Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 756 clinical trials
Neoadjuvant L19IL2/L19TNF- Pivotal Study (Pivotal)

Phase III, open-label, randomized, controlled multi-center study of the efficacy of L19IL2/L19TNF neoadjuvant intratumoral treatment in Stage III B/C melanoma patients.

neutrophil count
immunologic adjuvant
hepatitis b antigen
cancer
BRAF
  • 123 views
  • 26 Apr, 2022
  • 21 locations
A First-in-Human, Open-label, Phase 1/2 Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Subjects With Advanced Cancers

participants with selected advanced cancers including non-small-cell lung cancer (NSCLC), melanoma, renal, bladder, small-cell lung cancer (SCLC), gastric/esophageal cancer, and high-level microsatellite

monoclonal antibodies
lung cancer
primary cancer
  • 57 views
  • 15 Sep, 2022
  • 16 locations
Monitoring of Immunological Mechanisms and Biomarkers Underlying Efficacy and Toxicity of Cancer Immunotherapy (MINER)

enrolled in the trial: Non-Small Cell Lung Cancer (NSCLC), Head and neck cancer, Melanoma, Bladder cancer, Other tumor types when Immuno-Oncology agent

  • 12 views
  • 26 Apr, 2022
  • 2 locations
Study of Ipilimumab, Nivolumab, and Cabozantinib in Patients With Cutaneous Melanoma

with anti-PD-1/PD-L1 refractory metastatic cutaneous melanoma.

  • 0 views
  • 27 Jun, 2022
  • 1 location
A Study of Toripalimab or Combining With Temozolomide iv in the Treatment of Advanced/Metastatic Malignant Melanoma

This study evaluate toripalimab or combining with temozolomide for injection in the treatment of advanced/metastatic malignant melanoma. Participants in arm A receive toripalimab, in arm B

BRAF
braf v600e mutation
systemic therapy
temozolomide
  • 2 views
  • 24 May, 2021
  • 1 location
ITIL-168 in Advanced Melanoma (DELTA-1)

DELTA-1 is a phase 2 clinical trial to evaluate the efficacy and safety of ITIL-168 in adult subjects with advanced melanoma who have previously been treated with a PD-1 inhibitor. ITIL-168 is a

  • 0 views
  • 14 Jul, 2022
  • 14 locations
Hypofractionated Stereotactic Linear Accelerator Radiotherapy of Uveal Melanoma

target volume (PTV) in patients with uveal melanoma. Patients will be followed-up for 10 years after radiotherapy regarding local tumor control, visual acuity, secondary complications and survival.

conservative treatment
  • 9 views
  • 23 Jan, 2022
  • 1 location
Neoadjuvant/Adjuvant Trial of Darovasertib in Ocular Melanoma (NADOM)

The purpose of this study is to determine the feasibility and tolerability of neo-adjuvant/adjuvant Darovasertib on uveal melanoma patients. Who is it for? Patients may be eligible to

  • 0 views
  • 10 May, 2022
  • 1 location
FLX475 in Combination With Ipilimumab in Advanced Melanoma

This clinical trial is a Phase 2, open-label study to determine the anti-tumor activity of FLX475 in combination with ipilimumab in subjects with advanced melanoma previously treated with an

  • 0 views
  • 28 Jun, 2022
  • 4 locations
Adoptive Tumor-infiltrating Lymphocyte Transfer With Nivolumab for Melanoma

with metastatic melanoma that failed immunotherapy.Tumor-infiltrating lymphocytes will be expanded from resected melanoma samples from the patient and expanded TILs will be transferred to the patient

nivolumab
neutrophil count
platelet count
liver metastasis
hepatitis b antigen
  • 0 views
  • 14 Aug, 2021
  • 1 location