Pleural Diseases Clinical Trials

A listing of Pleural Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 143 clinical trials
Efficacy of Non-instrumental Pleural Chest Physiotherapy (KINEPANCH)

The main purpose of this study is to assess efficacy of non instrumental pleural chest physiotherapy on the recovery of respiratory function, at hospital discharge or 15 days after beginning the

  • 10 views
  • 10 Feb, 2022
  • 13 locations
A Randomized Blinded Controlled Trial of EXPAREL vs 1% Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Catheter Placement

This phase II trial investigates the effect of EXPAREL compared to lidocane as a local anesthetic in patients who are undergoing pleuroscopy with pleural biopsy and indwelling pleural catheter

  • 0 views
  • 16 Oct, 2022
  • 1 location
Pembrolizumab and Hypofractionated Stereotactic Radiotherapy in Patients With Malignant Pleural Mesothelioma

This is a multi-centre non-randomised open-label phase 1 trial of pembrolizumab given in combination with SBRT to part of a pleural-based lesion in patients with unresectable MPM. This study

  • 0 views
  • 18 Apr, 2021
  • 4 locations
IrRigation of the INfected Pleural Space With antiSEptic Solution (RINSE) - a Proof of Concept Study (RINSE)

Pleural antiseptic irrigation (PAI) is used in conjunction with open drainage for treating adults with chronic post-thoracotomy empyema. The antiseptic povidone-iodine can safely be instilled

  • 0 views
  • 19 Oct, 2022
  • 1 location
A Pilot & Feasibility Study of Intraoperative Imaging With OTL38 In Patients With Lung and Pleural Nodules

the study is to determine the sensitivity of OTL uptake and expression in identifying those lung and pleural nodules when excited by an imaging probe. There will be a single dose of 0.025 mg/kg for

  • 2 views
  • 16 Apr, 2019
  • 1 location
Cytoreductive Surgery and Hyperthermic Intrathoracic Chemotherapy for the Treatment of Thymic Epithelial Malignancies With Pleural Spread or Recurrence (CHOICE): a Prospective, Open, Single-arm Study Choice (CHOICE)

Hyperthermic intrathoracic chemotherapy (HITOC) offers an additional treatment option for malignant pleural tumors after surgical cytoreduction. Especially it is used to further improve local

  • 0 views
  • 15 Oct, 2022
  • 1 location
Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction (SAVED-1)

The purpose of this protocol is to perform a pilot prospective controlled clinical trial to evaluate the potential role of lung fissure completion with pleural adhesiolysis strategy

  • 0 views
  • 30 Jun, 2022
  • 1 location
Ultrasound- Guided Retro Superior Costotransverse Ligament (SCTL) Compartment Block

. Although it is a safe technique, the needle tip comes close to the pleura during the injection, therefore, increasing the potential for pleural puncture and pneumothorax, especially when performed by

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Video Assisted Thoracoscopic Decortication Versus Interventional Radiology Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema (DICE Trial) (DICE)

The American Association of Thoracic Surgery defines empyema as pus in the pleural space. It is a common thoracic surgery presentation with an estimated 65,000 cases occurring annually in the

  • 36 views
  • 13 Oct, 2022
  • 1 location
Digital Chest Tube Drainage System (Thopaz+) Versus Analog in Pediatric Patients (THOPAZ)

, objective measurement of air leaks as well as maintaining a constant pleural pressure. The adult literature describes multiple benefits of using a digital drainage system, only two studies to date have

  • 0 views
  • 04 Oct, 2022
  • 1 location