Hematological Disorders Clinical Trials

A listing of Hematological Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 2099 clinical trials
AI Algorithms to Automate the TMI by VMAT Optimization Using WB-CT/MRI and Synthetic WB-CT - The AuToMI Project

Total Body Irradiation (TBI) was shown to help in providing immunosuppression that facilitates the donor transplant acceptance. Randomized trials demonstrated that conditioning regimens to bone marrow transplantation (BMT) including TBI have produced better survival rates than chemo-only regimens. The TBI target is represented by the whole BM, and eventually the …

total body irradiation
cell transplantation
  • 0 views
  • 04 Aug, 2021
  • 1 location
Mind-body Medicine for Patients With Malignant Hematological Diseases

This randomized controlled trial aims to investigate the effectiveness of a mind-body group program as a supprtivemanagement strategy for fatigue in patients with malignant hematological

blood disorder
cancer
remission
  • 9 views
  • 15 May, 2021
  • 2 locations
UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

This is a phase II trial using a non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen with modifications based on factors including diagnosis, disease status, and prior treatment. Single or double unit selected according to current University of Minnesota umbilical cord blood graft selection algorithm.

lymphoid leukemia
blast crisis
blast cells
burkitt's lymphoma
mantle cell lymphoma
  • 42 views
  • 25 Jan, 2021
  • 1 location
  • 2 views
  • 07 Mar, 2021
  • 1 location
Medical Home Care for Hematopoietic Stem Cell Transplantation Phase 2

Hematopoietic stem cell transplantation (HCT) has the potential to cure a variety of malignant and non-malignant diseases. However, it is associated with significant morbidity, and treatment-related mortality. This is due in large part to the prolonged pancytopenia and immunosuppression associated with the preparatory regimen of chemotherapy and/or radiation and the …

graft versus host disease
cancer
cell transplantation
  • 6 views
  • 19 Sep, 2021
  • 1 location
Using DNA-Typing and Erythrocyte Microparticle Analysis to Detect Blood Doping

A total of 12 subjects will be recruited for participation in this study. 6 subjects will receive re-infusion of autologous blood, and 6 subjects (anemic patients) will receive a homologous transfusion.

blood transfusion
  • 75 views
  • 25 Jan, 2021
  • 1 location
Phase I Study of CTL Anti-DP Infusion Post-hematopoietic Stem Cell Transplantation

For several decades, allogeneic hematopoietic stem cell trans-plantation (allo-HSCT) has remained an important strategy in the management of patients with high-risk hematological malignancies. The acceptance of umbilical cord blood (UCBT) and haploidentical grafts (Haplo) as viable alternative donors for allo-HSCT has increased the options for patients with no matched donors …

hematologic malignancy
graft versus host disease
granulocyte colony stimulating factor
cell transplantation
mycophenolate mofetil
  • 0 views
  • 06 Mar, 2021
  • 1 location
Safety and Tolerability Evaluation of MaaT033

Richness and diversity of gut microbiota are increasingly found to be associated with cancer outcomes. Moreover, an adequately responsive immune system seems to rely on the existence of a functioning gut ecosystem that includes the microbiota and its natural environment. Cancer by itself, but also cancer treatments - in particular …

  • 0 views
  • 27 Jan, 2021
  • 4 locations
Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults

The purpose of the CliniMACS TCR-Biotin System and CliniMACS CD19 is to improve the safety and efficacy of allogeneic HLA-partially matched related or unrelated donors HSCT when no matched donors are available, to treat malignant and nonmalignant disorders for which HSCT is the recommended best available therapy. Initially this device …

  • 0 views
  • 22 Jul, 2021
  • 1 location
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

This is a treatment guideline for a second or greater allogeneic hematopoietic stem cell transplant (HSCT) using a reduced intensity conditioning (RIC) in patients with non-malignant or malignant diseases. This regimen, consisting of busulfan, fludarabine, and low dose total body irradiation (TBI), is designed to promote engraftment in patients who …

myeloablative conditioning
g-csf
fludarabine
total body irradiation
reduced intensity conditioning
  • 17 views
  • 21 Jul, 2021
  • 1 location