Search Medical Condition
Please enter condition
Please choose location

Sleep Apnea Syndromes Clinical Trials

A listing of Sleep Apnea Syndromes medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (135) clinical trials

The purpose of this study is to obtain additional long-term safety and efficacy data on the use of Inspire therapy.

Phase

The purpose of the study is to evaluate the response to pain medication in participants with both treated and untreated obstructive sleep apnea. This study will last about 3 weeks. There are 2 to 3 study visits. Total participation will take about 5.5 hours. There will be a home sleep ...

Phase N/A

The purpose of this research study is to determine whether Lemborexant, an investigational medication, decreases the peripheral oxygen saturation (amount of oxygen in the blood) during sleep time in adult subjects with mild OSA (AHI ≥5 to <15) after taking Lemborexant compared with a placebo. This study is comprised of ...

Phase

Effect of Positive Airway Pressure Therapy on Hospitalization and Mortality in SDB Patients With Comorbid Chronic Obstructive Pulmonary Disease (COPD) or/and Heart Failure (HF)

In this retrospective analysis the health care utilization in patients with COPD and HF will be quantified. Data of patients who additionally underwent a polysomnography or polygraphy between 2012 and 2015 are taken into consideration. The data (risk for hospitalization and death, comorbidities, diagnosis and therapy of SDB, costs of ...

Phase N/A

Radiofrequency Ablation for Multi-level Obstructive Sleep Apnea: A Single-arm Multicenter Study

The United States is currently experiencing an increase in the incidence and prevalence of obstructive sleep apnea (OSA). With prevalence in middle-aged adults of 2 to 4% of the population, untreated OSA has been implicated in increased risk for cardiovascular disease, including hypertension and heart failure, daytime sleepiness, and increased ...

Phase N/A

CPAP vs ASV for Insomnia

Patients presenting to the sleep clinic with a primary complaint of insomnia will be potential participants for this study. Following diagnostic polysomnography (PSG) testing, insomnia patients diagnosed with SDB and meeting inclusion criteria will be randomized to a PAP treatment arm, CPAP or ASV. Participants will complete titration studies with ...

Phase

Adaptive Servo Ventilation (ASV) in Heart Failure

Sleep disordered breathing (SDB) is common in patients with heart failure (HF) and is an independent predictor of morbidity and mortality. Adaptive servo-ventilation (ASV) is reported as the most effective treatment for SDB in HF and has been shown to improve cardiac function in patients with HF coexistent with SDB. ...

Phase N/A

SORT - AF Supervised Obesity Reduction Trial for AF Ablation Patients

Study protocol: The purpose of this study is to proof a professional care of overweight patients with symptomatic atrial fibrillation, as well as the treatment of the risk factors for atrial fibrillation, especially obstructive sleep apnea and hypertension. There is a 1:1 randomization. In the intervention group, patients are followed ...

Phase N/A

Clinical Trial in Patients With Hypertension and Left Ventricular Dysfunction

The scope of this entire study is to examine the patients as follows:: Complete Echocardiographic Study including the index of left ventricular mass and relative wall thickness (RWT), measurement acquired from left parasternal longitudinal axis. Further assessment will be diastolic function and filling pressures of the left ventricle using all ...

Phase N/A

Validation of the ApneaScan Algorithm in Sleep Disordered Breathing

72 patients with heart failure with reduced ejection fraction (HFREF) who have been selected to receive an Implantable Cardioverter-Defibrillator (ICD) or Cardiac Resynchronization Therapy Pacemaker or Defibrillator (CRT-P/D) will undergo pre-implant assessment with an echocardiogram, B-type Natriuretic Peptide (BNP) level, 6 minute walk test, Minnesota living with heart failure and ...

Phase N/A