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Follicular Lymphoma Clinical Trials

A listing of Follicular Lymphoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (416) clinical trials

A Phase 1 Multiple Ascending Dose Study of DS-3201b in Japanese Subjects With Lymphomas

This will be a First-in-Human, Phase 1, multi-center, non-randomized, open label study of DS-3201b, Histone-lysine N-methyltransferase EZH1/2 dual inhibitor to assess its safety and tolerability, identify a maximum tolerated dose (MTD)/ tentative recommended phase 2 dose (RP2D), and assess its pharmacokinetic/dynamic properties in Japanese subjects with Non-Hodgkin's Lymphoma.

Phase

Ultra Low Dose 4 Gy Orbital Radiation for Definitive Therapy of Indolent B Cell Lymphoma

Baseline Tests: If you agree to take part in this study, the following baseline tests and procedures will be performed You will have a physical exam. Blood (about 2 teaspoons) will be drawn for routine tests. This routine blood draw will include a pregnancy test if you can become pregnant. ...

Phase

A Clinical Research of CAR T Cells Targeting CD19 Positive Malignant B-cell Derived Leukemia and Lymphoma

Nowadays refractory or relapsed leukemia/lymphoma lacks effective treatment. Innovative therapy is urgently required. Chimeric antigen receptor (CAR)-modified T cells have demonstrated great successes in treating even late stage cluster of differentiation antigen 19 (CD19) positive B cell malignancies. To design better CAR T cells, we have developed new CD19 CARs. ...

Phase

AMH as a Predictor of Infertility Risk in Children With Cancer (CHANCE)

In this clinical trial, we will prospectively evaluate the AMH level before and after treatment (up to 18 years old) in a large cohort of pre- and post-pubertal children treated for cancer. The children enrolled are young patients between 3 and 14 year old who are newly diagnosed with cancer ...

Phase N/A

Rituximab With or Without Yttrium Y-90 Ibritumomab Tiuxetan in Treating Patients With Untreated Follicular Lymphoma

PRIMARY OBJECTIVES: I. Test the hypothesis that a single dose of Zevalin (yttrium Y-90 ibritumomab tiuxetan) rituximab immunotherapy (RIT) will increase the complete remission (CR) rate over that achieved with standard rituximab in patients with untreated asymptomatic follicular lymphoma (FL). SECONDARY OBJECTIVES: I. Test the hypothesis that Zevalin RIT will ...

Phase

A Clinical Research of BCMA-Targeted CAR-T in B Cell Malignancies

B-cell maturation antigen(BCMA) is preferentially expressed in mature B lymphocytes as well as in B-cell derived leukemia, lymphomas, and multiple myeloma. Despite of the fact that CD19-targeted CAR-T can re-induce remissions for many patients with relapsed and refractory B cell malignancies, a part of those patients will relapse with CD19-negative ...

Phase

Social Media Listening in Improving Clinical Trial Recruitment in Patients With Cancer

PRIMARY OBJECTIVES: I. Examine the feasibility (acceptance among University of Southern California [USC] Norris study team members and Twitter users in Los Angeles [LA] county) of targeted social media listening (SML) via Twitter as a tool for enhancing recruitment to cancer trials. II. Gain preliminary data on the impact (i.e., ...

Phase N/A

Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological Cancers

OBJECTIVES Primary To evaluate the effect of prophylactic transfer of donor CD4 cells after T-cell depleted reduced-intensity HLA-identical sibling transplantation upon the risk of relapse or progression in patients with haematological cancers (e.g. NHL, HL, CLL/PLL, PCM, AML, ALL, MDS or CMML depending on the disease status). Secondary To evaluate ...

Phase

Gemcitabine/Clofarabine/Busulfan and Allogeneic Transplantation for Aggressive Lymphomas

Study Drug Administration and Pharmacokinetic (PK) Testing: The days before you receive your stem cells are called minus days, such as Day -2, Day -1. The day you receive the stem cells is called Day 0. The days after you receive the stem cells are called plus days, such as ...

Phase

Allogeneic Stem Cell Transplantationin Relapsed Hematological Malignancy: Early GVHD Prophylaxis

In this study, the investigators will utilize a regimen combining low dose total body irradiation and rabbit ATG to facilitate stem cell transplantation (SCT) with HLA matched related and unrelated donors. Based on the hypothesis that early treatment interventions have significant late effects in allogeneic SCT, a simple intervention, varying ...

Phase