Hepatitis Clinical Trials

A listing of Hepatitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1364 clinical trials
Development of Non-Invasive MRI Applications for Liver Fibrosis and Inflammation

Chronic liver disease is a major healthcare problem in Hong Kong and worldwide. The diagnosis of liver fibrosis and inflammation in patients with chronic liver disease has important prognostic and therapeutic implications. The current gold standard to evaluate and stage the severity of liver fibrosis and inflammation is based on …

Accepts healthy volunteers
  • 0 views
  • 08 Jun, 2022
  • 1 location
Three-Dimensional T1rho Using Spiral Fast Spin Echo

Liver fibrosis is the main feature in early chronic liver diseases. If identified early, liver fibrosis is reversible. The current gold standard for diagnosing liver fibrosis is invasive liver biopsy. Existing non-invasive methods still have significant limitations. T1rho imaging is a promising non-invasive technology evaluating liver fibrosis. It does not …

liver disease
Accepts healthy volunteers
biopsy of liver
fibrosis
  • 0 views
  • 03 Jun, 2022
  • 1 location
Comparison Between LDCT With DL Recontruction and Standard Dose CT

This prospective study aims to perform intra-individual comparison of the image quality between low dose liver CT with deep learning reconstruction and standard dose liver CT with iterative reconstruction in patients with liver metastasis.

  • 0 views
  • 15 Jun, 2022
  • 1 location
T1rho Imaging of Liver in Presence of Iron

Liver T1rho is elevated in response to accumulation of extracellular matrix proteins during fibrosis. The presence of hepatic iron overload; however, can shorten the T1rho value. With proper correction, we can remove this confounding factor and improve the reliability of T1rho for early diagnosis of liver fibrosis. Patients with early-stage …

iron
Accepts healthy volunteers
fibrosis
  • 0 views
  • 05 Jun, 2022
  • 1 location
Intra-arterial Perfusion in Interventional Radiology

Patients are being asked to participate in a study to better determine blood flow going to tumors in the liver. They will undergo an embolization procedure in interventional radiology where the goal is to provide treatment directly into the liver tumor. These treatments are delivered into the blood vessels feeding …

  • 0 views
  • 22 Jul, 2022
  • 1 location
Multi-Detector CT Angiography With 3D Reconstruction Versus Digital Subtraction Angiography

This study aims to investigate the feasibility and accuracy of Multi-Detector CT angiography acquired before Trans-arterial Chemo-embolization (TACE) in detecting Hepato-cellular carcinoma feeding vessels compared to DSA angiography acquired during TACE.

  • 0 views
  • 28 Jul, 2022
Development of Novel MRI Methods for Detecting, Discriminating, and Measuring Liver Fibrosis and Congestion in Fontan Patients

In this research study, the investigators will conduct a prospective cross-sectional study of pediatric and adult Fontan patients that will correlate a variety of quantitative MRI biomarkers with histopathologic data.

biopsy of liver
fibrosis
  • 7 views
  • 03 Mar, 2022
  • 1 location
Anti-PD-1/PD-L1 Antibodies Plus Pegylated Interferon Alfa-2b Treatment in Patients With Advanced-Stage HCC

This study is being done to analyze the safety, tolerability, and efficacy of treatment using combination of Pegylated Interferon Alfa-2b and anti-PD-1/PD-L1 antibodies for patients with advanced hepatocellular carcinoma.

cancer
measurable disease
pembrolizumab
  • 0 views
  • 24 Apr, 2022
  • 1 location
Prognostic Value of Liver Cancer CTCs Isolated by a Novel Microfluidic Platform

This study aims to isolate CTCs in peripheral venous blood of liver cancer patients by inertial focusing principle-based microfluidic device, determine the relationship between the number of CTCs and patient prognosis and treatment response, detect mutation, copy number variation and mutation load in CTC cells and corresponding tissues using single-cell …

cancer
Accepts healthy volunteers
tumor cells
  • 0 views
  • 26 Mar, 2022
  • 1 location
A Single Center Real-world Study of Donafenib in the Treatment of Hepatocellular Carcinoma in Routine Clinical Practice

This trial is a single center observational real-world study. It is planned to include 300 patients with unresectable hepatocellular carcinoma (uHCC) treated with Donafenib. The purpose of the study was to observe the effectiveness and safety of Donafenib in the real world.

  • 0 views
  • 19 Apr, 2022