Glomerulosclerosis Clinical Trials

In this study Retrophin is studying an investigational drug called Sparsentan for treatment of patients with FSGS. The trial is being conducted to collect information about the possible effects of Sparsentan to treat protein loss in patients with FSGS, as well as other positive and negative effects of the medication.

This study evaluates an investigational oral tablet compared to placebo that may help manage your blood glucose levels.  

This study is to evaluate the safety of an existing diabetes drug and how it may help individuals with kidney disease. 

People with focal segmental glomerulosclerosis are asked to participate in a research study being conducted by New York University School of Medicine.  

People with primary focal segmental glomerulosclerosis are asked to participate in a research study being conducted by Montefiore Medical Center.

Open-label, 24-week, multicenter, exploratory cohort study of VCS - To assess the efficacy of voclosporin (VCS) in achieving complete or partial remission of proteinuria after 24 weeks of therapy in subjects with focal segmental glomerulosclerosis (FSGS). - To assess the safety and tolerability of VCS over 24 weeks in subjects ...

The investigators welcome anyone (with or without a family history) with unexplained, non syndromic FSGS, nephrotic syndrome, or proteinuria to join the study. Participation involves a saliva (or blood if it is preferable) sample and urine sample (if applicable). There is no cost to participate and the study can be ...

1.0 Background 1.1 Definitions of chronic kidney disease The Kidney Disease Outcomes Quality Initiative (K/DOQI) of the National Kidney Foundation (NKF) defines chronic kidney disease as either kidney damage or a decreased glomerular filtration rate (GFR) of less than 60 mL/min/1.73m2 for 3 or more months. Whatever the underlying etiology, ...

Serum, plasma, and fresh urine samples as well as whole blood (buffy coat for DNA extraction and genotyping) are stored at -80C in a local biobank according to the latest guidelines of the Acadmie Suisse des Sciences Mdicales (ASSM). The vascular phenotype includes: 24h ABPM with the examination of diurnal ...

Ayurvedic treatment includes some complex classical herbal formulations and Niruha basti (procto-colonic administration of ayurvedic medicines mainly contained decoction of punarnavadi compound, rocksalt, sesame oil and mixture of some herbal poweders) will be given to the patients of chronic kedney disease who are not on dialysis. Patients of CKD of ...