 views
  • 23 Jan, 2021
  • 1 location
A Study of Toripalimab or Combining With Temozolomide iv in the Treatment of Advanced/Metastatic Malignant Melanoma

This study evaluate toripalimab or combining with temozolomide for injection in the treatment of advanced/metastatic malignant melanoma. Participants in arm A receive toripalimab, in arm B

braf v600e mutation
systemic therapy
BRAF
temozolomide
  • 0 views
  • 24 May, 2021
  • 1 location
Pembrolizumab in Advanced/Metastatic Acral Lentiginous Melanoma

lentiginous melanoma treated with pembrolizumab

  • 65 views
  • 06 Aug, 2021
  • 1 location