Catheter Complications Clinical Trials

A listing of Catheter Complications medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 31 clinical trials
Clinical Pharmacy for Patients With a PICC Line (CLIPICC)

Clinical pharmacy is a patient-centered discipline and improves significantly the safety of drug management. Regarding medications, clinical pharmacy is efficient. The investigator hypothesize that clinical pharmacy applied to medical devices could be as effective as in the medication field. The main objective of this study is to assess the effectiveness …

  • 0 views
  • 17 Jun, 2022
  • 1 location
A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD) (PERFECT)

The primary objective of this study is to demonstrate the efficacy of inhaled treprostinil compared to placebo in improving exercise ability as measured by change from baseline in 6-Minute Walk Distance (6MWD) following 12 weeks of active treatment in participants with PH-COPD.

diuretics
left ventricular end-diastolic pressure
vasodilator
treprostinil
right heart catheterization
  • 2667 views
  • 10 May, 2022
  • 64 locations
This Study Tests the Safety of Inhaled BAY1237592, How the Drug is Tolerated and How it Effects Patients With High Blood Pressure in the Arteries of the Lungs in the Two Different Disease Groups Pulmonary Arterial Hypertension (PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH) (ATMOS)

In this trial the effects of the inhaled drug BAY1237592 will be studied in patients with high blood pressure in the pulmonary blood vessels due to Pulmonary Arterial Hypertension (PAH) and due to Chronic Thromboembolic Pulmonary Hypertension (CTEPH). Pulmonary hypertension is characterized by the elevation of pressure in the pulmonary …

endothelin receptor antagonist
iloprost
endothelin
prostaglandin
chronic thromboembolic pulmonary hypertension
  • 153 views
  • 07 Jun, 2022
  • 22 locations
A Study of the Efficacy and Safety of MK-5475 in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)

This is a two-part (Phase 2/Phase 3) study of MK-5475, an inhaled soluble guanylate cyclase stimulator, in participants with pulmonary arterial hypertension (PAH). The first part (Phase 2) will assess three different doses of MK-5475 compared to placebo in a base period of 12 weeks, followed by comparison of three …

heart disease
left ventricular end-diastolic pressure
pulmonary arterial hypertension
right heart catheterization
body mass index
  • 36 views
  • 27 Jun, 2022
  • 69 locations
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension (SALTO)

The purpose of this study is to evaluate whether the addition of selexipag to standard of care treatment delays disease progression in children with Pulmonary Arterial Hypertension (PAH) in comparison to placebo.

heart disease
endothelin receptor antagonist
pulmonary arterial hypertension
right heart catheterization
endothelin
  • 247 views
  • 01 Jul, 2022
  • 85 locations
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

endothelin receptor antagonist
angiotensin ii
calcium
ralinepag
digoxin
  • 6444 views
  • 20 Jun, 2022
  • 226 locations
Nylon Versus Polyurethane Epidural Catheters In Patients Undergoing Major Orthopedic Surgery

Objectives: To compare the safety and efficacy of nylon (polyamide) epidural catheter versus polyurethane epidural catheter in patients undergoing major orthopedic surgery under continuous epidural anesthesia. Background: Continuous epidural anesthesia is the most common anesthetic technique used in orthopedic surgery. However, the use of epidural catheters is associated with complications. …

  • 0 views
  • 04 May, 2022
  • 1 location
Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia

Inhaled nitric oxide (iNO) is an effective treatment for pulmonary hypertension (PH) in term and near-term infants. Preterm infants are at risk for early PH that is associated with high risk for bronchopulmonary dysplasia or death. In multiple clinical trials, iNO treatment was not effective for BPD prevention. However, infants …

  • 0 views
  • 01 May, 2022
  • 1 location
Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension: Intervention With Repeat Dosing of eNOS-enhanced EPCs (SAPPHIRE)

The SAPPHIRE clinical trial seeks to establish the efficacy and safety of repeated monthly dosing of autologous EPCs transfected with human eNOS (heNOS) in patients with symptomatic severe PAH on available PAH-targeted medical therapy.

congenital heart defects
heart disease
oxygen saturation
left ventricular end-diastolic pressure
prostaglandin
  • 10 views
  • 18 May, 2022
  • 6 locations
Hemodynamic Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension (HEXA)

To study hemodynamic effects of acute normobaric hypoxia during exercise in patients with pulmonary hypertension in a single-center randomized controlled trial.

hypoxia
  • 0 views
  • 04 Jun, 2022
  • 1 location