Catheter Complications Clinical Trials

A listing of Catheter Complications medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
A Phase 2/3, Multicenter, Randomized, Double-blind, Placebo-Controlled, Adaptive Design Study to Evaluate the Efficacy and Safety of MK-5475 in Adults With Pulmonary Arterial Hypertension

This is a two-part (Phase 2/Phase 3) study of MK-5475, an inhaled soluble guanylate cyclase stimulator, in participants with pulmonary arterial hypertension (PAH). The first part (Phase 2) will assess three different doses of MK-5475 compared to placebo in a base period of 12 weeks, followed by comparison of three …

right heart catheterization
heart disease
body mass index
left ventricular end-diastolic pressure
pulmonary arterial hypertension
  • 37 views
  • 15 Sep, 2022
  • 74 locations
Prospective, Non-randomized, Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients With Pulmonary Hypertension (AFR-Prophet)

This study aims to investigate safety and efficacy of Occlutech® AFR device in patients with severe pulmonary hypertension (PH).

right ventricular failure
pulmonary arterial pressure
heart failure
  • 46 views
  • 17 Sep, 2022
  • 6 locations
A Phase 3, Randomized, Placebo-controlled, Double-blind, Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Patients With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD) (PERFECT)

The primary objective of this study is to demonstrate the efficacy of inhaled treprostinil compared to placebo in improving exercise ability as measured by change from baseline in 6-Minute Walk Distance (6MWD) following 12 weeks of active treatment in participants with PH-COPD.

right heart catheterization
forced expiratory volume
diuretics
vasodilator
left ventricular end-diastolic pressure
  • 2674 views
  • 15 Sep, 2022
  • 66 locations
A Randomized, Double-Blind, Placebo-Controlled Dose Escalation and Verification Clinical Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide (iNO) in Subjects at Risk of Pulmonary Hypertension Associated With Pulmonary Fibrosis on Long Term Oxygen Therapy (Part 1 and Part 2) - REBUILD (REBUILD)

A randomized, double-blind, placebo-controlled dose escalation and verification study to assess the safety and efficacy of pulsed inhaled nitric oxide (iNO) in subjects at risk for pulmonary hypertension associated with pulmonary fibrosis on long term oxygen therapy (Part 1 and Part 2) - REBUILD

emphysema
pneumonia
pulmonary arterial pressure
vasodilator
dyspnea
  • 392 views
  • 19 Sep, 2022
  • 61 locations
Autologous Stem Cell Transplantation With CD34-Selected Peripheral Blood Stem Cells (PBSC) in Patients With Treatment Resistant Systemic Sclerosis (SSc) (SSc)

The purpose of this study is to determine whether a regimen of high-dose immunoablative therapy will demonstrate safety that is consistent or improved with other published regimens in SSc patients, while maintaining a treatment effect.

rituximab
ct scan
raynaud's syndrome
total body irradiation
cyclophosphamide
  • 216 views
  • 20 Sep, 2022
  • 2 locations
Is Routine Urinary Bladder Catheterization Necessary After Ureteroscopy and Double J Stent Placement?

After semirigid or flexible ureteroscopy operations where a DJ stent was placed, there is diversity in practice of placing a urethral catheter. The presence of vesico-ureteral reflux due to DJ stents has been proven to exist and can cause flank pain and UTI due to retrograde urine flow. The main …

  • 0 views
  • 17 Sep, 2022
  • 1 location
Drug Use Investigation of Riociguat for ChronicThromboembolic Pulmonary Hypertension (CTEPH) (JPMS-CTEPH)

This local, prospective, non-interventional, multi-center study includes patients treated with Riociguat for inoperable CTEPH(Chronic thromboembolic pulmonary hypertension)/ persistent or recurrent CTEPH after surgical treatment. It is planned to include a total of 400 patients (valid for safety analysis). This study is performed as an all-case investigation. The treatment of Riociguat …

adempas
chronic thromboembolic pulmonary hypertension
riociguat
  • 7 views
  • 16 Sep, 2022
  • 1 location
Drug Use Investigation of Ventavis for Pulmonary Arterial Hypertension (PAH)

This study is collecting post-marketing information on the safety and effectiveness of Ventavis under the routine clinical practice for patients with PAH

pulmonary arterial hypertension
ventavis
iloprost
  • 0 views
  • 19 Sep, 2022
  • 1 location
A Natural History Study of Novel Biomarkers in Pulmonary Arterial Hypertension

Background High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. Some people have disease-associated PAH and some have PAH from an unknown cause. Researchers want to follow the natural history of all PAH patients to understand how PAH progresses in order to discover …

left ventricular end-diastolic pressure
walk tests
pulmonary arterial hypertension
pulmonary function test
Accepts healthy volunteers
  • 61 views
  • 14 Sep, 2022
  • 1 location
Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study (NRG-1-CVDs)

This is an observational study of Neuregulin-1 (NRG-1) plasma levels in patients with different forms of cardiovascular disease including microvascular angina (MVA), heart failure with preserved ejection fraction (HFpEF), as well as, heart failure with reduced ejection fraction (HFrEF) and pulmonary hypertension (PH). Investigators intend to identify cardiovascular diseases which …

natriuretic peptide
diastolic dysfunction
chest pain
stenosis
valvular disease
  • 0 views
  • 20 Aug, 2022
  • 1 location