Catheter Complications Clinical Trials

A listing of Catheter Complications medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 69 clinical trials
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia

Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects up to 35% of very low birth weight infants (VLBW < 1500 g). Based on the current numbers of VLBW infants born annually in the U.S., between 5,000-10,000 neonates will develop BPD each year. It is estimated that 8-42% of …

FIO2
assisted ventilation
citrulline
pulmonary disease
pressure support
  • 1 views
  • 22 Mar, 2022
  • 1 location
Effects of Treprostinil on Right Ventricular Structure and Function in Patients With Pulmonary Arterial Hypertension

In a group of patients with PAH treated with treprostinil, the current study aims to investigate the effect of treatment on RV structure and function; and correlate changes in RV structure and function with: World Health Organisation (WHO) class, Six-minute walk test, Quality of life (QoL), and Pre-specified biomarkers (N-terminal …

nesiritide
pulmonary arterial hypertension
endothelin receptor antagonist
right heart catheterization
treprostinil
  • 9 views
  • 15 Feb, 2022
  • 1 location
ABI-009, an mTOR Inhibitor, for Patients With Severe Pulmonary Arterial Hypertension

mTOR activation has been shown to be relevant in the development and progression of pulmonary hypertension. Inhibition of mTOR has been shown to reverse or regress pulmonary hypertension in animal models. ABI-009 is an albumin-bound mTOR inhibitor with improved penetration in lung tissue.

primary pulmonary hypertension
left ventricular end-diastolic pressure
pulmonary arterial hypertension
pulmonary function test
congenital heart defects
  • 27 views
  • 26 Jan, 2022
  • 6 locations
Treatment of Pulmonary Hypertension in High-risk Cardiac Surgery Patients Using Inhalational and Intravenous Agents (levos-milr)

The aim of this study is to examine and compare the effect of Levosimendan and Milrinone administered intravenously and via inhalation respectively in cardiac surgery patients with pulmonary hypertension and right ventricular dysfunction.

levosimendan
left ventricular dysfunction
anesthesia
hypertension
  • 0 views
  • 22 Mar, 2022
  • 1 location
THERAPY-HYBRID-BPA Trial

Riociguat could improve the exercise capacity and residual symptoms in patients with chronic thromboembolic pulmonary hypertension (CTEPH) even after normalization of pulmonary arterial pressure by balloon pulmonary angioplasty (BPA). This randomized controlled trial study aimed to clarify whether the improvement of peak cardiac index (CI) during exercise maintains or not …

riociguat
right heart catheterization
  • 2 views
  • 26 Jan, 2021
  • 1 location
Levosimendan Administration in Pulmonary Hypertension (Levosim-PH)

The aim of the study is to examine the pharmacokinetics and pharmacodynamic properties of Levosimendan in cardiac surgery patients with pulmonary hypertension and impaired right ventricular function.

levosimendan
left ventricular dysfunction
anesthesia
hypertension
  • 0 views
  • 23 Mar, 2022
  • 1 location
Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia

Inhaled nitric oxide (iNO) is an effective treatment for pulmonary hypertension (PH) in term and near-term infants. Preterm infants are at risk for early PH that is associated with high risk for bronchopulmonary dysplasia or death. In multiple clinical trials, iNO treatment was not effective for BPD prevention. However, infants …

  • 0 views
  • 01 May, 2022
  • 1 location
Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension: Intervention With Repeat Dosing of eNOS-enhanced EPCs (SAPPHIRE)

The SAPPHIRE clinical trial seeks to establish the efficacy and safety of repeated monthly dosing of autologous EPCs transfected with human eNOS (heNOS) in patients with symptomatic severe PAH on available PAH-targeted medical therapy.

assisted ventilation
left ventricular end-diastolic pressure
heart disease
pulmonary arterial hypertension
pulmonary arterial pressure
  • 10 views
  • 18 May, 2022
  • 6 locations
Hemodynamic Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension (HEXA)

To study hemodynamic effects of acute normobaric hypoxia during exercise in patients with pulmonary hypertension in a single-center randomized controlled trial.

hypoxia
  • 0 views
  • 04 Jun, 2022
  • 1 location
Hemodynamic Effects During Exercise in Patients With Pulmonary Hypertension Receiving Sildenafil (HEXASN)

To study hemodynamic effects of Sildenafil during exercise in patients with pulmonary hypertension.

sildenafil
  • 0 views
  • 05 Jun, 2022
  • 2 locations