Hepatitis B Clinical Trials

A listing of Hepatitis B medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 330 clinical trials
Studying Radiation Doses in Patients Undergoing Stem Cell Transplant Treated With Total-Body Irradiation

RATIONALE: Studying samples of blood and urine from patients with cancer in the laboratory may help doctors learn more about radiation doses and predict how patients will respond to treatment. PURPOSE: This research study is evaluating radiation doses in patients undergoing stem cell transplant treated with total-body irradiation.

  • 07 Nov, 2020
  • 1 location
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA

The research is aimed at identifying new predisposition genes for endocrine tumours. Our focus initially is on pituitary adenomas including growth hormone-secreting tumors (somatotrophinomas) and prolactin secreting tumours (prolactinomas), but we wish to extend work to other pituitary tumour cases/families. The recruitment process will be as follows. We will recruit …

aip gene
growth hormone
  • 22 Jan, 2021
  • 2 locations
Viscoelasticity Imaging to Assess Liver Cancer

Ultrasound (US) used for hepatocellular carcinoma (HCC) surveillance suffers from low sensitivity (60-78%) due to fatty liver, obesity, and diffusely nodular appearance in cirrhosis. Once a suspicious malignant lesion is detected at US, guidelines recommend contrast-enhanced US, magnetic resonance imaging (MRI) or computed tomography (CT) scans to confirm suspicion. The …

  • 29 Jan, 2021
  • 1 location
The New LC-MS/MS Method for Determination of Unbound Tacrolimus in Plasma

Tacrolimus (TAC) is characterized by a narrow therapeutic window, as well as high inter- and intra-individual variability in pharmacokinetics. Both under- and overexposure may lead to severe adverse effects. Therapeutic drug monitoring (TDM) is an essential element of post-transplant patient care. Most transplantation centers use C0 to adjust TAC dosage. …

  • 28 Jan, 2021
  • 1 location
Role of mHealth-based Interventions Including Social Media to Improve Childhood Immunization Coverage During COVID 19 Pandemic in Pakistan: Qualitative Study

In order to improve routine immunization uptake during COVID-19 pandemic, and to understand the perceptions and barriers related to vaccine hesitancy and coverage during COVID 19 and to explore the need for COVID-19 vaccination, separately and as a part of routine immunization, the investigators will be using qualitative methodology to …

  • 22 Sep, 2021
  • 1 location
Bezafibrate in Patients With Primary Biliary Cholangitis (PBC)

Up to 40% of patients with PBC have an inadequate response to standard treatment with UDCA, hence bezafibrate, a PPAR-agonist is being introduced as add-on therapy in these patients. sCD163, fibrosis markers and bile acid composition are of special interest in PBC. In this study, the investigators will investigate how …

  • 26 Jan, 2021
  • 2 locations
Prospective Tissue Collection Research Protocol

This study aims to collect matched donor tissue and blood to enable the development of a manufacturing process for potential immunotherapies.

blood transfusion
breast cancer
lung cancer
  • 02 Sep, 2021
  • 8 locations
sCD163 in PBC Patients - Assessment of Treatment Response

Primary biliary cholangitis (PBC) is an autoimmune chronic liver disease, characterised by destruction of the small intrahepatic bile ducts. Ursodeoxycholic acid (UDCA) is the first line treatment for patients with PBC. However, up to 40% of patients respond inadequate to this treatment. sCD163 is a macrophage activation marker shedded into …

first line treatment
biopsy of liver
  • 07 May, 2021
  • 1 location
Microvesicles and Monocytes to Predict Mortality of Patients With Cirrhosis

Chronic liver diseases related to viral hepatitis, metabolic syndrome or excessive alcohol consumption can evolve towards cirrhosis. Cirrhosis is responsible for 170 000 deaths per year in Europe. Initially asymptomatic and called "compensated" it can become "decompensated" with the developement of acute complications such as infections, ascites or variceal bleeding. …

liver failure
  • 06 Sep, 2021
  • 6 locations
Magnetic Resonance Technics for the Assessment of Liver Function Before and After TIPS

Portal hypertension is the end-stage fatal complications of liver cirrhosis. Decompensated cirrhosis patients can pass through transjugular intrahepatic portosystemic shunt to effectively prevent bleeding and refractory ascites. However, the occurrence of hepatic encephalopathy and liver function failure, infection, bleeding again are main lethality postoperative complications after TIPS. The accurate TIPS …

varicose veins
hepatic venous pressure gradient
biopsy of liver
  • 23 Jan, 2021
  • 1 location