Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 287 clinical trials
UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanoma

UV1 is a therapeutic cancer vaccine that has been explored in prostate, lung cancer, in combination with ipilimumab in malignant melanoma and in combination with pembrolizumab in metastatic

lung cancer
pembrolizumab
neutrophil count
nivolumab
ipilimumab
  • 0 views
  • 04 Oct, 2022
  • 36 locations
A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)

This study will evaluate the efficacy, safety, and pharmacokinetics of treatment combinations in cancer immunotherapy (CIT)-naive participants with resectable Stage III melanoma (Cohort

malignant melanoma of skin
measurable disease
stage iii melanoma
nivolumab
melanoma skin
  • 0 views
  • 20 Oct, 2022
  • 20 locations
A Phase 2, Open-label, Multicenter, Cohort Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy Administered Subcutaneously in Patients With Advanced Cutaneous Melanoma or Intravenously in Patients With Advanced Mucosal Melanoma Who Have Previously Received Anti-PD-[L]-1 Therapy - ARTISTRY-6 (ARTISTRY-6)

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma following prior anti-PD-[L]-1 therapy

malignant melanoma of skin
pembrolizumab
targeted therapy
metastatic melanoma
cytotoxic t-lymphocyte antigen 4
  • 3 views
  • 28 Oct, 2022
  • 28 locations
Molecular Profiling and Matched Targeted Therapy for Patients With Metastatic Melanoma (MatchMel)

This is a patient oriented translational research project aiming to improve clinical outcomes for patients with BRAF and NRAS wild-type unresectable Stage III or Stage IV metastatic melanoma who

NRAS
neutrophil count
targeted therapy
metastatic melanoma
trametinib
  • 0 views
  • 04 Oct, 2022
  • 1 location
Adjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation. (COLUMBUS-AD)

melanoma versus the current standard of care (surveillance).

anticoagulant therapy
BRAF
immunomodulators
neutrophil count
braf v600e mutation
  • 0 views
  • 04 Oct, 2022
  • 17 locations
A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02D

Substudy 02D is part of a larger research study that is testing experimental treatments for melanoma, a type of skin cancer. The larger study is the umbrella study. The goal of substudy

mk-3475
metastasis
pembrolizumab
brain metastases
cancer
  • 0 views
  • 16 Oct, 2022
  • 32 locations
A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02C

Substudy 02C is part of a larger research study that is testing experimental treatments for melanoma, a type of skin cancer. The larger study is the umbrella study. The goal of substudy

mk-3475
alopecia
pembrolizumab
cancer
stage iii melanoma
  • 0 views
  • 24 Oct, 2022
  • 24 locations
A Phase 3, Randomized, Double-blind Study of Encorafenib and Binimetinib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab in Participants With BRAF V600E/K Mutation-Positive Metastatic OR Unresectable Locally Advanced Melanoma

The purpose of this study is to learn about the effects of three study medicines (encorafenib, binimetinib, and pembrolizumab) given together for the treatment of melanoma that

malignant melanoma of skin
pembrolizumab
systemic therapy
measurable disease
advanced melanoma
  • 0 views
  • 20 Oct, 2022
  • 40 locations
A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02B

Substudy 02B is part of a larger research study that is testing experimental treatments for melanoma, a type of skin cancer. The larger study is the umbrella study. The goal of substudy

mk-3475
alopecia
pembrolizumab
cancer
advanced melanoma
  • 6 views
  • 22 Oct, 2022
  • 37 locations
A Multicenter, Open-label Phase 1b Study of the Combination of Binimetinib and Encorafenib in Adolescent Patients With Unresectable or Metastatic BRAF V600-mutant Melanoma

advanced/metastatic melanoma. The study consists of a Safety Run-in Phase to determine the RDE (recommended dose in expansion), followed by an Expansion Phase.

malignant melanoma of skin
metastatic cutaneous melanoma
neutrophil count
melanoma skin
braf v600e mutation
  • 24 views
  • 25 Oct, 2022
  • 6 locations