Idiopathic Short Stature Clinical Trials

A listing of Idiopathic Short Stature medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 9 clinical trials
A PHASE 2 MULTIPLE DOSE, RANDOMIZED STUDY TO ASSESS THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND EFFICACY OF RECIFERCEPT IN CHILDREN WITH ACHONDROPLASIA

Approximately 63 participants will be randomized to one of three doses to receive Recifercept either Low Dose Medium Dose High Dose Participants will will attend the clinic at baseline and at Day 1, 4, 8, 15, 29 & then Month 2, 3 6, 9 & 12. Assessments include safety, blood …

testicular
  • 43 views
  • 23 Oct, 2022
  • 12 locations
Natural History Study of Albright Hereditary Osteodystrophy: Includes Substudies on Effects of Growth Hormone in Patients With Pseudohypoparathyroidism Type 1A and Cognitive & Behavioral Studies in Albright Hereditary Osteodystrophy

hormone in a prior clinical trial (under R01 FD00FD003409, IND 67148, which ended); or those who meet the criteria of idiopathic short stature or SGA. We are also evaluating neurocognitive and

  • 136 views
  • 24 Oct, 2022
  • 1 location
Metabolic Study of Cockayne Syndrome (METABO-CS)

Cockayne syndrome (CS) is related to defective DNA transcription and/or repair and belongs to the family of Nucleotide Excision Repair. It is an autosomal recessive multisystemic disorder characterized by mental retardation, microcephaly, severe growth failure with lipoatrophia, sensorial impairment, cutaneous photosensitivity, dental decay, enophtalmios. The disease is progressive causing severe …

Accepts healthy volunteers
  • 9 views
  • 04 Oct, 2022
  • 1 location
  • 0 views
  • 29 Oct, 2022
  • 1 location
An International, Prospective Registry Investigating the Natural History of Participants With Achondroplasia

This is a registry study in children with achondroplasia, age 0-10 years, to be conducted at multiple clinical centers in several countries. Information collected will include in anthropometric characteristics, related symptoms, tests, & treatments Children's information will be collected in the registry for a maximum of 5 years.

  • 27 views
  • 21 Oct, 2022
  • 20 locations
Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy

Four rare genetic diseases, xeroderma pigmentosum (XP), Cockayne syndrome (CS), the XP/CS complex and trichothiodystrophy (TTD) have defective DNA excision repair although only XP has increased cancer susceptibility. We plan to perform careful clinical examination of selected patients with XP, XP/CS, CS, or TTD and follow their clinical course. We …

Accepts healthy volunteers
cancer prevention
cancer
  • 77 views
  • 24 Oct, 2022
  • 1 location
Genetic Causes of Growth Disorders

Background Some growth disorders are caused by a change in genes. Genes are the instructions the body uses to function. Changes in genes often cause them not to work correctly. Researchers want to use a new technology called exome sequencing, to look at many genes at once. This is done …

x-rays
somatotropin
GH deficiency
short stature
hormone deficiency
  • 72 views
  • 14 Oct, 2022
  • 1 location
Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and Genotype Phenotype Correlation

Background Osteogenesis Imperfecta (OI) is a connective tissue disorder. OI affects many aspects of a person s health and growth. It can cause frequent fractures, short stature, and bowing of the long bones. There is no known cure for OI so researchers want to learn more about it. Objectives To …

probe
computed tomography
x-rays
col1a1
autosomal dominant
  • 38 views
  • 04 Oct, 2022
  • 1 location
The Impact of the Use of Recombinant Human Growth Hormone on ADHD Characteristics in Children and Adolescents

Analysis of the short-and long-term impact of recombinant growth hormone on attention deficit and hyperactivity charachteristics in children and adolescents. This will be examined in children prior to GH therapy and 3, 6 and 12 months during treatment, by filling validated questionnaires (Vanderbilt rating scales) evaluating ADHD. Data will be …

attention deficit hyperactivity disorder
somatotropin
GH deficiency
Accepts healthy volunteers
chronic renal failure
  • 117 views
  • 04 Oct, 2022
  • 1 location