Chronic Myeloid Leukemia Clinical Trials

A listing of Chronic Myeloid Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 12 clinical trials
Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

asciminib from adult to pediatric patients will be conducted. Full extrapolation is based on the concept that CML in the pediatric population has the same pathogenesis, similar clinical characteristics and

asciminib
basophils
leukemia
  • 0 views
  • 08 Aug, 2022
  • 22 locations
Asciminib Treatment Optimization in ≥ 3rd Line CML-CP.

The purpose of the study is to optimize the treatment of asciminib in patients with chronic myelogenous leukemia in chronic phase (CML-CP) previously treated with 2 or more Tyrosine Kinase

nilotinib
asciminib
imatinib
tyrosine
leukemia
  • 0 views
  • 11 Aug, 2022
  • 37 locations
A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

The study is designed to compare the efficacy of asciminib 80 mg QD versus Investigator selected TKI for the treatment of newly diagnosed, previously untreated patients with Ph+ CML-CP. The

  • 1 views
  • 11 Aug, 2022
  • 123 locations
Dose Reduced Dasatinib (70 mg Daily) as First-line Treatment for Newly Diagnosed CML-CP

The purpose of this study is to explore the efficacy and safety of dasatinib 70 mg once daily as first line therapy in patients with early chronic phase (CP) chronic myeloid leukemia (CML

dasatinib
leukemia
  • 0 views
  • 11 Aug, 2022
  • 1 location
Treatment With Olverembatinib in CML-CP Patients Who Failed to at Least Two Previously Administered Second-generation TKIs.

The purpose of this trial is to evaluate the efficacy and safety of olverembatinib(HQP1351) in patients with chronic myeloid leukemia in chronic phase (CML-CP) who are resistant and/or

  • 0 views
  • 10 Aug, 2022
  • 1 location
Safety Study of SLC-391 in Subjects With Solid Tumors

activity against different tumour cell lines in vitro and efficacy in different animal models including nonsmall cell lung cancer (NSCLC), chronic myeloid leukemia (CML) and (acute myeloid leukemia (AML

lung cancer
targeted therapy
cancer
hormone therapy
endocrine therapy
  • 15 views
  • 09 Aug, 2022
  • 3 locations
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

This study seeks to examine treatment therapy that will reduced regimen-related toxicity and relapse while promoting rapid immune reconstitution with limited serious graft-versus-host-disease (GVHD) and also improve disease-free survival and quality of life. The investigators propose to evaluate the safety and efficacy of selective naive T-cell depleted (by TCRɑβ and …

granulocyte colony stimulating factor
cell transplantation
leukemia
thiotepa
cancer
  • 189 views
  • 10 Aug, 2022
  • 1 location
Tyrosine Kinase Inhibition to Treat Myeloid Hypereosinophilic Syndrome

dose for the treatment of chronic myelogenous leukemia. In patients who demonstrate a complete clinical and hematologic response to imatinib therapy and who do not have life-threatening disease, the

  • 4 views
  • 11 Aug, 2022
  • 1 location
Cord Blood Transplant With OTS for the Treatment of HIV Positive Hematologic Cancers

This phase II trial studies the side effects of a cord blood transplant using OTS and to see how well it works in treating patients with human immunodeficiency virus (HIV) positive hematologic (blood) cancers. After a cord blood transplant, the immune cells, including white blood cells, can take a while …

leukemia
pancytopenia
thiotepa
cancer
blast cells
  • 0 views
  • 11 Aug, 2022
  • 1 location
Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Background In allogeneic stem cell transplantation (SCT), stem cells are taken from a donor and given to a recipient. Sometimes the recipient s immune system destroys the donor s cells. Or donor immune cells attack the recipient s tissues, called graft-versus-host disease (GVHD). This is less likely when the recipient …

cell transplantation
leukemia
hla-a
acute leukemia
sirolimus
  • 23 views
  • 09 Aug, 2022
  • 2 locations